Patents by Inventor Nils Ove Gustafsson

Nils Ove Gustafsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHOLESTYRAMINE PELLETS, ORAL CHOLESTYRAMINE FORMULATIONS, AND USES THEREOF
    Publication number: 20200046757
    Abstract: The invention relates to a population of pellets, each pellet comprising cholestyramine and at least about 5% w/w of an acrylate copolymer. The invention also relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets and wherein said pellets are coated with a colon release coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption.
    Type: Application
    Filed: August 9, 2019
    Publication date: February 13, 2020
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Nils-Olof Lindberg, Jessica Elversson
  • ORAL CHOLESTYRAMINE FORMULATION AND USE THEREOF
    Publication number: 20200046635
    Abstract: The invention relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a colon release coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption.
    Type: Application
    Filed: August 9, 2018
    Publication date: February 13, 2020
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Nils-Olof Lindberg, Jessica Elversson
  • ORAL CHOLESTYRAMINE FORMULATION AND USE THEREOF
    Publication number: 20200046758
    Abstract: The invention relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a diffusion-controlled inner coating and an enteric outer coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption.
    Type: Application
    Filed: August 9, 2019
    Publication date: February 13, 2020
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Nils-Olof Lindberg, Jessica Elversson
  • ORAL CHOLESTYRAMINE FORMULATION AND USE THEREOF
    Publication number: 20200046636
    Abstract: The invention relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a diffusion-controlled inner coating and an enteric outer coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption.
    Type: Application
    Filed: August 9, 2018
    Publication date: February 13, 2020
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Nils-Olof Lindberg, Jessica Elversson
  • CRYSTAL MODIFICATIONS OF ODEVIXIBAT
    Publication number: 20200002299
    Abstract: The present invention relates to crystal modifications of 1,1-dioxo-3,3-dibutyl-5-phenyl-7-methylthio-8-(N—{(R)-?-[N—((S)-1-carboxypropyl)carbamoyl]-4-hydroxybenzyl}carbamoylmethoxy)-2,3,4,5-tetrahydro-1,2,5-benzothiadiazepine (odevixibat), more specifically crystal modifications 1 and 2 of odevixibat. The invention also relates to a process for the preparation of crystal modification 1 of odevixibat, to a pharmaceutical composition comprising crystal modification 1, and to the use of this crystal modification in the treatment of various conditions as described herein.
    Type: Application
    Filed: July 10, 2019
    Publication date: January 2, 2020
    Inventors: Robert Lundqvist, Ingvar Ymen, Martin Bohlin, Eva Byröd, Per-Göran Gillberg, Anna-Maria Tivert, Rikard Bryland, Ann-Charlotte Dahlquist, Jessica Elversson, Nils Ove Gustafsson
  • Oral cholestyramine formulation and use thereof
    Patent number: 10493096
    Abstract: The invention relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a colon release coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: December 3, 2019
    Assignee: Albireo AB
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Nils-Olof Lindberg, Jessica Elversson
  • Cholestyramine pellets and methods for preparation thereof
    Patent number: 10441604
    Abstract: The invention relates to small cholestyramine pellets that can be prepared by extrusion. The pellets have a high cholestyramine loading and are stable enough to be coated with one or more coating layers. The invention also relates to a process for the preparation of such pellets and to a multiparticulate drug delivery system comprising such pellets.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: October 15, 2019
    Assignee: Albireo AB
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Nils-Olof Lindberg, Jessica Elversson
  • Oral cholestyramine formulation and use thereof
    Patent number: 10441605
    Abstract: The invention relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a colon release coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: October 15, 2019
    Assignee: Albireo AB
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Nils-Olof Lindberg, Jessica Elversson
  • DELAYED RELEASE PHARMACEUTICAL FORMULATIONS COMPRISING VALPROIC ACID, AND USES THEREOF
    Publication number: 20190111011
    Abstract: There is provided herein a pharmaceutical formulation having one or more component comprising valproic acid (VPA) and/or a pharmaceutically acceptable salt thereof; and one or more secondary acid, and optionally comprising one or more pharmaceutically acceptable excipient. There is also provided uses of such formulations.
    Type: Application
    Filed: April 10, 2017
    Publication date: April 18, 2019
    Inventors: Nils Ove Gustafsson, Hans Martensson, Niklas Bergh, Jonas Faijerson Saljo, Sverker Jem
  • CHOLESTYRAMINE GRANULES, ORAL CHOLESTYRAMINE FORMULATIONS AND USE THEREOF
    Publication number: 20190070217
    Abstract: The invention relates to small granules comprising cholestyramine. The granules have a high cholestyramine content and are stable enough to be coated with one or more coating layers. The invention also relates to a multiparticulate drug delivery system comprising such granules. The invention further relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine granules that are coated with a colon release coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption and bile acid diarrhoea.
    Type: Application
    Filed: September 7, 2018
    Publication date: March 7, 2019
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Kurt Lövgren
  • CHOLESTYRAMINE PELLETS, ORAL CHOLESTYRAMINE FORMULATIONS AND USE THEREOF
    Publication number: 20190046451
    Abstract: The invention relates to small pellets comprising cholestyramine. The pellets have a high cholestyramine content and are stable enough to be coated with one or more coating layers. The invention also relates to a multiparticulate drug delivery system comprising such pellets. The invention further relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a colon release coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption and bile acid diarrhoea.
    Type: Application
    Filed: September 7, 2018
    Publication date: February 14, 2019
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Kurt Lövgren
  • ORAL CHOLESTYRAMINE FORMULATION AND USE THEREOF
    Publication number: 20180360870
    Abstract: The invention relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a colon release coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption.
    Type: Application
    Filed: May 24, 2018
    Publication date: December 20, 2018
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Nils-Olof Lindberg, Jessica Elversson
  • ORAL CHOLESTYRAMINE FORMULATION AND USE THEREOF
    Publication number: 20180360871
    Abstract: The invention relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a colon release coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption.
    Type: Application
    Filed: May 24, 2018
    Publication date: December 20, 2018
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Nils-Olof Lindberg, Jessica Elversson
  • ORAL CHOLESTYRAMINE FORMULATION AND USE THEREOF
    Publication number: 20180360869
    Abstract: The invention relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a diffusion-controlled inner coating and an enteric outer coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption.
    Type: Application
    Filed: May 24, 2018
    Publication date: December 20, 2018
    Inventors: Per-Göran Gillberg, Nils OVe Gustafsson, Nils-Olof Lindberg, Jessica Elversson
  • CHOLESTYRAMINE PELLETS AND METHODS FOR PREPARATION THEREOF
    Publication number: 20180264031
    Abstract: The invention relates to small cholestyramine pellets that can be prepared by extrusion. The pellets have a high cholestyramine loading and are stable enough to be coated with one or more coating layers. The invention also relates to a process for the preparation of such pellets and to a multiparticulate drug delivery system comprising such pellets.
    Type: Application
    Filed: May 24, 2018
    Publication date: September 20, 2018
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Nils-Olof Lindberg, Jessica Elversson
  • ORAL CHOLESTYRAMINE FORMULATION AND USE THEREOF
    Publication number: 20180264029
    Abstract: The invention relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a diffusion-controlled inner coating and an enteric outer coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption.
    Type: Application
    Filed: May 24, 2018
    Publication date: September 20, 2018
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Nils-Olof Lindberg, Jessica Elversson
  • CHOLESTYRAMINE PELLETS AND METHODS FOR PREPARATION THEREOF
    Publication number: 20180264030
    Abstract: The invention relates to small cholestyramine pellets that can be prepared by extrusion. The pellets have a high cholestyramine loading and are stable enough to be coated with one or more coating layers. The invention also relates to a process for the preparation of such pellets and to a multiparticulate drug delivery system comprising such pellets.
    Type: Application
    Filed: May 24, 2018
    Publication date: September 20, 2018
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Nils-Olof Lindberg, Jessica Elversson
  • ORAL CHOLESTYRAMINE FORMULATION AND USE THEREOF
    Publication number: 20170224721
    Abstract: The invention relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a colon release coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption.
    Type: Application
    Filed: March 3, 2017
    Publication date: August 10, 2017
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Nils-Olof Lindberg, Jessica Elversson
  • CHOLESTYRAMINE PELLETS AND METHODS FOR PREPARATION THEREOF
    Publication number: 20170224719
    Abstract: The invention relates to small cholestyramine pellets that can be prepared by extrusion. The pellets have a high cholestyramine loading and are stable enough to be coated with one or more coating layers. The invention also relates to a process for the preparation of such pellets and to a multiparticulate drug delivery system comprising such pellets.
    Type: Application
    Filed: March 3, 2017
    Publication date: August 10, 2017
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Nils-Olof Lindberg, Jessica Elversson
  • ORAL CHOLESTYRAMINE FORMULATION AND USE THEREOF
    Publication number: 20170224720
    Abstract: The invention relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a diffusion-controlled inner coating and an enteric outer coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption.
    Type: Application
    Filed: March 3, 2017
    Publication date: August 10, 2017
    Inventors: Per-Göran Gillberg, Nils Ove Gustafsson, Nils-Olof Lindberg, Jessica Elversson