Abstract: A medical imaging system includes a robotic arm carrying a fluoroscopic imager for generating fluoroscopic image data of anatomy along a beam axis. The arm can adjust a relative position between the fluoroscopic imager and the anatomy. A video imager generates video image data of the anatomy along a sightline axis. A marker is positionable relative to the anatomy and defines a feature for capture in the fluoroscopic and video image data. A processor is configured to execute instructions upon the fluoroscopic and video image data and: (a) register a reference position of the feature relative to the anatomy in the fluoroscopic and video image data; and (b) generate an augmented image stream showing the fluoroscopic or video image data overlaid onto the other such that the reference positions are co-registered. The system includes a display configured to present the augmented image stream of the anatomy substantially in real time.