Patents by Inventor Nimali Piyushika Withana

Nimali Piyushika Withana has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of breast cancer using combination therapies comprising an AKT inhibitor, a taxane, and a PD-L1 inhibitor
    Patent number: 11701356
    Abstract: Provided herein are combination therapies comprising an AKT inhibitor, a PD-L1 antibody, and taxane for use in treating MTNBC and locally advanced TNBC.
    Type: Grant
    Filed: December 17, 2019
    Date of Patent: July 18, 2023
    Assignee: GENENTECH, INC.
    Inventors: Nimali Piyushika Withana, Aruna Mani, Stina Mui Singel
  • TREATMENT OF BREAST CANCER USING COMBINATION THERAPIES COMPRISING AN AKT INHIBITOR, A TAXANE, AND A PD-L1 INHIBITOR
    Publication number: 20200197396
    Abstract: Provided herein are combination therapies comprising an AKT inhibitor, a PD-L1 antibody, and taxane for use in treating MTNBC and locally advanced TNBC.
    Type: Application
    Filed: December 17, 2019
    Publication date: June 25, 2020
    Applicant: Genentech, Inc.
    Inventors: NIMALI PIYUSHIKA WITHANA, ARUNA MANI, STINA MUI SINGEL
  • Control of gene expression in plants
    Patent number: 8921538
    Abstract: The invention provides the isolated promoter polynucleotide sequence of SEQ ID NO: 1 from perennial ryegrass (Lolium perenne L.), and fragments and variants thereof. The invention also provides constructs, plant cells and plant genetically modified to contain the promoter polynucleotide. The invention also provides methods for producing plants with altered gene expression and traits via genetic transformation of plants with the promoter polynucleotide.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: December 30, 2014
    Assignee: Vialactia Biosciences (NZ) Limited
    Inventors: Sathish Puthigae, Jonathan Robert Phillips, Nimali Piyushika Withana, Claudia Jeannette Smith-Espinoza, Catherine Jane Bryant, Shivendra Bajaj, Kerry Robert Templeton
  • Gene expression control in plants
    Patent number: 8669108
    Abstract: The invention provides the isolated promoter polynucleotide sequence of SEQ ID NO:1, and fragments and variants thereof. The invention also provides constructs, plant cells and plants genetically modified to contain the promoter polynucleotide. The invention also provides methods for producing plants with altered gene expression and traits via genetic transformation of plants with the promoter polynucleotides.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: March 11, 2014
    Assignee: Vialactia Biosciences (NZ) Limited
    Inventors: Sathish Puthigae, Jonathan Robert Phillips, Nimali Piyushika Withana, Claudia Jeannette Smith-Espinoza, Catherine Jane Bryant, Kerry Robert Templeton, Shivendra Bajaj
  • CONTROL OF GENE EXPRESSION IN PLANTS
    Publication number: 20120084880
    Abstract: The invention provides the isolated promoter polynucleotide sequence of SEQ ID NO: 1 from perennial ryegrass (Lolium perenne L.), and fragments and variants thereof. The invention also provides constructs, plant cells and plant genetically modified to contain the promoter polynucleotide. The invention also provides methods for producing plants with altered gene expression and traits via genetic transformation of plants with the promoter polynucleotide.
    Type: Application
    Filed: March 26, 2010
    Publication date: April 5, 2012
    Applicant: Vialactia Biosciences (NZ) Limited
    Inventors: Sathish Puthigae, Jonathan Robert Phillips, Nimali Piyushika Withana, Claudia Jeannette Smith-Espinoza, Catherine Jane Bryant, Shivendra Bajaj, Kerry Robert Templeton
  • GENE EXPRESSION CONTROL IN PLANTS
    Publication number: 20110179517
    Abstract: The invention provides the isolated promoter polynucleotide sequence of SEQ ID NO:1, and fragments and variants thereof. The invention also provides constructs, plant cells and plants genetically modified to contain the promoter polynucleotide. The invention also provides methods for producing plants with altered gene expression and traits via genetic transformation of plants with the promoter polynucleotides.
    Type: Application
    Filed: March 30, 2009
    Publication date: July 21, 2011
    Inventors: Sathish Puthigae, Jonathan Robert Phillips, Nimali Piyushika Withana, Claudia Jeannette Smith-Espinoza, Catherine Jane Bryant, Kerry Robert Templeton, Shivendra Bajaj
  • CONTROL OF PLANT GENE EXPRESSION
    Publication number: 20100293664
    Abstract: This invention provides an isolated promoter polynucleotide comprising the sequence of SEQ ID NO:1, and variants and fragments thereof capable of controlling transcription of an operably linked polynucleotide in a plant. The invention also provides the constructs, vectors, host cells, plant cells and plants transformed with the isolated promoter polynucleotide. The invention also provides methods of use of the isolated promoter polynucleotide.
    Type: Application
    Filed: April 3, 2008
    Publication date: November 18, 2010
    Inventors: Sathish Puthigae, Jonathan Robert Phillips, Nimali Piyushika Withana, Claudia Jeannette Smith-Espinoza, Catherine Jane Bryant, Shivendra Bajaj, Kerry Robert Templeton