Patents by Inventor Nina Funa

Nina Funa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EFFICIENT INDUCTION OF DEFINITIVE ENDODERM FROM PLURIPOTENT STEM CELLS
    Publication number: 20200190477
    Abstract: The present invention relates to a method to differentiate pluripotent stem cells to a primitive streak cell population, in a stepwise manner for further maturation to definitive endoderm.
    Type: Application
    Filed: November 25, 2019
    Publication date: June 18, 2020
    Inventors: Nina Funa, Katja Hess, Jenny Ekberg, Henrik Semb
  • Efficient induction of definitive endoderm from pluripotent stem cells
    Patent number: 10487313
    Abstract: The present invention relates to a method to differentiate pluripotent stem cells to a primitive streak cell population, in a stepwise manner for further maturation to definitive endoderm.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: November 26, 2019
    Assignees: Novo Nordisk A/S, Takara Bio Europe AB
    Inventors: Nina Funa, Katja Hess, Jenny Ekberg, Henrik Semb
  • Generation of pancreatic endoderm from pluripotent stem cells using small molecules
    Publication number: 20190153394
    Abstract: A method of producing pancreatic cells or pancreatic cell precursors expressing at least 5% PDX1/NKX6.1 double positive, comprising exposing definitive endoderm cells to an effective amount of one or more small molecules, to differentiate the human definitive endoderm cells into the pancreatic cells or pancreatic cell precursors. The present invention also relates to pancreatic endoderm cells produced by said methods and uses of said pancreatic endoderm cells.
    Type: Application
    Filed: January 23, 2019
    Publication date: May 23, 2019
    Inventors: Jenny Ekberg, Mattias Hansson, Ulrik Doehn, Katja Hess, Nina Funa
  • Generation of pancreatic endoderm from pluripotent stem cells using small molecules
    Patent number: 10221392
    Abstract: A method of producing pancreatic cells or pancreatic cell precursors expressing at least 5% PDX1/NKX6.1 double positive, comprising exposing definitive endoderm cells to an effective amount of one or more small molecules, to differentiate the human definitive endoderm cells into the pancreatic cells or pancreatic cell precursors. The present invention also relates to pancreatic endoderm cells produced by said methods and uses of said pancreatic endoderm cells.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: March 5, 2019
    Assignees: Novo Nordisk A/S, TAKARA BIO EUROPE AB
    Inventors: Jenny Ekberg, Mattias Hansson, Ulrik Doehn, Katja Hess, Nina Funa
  • EFFICIENT INDUCTION OF DEFINITIVE ENDODERM FROM PLURIPOTENT STEM CELLS
    Publication number: 20180002668
    Abstract: The present invention relates to a method to differentiate pluripotent stem cells to a primitive streak cell population, in a stepwise manner for further maturation to definitive endoderm.
    Type: Application
    Filed: September 15, 2017
    Publication date: January 4, 2018
    Applicants: Novo Nordisk A/S, Takara Bio Europe AB, Takara Bio Europe AB
    Inventors: Nina Funa, Katja Hess, Jenny Ekberg, Henrik Semb
  • Generation of Pancreatic Endoderm from Pluripotent Stem Cells using Small Molecules
    Publication number: 20160326495
    Abstract: A method of producing pancreatic cells or pancreatic cell precursors expressing at least 5% PDX1/NKX6.1 double positive, comprising exposing definitive endoderm cells to an effective amount of one or more small molecules, to differentiate the human definitive endoderm cells into the pancreatic cells or pancreatic cell precursors. The present invention also relates to pancreatic endoderm cells produced by said methods and uses of said pancreatic endoderm cells.
    Type: Application
    Filed: July 21, 2016
    Publication date: November 10, 2016
    Inventors: Jenny Ekberg, Mattias Hansson, Ulrik Doehn, Katja Hess, Nina Funa
  • Generation of pancreatic endoderm from Pluripotent Stem cells using small molecules
    Publication number: 20150247123
    Abstract: A method of producing pancreatic cells or pancreatic cell precursors expressing at least 5% PDX1/NKX6.1 double positive, comprising exposing definitive endoderm cells to an effective amount of one or more small molecules, to differentiate the human definitive endoderm cells into the pancreatic cells or pancreatic cell precursors. The present invention also relates to pancreatic endoderm cells produced by said methods and uses of said pancreatic endoderm cells.
    Type: Application
    Filed: September 3, 2013
    Publication date: September 3, 2015
    Inventors: Jenny Ekberg, Mattias Hansson, Ulrik Doehn, Katja Hess, Nina Funa
  • EFFICIENT INDUCTION OF DEFINITIVE ENDODERM FROM PLURIPOTENT STEM CELLS
    Publication number: 20140234963
    Abstract: The present invention relates to a method to differentiate pluripotent stem cells to a primitive streak cell population, in a stepwise manner for further maturation to definitive endoderm.
    Type: Application
    Filed: June 21, 2012
    Publication date: August 21, 2014
    Applicant: Novo Nordisk A/S
    Inventors: Nina Funa, Katja Hess, Jenny Ekberg, Henrik Semb