Patents by Inventor Nina Moran
Nina Moran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210238656Abstract: The present invention relates to means for collection of biological samples. Specifically, the present invention provides a solid support for collection, storage and subsequent analysis of a biological sample as well as methods for use of the solid support of the invention and a kit comprising the solid support of the invention.Type: ApplicationFiled: April 22, 2021Publication date: August 5, 2021Inventors: Peter James Tatnell, Nina Moran
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Patent number: 10744499Abstract: A biological sample holder for holding a solid phase sample, including a handle, and a seal area suitable for being received in an opening of a sample receiving chamber of a cassette, mountable to a sample analysis instrument. The holder further includes a stem connected to the seal and a sample retainer connected to the stem for retaining solids in the retainer, the sample retainer including a perforated wall region for allowing fluids to pass through the wall but preventing the solid phase sample from passing through the wall.Type: GrantFiled: April 17, 2014Date of Patent: August 18, 2020Assignee: GE Healthcare UK LimitedInventors: Nina Moran, Michael John Smith, Geraint Seymour, Samantha Jane Ogden, Leonard Goren
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Patent number: 10392651Abstract: A fluidic device is disclosed for processing a biological sample in order to extract nucleic acids contained in said sample and for subsequently amplifying said extracted nucleic acids, said device including a processed sample storage archive area 10 comprising an absorbent solid substrate 14 treated with at least one nucleic acid stabilizing reagent or reagent mix, said substrate allowing the generally dry and stabilized storage of said extracted and/or amplified nucleic acids, for example for long term storage of biological samples recovered forensically.Type: GrantFiled: February 20, 2015Date of Patent: August 27, 2019Assignee: GE Healthcare UK LimitedInventor: Nina Moran
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Publication number: 20190048394Abstract: The present invention relates to means for collection of biological samples. Specifically, the present invention provides a solid support for collection, storage and subsequent analysis of a biological sample as well as methods for use of the solid support of the invention and a kit comprising the solid support of the invention.Type: ApplicationFiled: February 28, 2017Publication date: February 14, 2019Inventors: Peter James Tatnell, Nina Moran
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Publication number: 20180257077Abstract: Instruments, devices and methods of analysis are provided which fully integrate a significant number of process steps in a continuous operation. Accurate positioning and full contact between components is also provided by the relative movement the designs allow. An effect interface between a low cost disposable cartridge or device and the instrument to process it is also detailed.Type: ApplicationFiled: January 10, 2018Publication date: September 13, 2018Inventors: Frederic ZENHAUSERN, Alan NORDQUIST, Ralf LENIGK, Cedric HURTH, Jianing YANG, Xiaojia CHEN, John LEE-EDGHILL, Nina MORAN, Andrew HOPWOOD, Pieris KOUMI
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Publication number: 20170087553Abstract: A method and device structure are provided which enable an archive sample to be collected and detached relative to a device within which a series of processes, such as PCR are being provided. A chamber structure and method of use are provided in which a controlled and precise volume is obtained by control of the relative resistance to flow through various channels.Type: ApplicationFiled: September 2, 2016Publication date: March 30, 2017Inventors: Frederic ZENHAUSERN, Alan NORDQUIST, Ralf LENIGK, Cedric HURTH, Jianing YANG, Xiaojia CHEN, Matthew ESTES, John LEE-EDGHILL, Nina MORAN, Andrew HOPWOOD, Pieris KOUMI, Zhi CAI
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Publication number: 20170051334Abstract: A fluidic device is disclosed for processing a biological sample in order to extract nucleic acids contained in said sample and for subsequently amplifying said extracted nucleic acids, said device including a processed sample storage archive area 10 comprising an absorbent solid substrate 14 treated with at least one nucleic acid stabilising reagent or reagent mix, said substrate allowing the generally dry and stabilised storage of said extracted and/or amplified nucleic acids, for example for long term storage of biological samples recovered forensically.Type: ApplicationFiled: February 20, 2015Publication date: February 23, 2017Inventor: Nina Moran
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Publication number: 20160187293Abstract: An electrophoresis device where the end of the electrophoresis channel has a part that extends vertically. The electrophoresis channel includes a first access port at one end of the channel and a second port at the other end of the channel, which are in the same horizontal plane. In this way, there is a less than 0.1% hydrostatic pressure differential between two ports and the performance of the device is improved.Type: ApplicationFiled: June 11, 2012Publication date: June 30, 2016Applicants: The Arizona Board of Regents acting for and on behalf of University of Arizona, BioAccelInventors: Frederic ZENHAUSERN, Alan NORDQUIST, Ralf LENIGK, Cedric HURTH, Jianing YANG, Xiaojia CHEN, Matthew ESTES, John LEE-EDGHILL, Nina MORAN, Andrew HOPWOOD, Pieris KOUMI
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Publication number: 20160074859Abstract: A biological sample holder for holding a solid phase sample, including a handle, and a seal area suitable for being received in an opening of a sample receiving chamber of a cassette, mountable to a sample analysis instrument. The holder further includes a stem connected to the seal and a sample retainer connected to the stem for retaining solids in the retainer, the sample retainer including a perforated wall region for allowing fluids to pass through the wall but preventing the solid phase sample from passing through the wall.Type: ApplicationFiled: April 30, 2013Publication date: March 17, 2016Inventors: Nina MORAN, Michael John SMITH, Geraint SEYMOUR, Samantha Jane OGDEN, Leonard GOREN
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Publication number: 20150111215Abstract: The invention provides containers and methods of use for the storage, transportation and preparation of samples, such as DNA samples for analysis. The container is pre-provided with the reagents in sealed chambers. The sample can be introduced and the container manipulated to release the reagents, provide the necessary conditions and give a fully prepared sample. The container can then be engaged with an analysis device to identify characteristics of the sample or perform other operations thereon.Type: ApplicationFiled: May 21, 2014Publication date: April 23, 2015Applicant: FORENSIC SCIENCE SERVICE LIMITEDInventors: Gary ROSS, Sebastian WETHERALL, Owen EVANS, Andrew HOPWOOD, Nina MORAN
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Publication number: 20140178938Abstract: A method and device structure are provided which enable an archive sample to be collected and detached relative to a device within which a series of processes, such as PCR are being provided. A chamber structure and method of use are provided in which a controlled and precise volume is obtained by control of the relative resistance to flow through various channels.Type: ApplicationFiled: July 8, 2013Publication date: June 26, 2014Inventors: Frederic ZENHAUSERN, Alan NORDQUIST, Ralf LENIGK, Cedric HURTH, Jianing YANG, Xiaojia CHEN, Matthew ESTES, John LEE-EDGHILL, Nina MORAN, Andrew HOPWOOD, Pieris KOUMI, Zhi CAI
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Publication number: 20140116121Abstract: Instruments, devices and methods of analysis are provided which fully integrate a significant number of process steps in a continuous operation. Accurate positioning and full contact between components is also provided by the relative movement the designs allow. An effect interface between a low cost disposable cartridge or device and the instrument to process it is also detailed.Type: ApplicationFiled: January 3, 2014Publication date: May 1, 2014Applicant: BioAccelInventors: Frederic ZENHAUSERN, Alan NORDQUIST, Ralf LENIGK, Cedric HURTH, Jianing YANG, Xiaojia CHEN, John LEE-EDGHILL, Nina MORAN, Andrew HOPWOOD, Pieris KOUMI
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Patent number: 8640555Abstract: Instruments, devices and methods of analysis are provided which fully integrate a significant number of process steps in a continuous operation. Accurate positioning and full contact between components is also provided by the relative movement the designs allow. An effect interface between a low cost disposable cartridge or device and the instrument to process it is also detailed.Type: GrantFiled: February 9, 2010Date of Patent: February 4, 2014Assignee: BioAccelInventors: Frederic Zenhausern, Alan Nordquist, Ralf Lenigk, Cedric Hurth, Jianing Yang, Xiaojia Chen, John Lee-Edghill, Nina Moran, Andrew Hopwood, Pieris Koumi
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Publication number: 20130323737Abstract: A method and system for analysing a sample are provided, wherein one or more process steps and/or sample processors are provided separately from the instrument, for instance a sample receiving step and sample preparation step and sample extraction step and sample retention step and/or purification step and washing step and elution step, and one or more process steps and/or sample processors provided by the instrument as an integrated set, the one or more process steps and/or sample processors provided by the instrument including a sample receiving step and amplification step and denaturing step and investigation step and detection step and results analysis step and results output step. Other combinations of the split in location of the steps are possible. The optimisation of the split allows the accurate processing by a cartridge based instrument of the sample, whilst fully interfacing with a variety of sample collection and/or preparation approaches.Type: ApplicationFiled: August 10, 2011Publication date: December 5, 2013Applicant: BIOACCELInventors: Frederic Zenhausern, Alan Nordquist, Ralf Lenigk, Cedric Hurth, Jianing Yang, Xiaojia Chen, Matthew Estes, John Lee-Edghill, Nina Moran, Andrew Hopwood, Pieris Koumi
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Publication number: 20130316335Abstract: The invention provides containers and methods of use for the storage, transportation and preparation of samples, such as DNA samples for analysis. The container is pre-provided with the reagents in sealed chambers. The sample can be introduced and the container manipulated to release the reagents, provide the necessary conditions and give a fully prepared sample. The container can then be engaged with an analysis device to identify characteristics of the sample or perform other operations thereon.Type: ApplicationFiled: May 13, 2013Publication date: November 28, 2013Applicants: GRID XITEK LIMITED, FORENSIC SCIENCE SERVICE LIMITEDInventors: Gary ROSS, Sebastian WETHERALL, Owen EVANS, Andrew HOPWOOD, Nina MORAN
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Publication number: 20130210163Abstract: A method for collecting a sample and/or analysing a sample is provided, together with kits for use therein, in which the method includes using the kit and wherein an identifier is provided on one or more of the devices and/or containers and/or packaging which can be recorded and which is used to link the identity of the identifier for one or more of those identifiers to one or more of the identities for one or more of the other identifiers. In this way, the different devices, containers, pieces of equipment, reagents and stages used in the collection and/or analysis can be linked together for future reference. This ensures the correct processing of the sample and the correct attributing of the end results to it. Checks or other enquiries can be made on each of the different devices etc to validate the results if necessary.Type: ApplicationFiled: August 24, 2011Publication date: August 15, 2013Applicants: The Arizona Board of Regents Acting for and on behalf of University of Arizona, FORENSIC SCIENCE SERVICE LIMITEDInventors: Andrew Hopwood, Nina Moran, Pieris Koumi, John Lee-Edghill
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Publication number: 20130130365Abstract: A method of analysis, instrument for analysis and device for use in such an instrument are provided, which perform a number of processes need to reach a useful result in the context of a wide variety of samples. The sequence of those processes being optimised. A device, instrument using the device and method of use are also provided which offer reliable performance of a heating based process, with minimal condensation and/or sample loss issues.Type: ApplicationFiled: October 11, 2012Publication date: May 23, 2013Inventors: Frederic ZENHAUSERN, Alan NORDQUIST, Ralf LENIGK, Cedric HURTH, Jianing YANG, Xiaojia CHEN, Matthew ESTES, John LEE-EDGHILL, Nina MORAN, Andrew HOPWOOD, Pieris KOUMI
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Publication number: 20120183956Abstract: The invention provides containers and methods of use for the storage, transportation and preparation of samples, such as DNA samples for analysis. The container is pre-provided with the reagents in sealed chambers. The sample can be introduced and the container manipulated to release the reagents, provide the necessary conditions and give a fully prepared sample. The container can then be engaged with an analysis device to identify characteristics of the sample or perform other operations thereon.Type: ApplicationFiled: August 10, 2010Publication date: July 19, 2012Applicants: Grid Xitek Limited, Forensic Science Service LimitedInventors: Gary Ross, Sebastian Wetherall, Owen Evans, Andrew Hopwood, Nina Moran
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Publication number: 20110100101Abstract: Instruments, devices and methods of analysis are provided which fully integrate a significant number of process steps in a continuous operation. Accurate positioning and full contact between components is also provided by the relative movement the designs allow. An effect interface between a low cost disposable cartridge or device and the instrument to process it is also detailed.Type: ApplicationFiled: February 9, 2010Publication date: May 5, 2011Inventors: Frederic Zenhausern, Alan Nordquist, Ralf Lenigk, Cedric Hurth, Jianing Yang, Xiaojia Chen, John Lee-Edghill, Nina Moran, Andrew Hopwood, Pieris Koumi
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Publication number: 20100267092Abstract: A method and device structure are provided which enable an archive sample to be collected and detached relative to a device within which a series of processes, such as PCR are being provided. A chamber structure and method of use are provided in which a controlled and precise volume is obtained by control of the relative resistance to flow through various channels.Type: ApplicationFiled: February 9, 2010Publication date: October 21, 2010Inventors: Frederic ZENHAUSERN, Alan Nordquist, Ralf Lenigk, Cedric Hurth, Jianing Yang, Xiaojia Chen, Matthew Estes, John Lee-Edghill, Nina Moran, Andrew Hopwood, Pieris Koumi, Zhi Cai