Patents by Inventor Nina Schneider

Nina Schneider has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PREPARATION OF BETA-AMINO ACIDS
    Publication number: 20120270280
    Abstract: The present invention relates to a process for the biocatalytic, enantioselective production of a ?-amino acid pre-cursor from an optionally substituted dihydrouracil using a hydantoinase and/or a dihydropyrimidinase, a process for producing a ?-amino acid from said precursor, a hydantoinase and its use in said process for the biocatalytic production of a ?-amino acid pre-cursor or a ?-amino acid, and a method for obtaining said hydantoinase.
    Type: Application
    Filed: September 15, 2010
    Publication date: October 25, 2012
    Applicant: BASF SE
    Inventors: Nina Schneider, Bernhard Hauer, Klaus Ditrich, Maeve O'Neil, Nick Turner
  • PROCESS FOR PREPARING N-HETEROCYCLIC OPTICALLY ACTIVE ALCOHOLS
    Publication number: 20120135476
    Abstract: Process for preparing N-heterocyclic optically active alcohols of the formula I by reduction of the corresponding ketone, where the reduction is carried out using a dehydrogenase having the polypeptide sequence SEQ ID NO:2 or NO:4, or using a polypeptide sequence where, compared to SEQ ID NO:2 or NO:4, up to 25% of the amino acid residues are modified by deletion; insertion, substitution or a combination thereof.
    Type: Application
    Filed: November 23, 2011
    Publication date: May 31, 2012
    Applicant: BASF SE
    Inventors: NINA SCHNEIDER, MELANIE BONNEKESSEL, MICHAEL BREUER, JÜRGEN DÄUWEL, KLAUS DITRICH, ULRICH KARL, TOBIAS STÄB
  • BIOCATALYST FOR CATALYTIC HYDROAMINATION
    Publication number: 20120123155
    Abstract: The present invention relates to a method for the enzymatic hydroamination of C—C double bonds catalyzed by enzymes structurally and/or functionally related to phenylalanine ammonia lyase (PAL) isolated from microorganisms of Petroselinum crispum, Rhodoturula glutinis and/or functional active derivatives thereof.
    Type: Application
    Filed: July 27, 2010
    Publication date: May 17, 2012
    Applicant: BASF SE
    Inventors: Bernhard Hauer, Nina Schneider, Dejana Drew, Klaus Ditrich, Nick Turner, Bettina M. Nestl
  • Biocatalysts For Manufacturing Duloxetine Alcohol
    Publication number: 20110250655
    Abstract: The present invention relates to novel phenylethanol dehydrogenase mutants, to a method for the manufacture thereof; to coded nucleic acid sequences therefor, to expression cassettes, to vectors and recombinant microorganisms that contain said sequences; to a method for the biocatalytic synthesis of substituted, optically active alcohols and to the use of said mutants; and particularly to a method for manufacturing duloxetine alcohol or duloxetine, comprising a synthesis step catalyzed biocatalytic by said mutants.
    Type: Application
    Filed: December 16, 2009
    Publication date: October 13, 2011
    Applicant: BASF SE
    Inventors: Nina Schneider, Hans Wolfgang Höffken
  • MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS
    Publication number: 20100311037
    Abstract: The present invention relates to a method for the enzymatic decarboxylation of malonic acid (propanedioic acid) derivatives catalyzed by enzymes structurally and/or functionally related to arylmalonate decarboxylase (AMDase) as isolated from microorganisms of the genus Bordetella. The present invention also relates to novel enzymes with a decarboxylase activity, useful for performing the claimed method, mutants thereof, corresponding coding sequences and expression systems, methods of preparing said novel enzymes, and screening methods for obtaining further suitable enzymes also having said decarboxylase activity.
    Type: Application
    Filed: November 28, 2008
    Publication date: December 9, 2010
    Applicant: Basf SE
    Inventors: Bernhard Hauer, Nina Schneider, Krzysztof Okrasa, Jason Micklefield, David Leys, Colin Levy