Patents by Inventor Nina T. Nguyen

Nina T. Nguyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 14-3-3 Zeta over-expression as a poor prognosis factor, and a therapeutic target in multiple cancer type
    Patent number: 7709205
    Abstract: Methods of determining prognosis in a subject with a hyperproliferative disease, including determining expression and/or function of 14-3-3 zeta in the subject, are disclosed. Also disclosed are methods of making a pharmaceutical agent that modulates apoptosis, including the steps of obtaining one or more candidate, testing the one or more candidate substances to determine their ability to modulate the expression and/or function of 14-3-3 zeta, selecting a candidate substance determined to modulate the expression and/or function of 14-3-3 zeta, and making a pharmaceutical composition that includes the selected candidate substance. In addition, methods of treating a subject with a hyperproliferative disease, including making a pharmaceutical agent by the methods set forth herein, and administering the pharmaceutical agent to a subject, are disclosed. The hyperproliferative disease can be cancer, such as breast cancer.
    Type: Grant
    Filed: December 4, 2007
    Date of Patent: May 4, 2010
    Assignee: Board of Regents, The University of Texas System
    Inventors: Dihua Yu, Jun Yao, Christopher L. Neal, Wentao Yang, Xiaoyan Zhou, Raphael E. Pollock, Mien-Chie Hung, Jun Yang, Ping Li, Nina T. Nguyen
  • 14-3-3 ZETA OVER-EXPRESSION AS A POOR PROGNOSIS FACTOR, AND A THERAPEUTIC TARGET IN MULTIPLE CANCER TYPE
    Publication number: 20080318231
    Abstract: Methods of determining prognosis in a subject with a hyperproliferative disease, including determining expression and/or function of 14-3-3 zeta in the subject, are disclosed. Also disclosed are methods of making a pharmaceutical agent that modulates apoptosis, including the steps of obtaining one or more candidate, testing the one or more candidate substances to determine their ability to modulate the expression and/or function of 14-3-3 zeta, selecting a candidate substance determined to modulate the expression and/or function of 14-3-3 zeta, and making a pharmaceutical composition that includes the selected candidate substance. In addition, methods of treating a subject with a hyperproliferative disease, including making a pharmaceutical agent by the methods set forth herein, and administering the pharmaceutical agent to a subject, are disclosed. The hyperproliferative disease can be cancer, such as breast cancer.
    Type: Application
    Filed: December 4, 2007
    Publication date: December 25, 2008
    Inventors: DIHUA YU, Jun Yao, Christopher L. Neal, Wentao Yang, Xiaoyan Zhou, Raphael E. Pollock, Mien-Chie Hung, Jun Yang, Ping Li, Nina T. Nguyen
  • 14-3-3 zeta over-expression as a poor prognosis factor, and a therapeutic target in multiple cancer types
    Patent number: 7316907
    Abstract: Methods of determining prognosis in a subject with a hyperproliferative disease, including determining expression and/or function of 14-3-3 zeta in the subject, are disclosed. Also disclosed are methods of making a pharmaceutical agent that modulates apoptosis, including the steps of obtaining one or more candidate, testing the one or more candidate substances to determine their ability to modulate the expression and/or function of 14-3-3 zeta, selecting a candidate substance determined to modulate the expression and/or function of 14-3-3 zeta, and making a pharmaceutical composition that includes the selected candidate substance. In addition, methods of treating a subject with a hyperproliferative disease, including making a pharmaceutical agent by the methods set forth herein, and administering the pharmaceutical agent to a subject, are disclosed. The hyperproliferative disease can be cancer, such as breast cancer.
    Type: Grant
    Filed: September 10, 2004
    Date of Patent: January 8, 2008
    Assignee: Board of Regents, The University of Texas System
    Inventors: Dihua Yu, Jun Yao, Christopher L. Neal, Wentao Yang, Xiaoyan Zhou, Raphael E. Pollock, Mien-Chie Hung, Jun Yang, Ping Li, Nina T. Nguyen