Abstract: The present invention relates to novel pyridazin-3-yl phenol compounds of formula (I): wherein R1, R2, R3, R4 and R5 are defined herein, which inhibit NOD-like receptor protein 3 (NLRP3) inflammasome activity. The invention further relates to the processes for their preparation, pharmaceutical compositions and medicaments containing them, and their use in the treatment of diseases and disorders mediated by NLRP3.

Abstract: The disclosure provides a method for growing a gallium oxide single crystal by casting and a semiconductor device containing the gallium oxide single crystal. The method includes: 1) heating a solid gallium oxide to complete melting, cooling to a melting point of the gallium oxide, and maintaining a melt state for at least 30 min; and 2) conducting gradient cooling on a gallium oxide melt obtained in step 1) until a solid gallium oxide single crystal is obtained. The gradient cooling is to cool the gallium oxide melt obtained in step 1) to a first temperature according to a first gradient, and then continue cooling to a room temperature according to a second gradient to obtain the gallium oxide single crystal. In step 1), since the solid gallium oxide is heated to the first temperature, oxygen with a volume fraction of at least 2% is present in a growth atmosphere.

Abstract: The disclosure provides a method for growing a gallium oxide single crystal by casting and a semiconductor device containing the gallium oxide single crystal. The method includes: 1) heating a solid gallium oxide to complete melting, cooling to a melting point of the gallium oxide, and maintaining a melt state for at least 30 min; and 2) conducting gradient cooling on a gallium oxide melt obtained in step 1) until a solid gallium oxide single crystal is obtained. The gradient cooling is to cool the gallium oxide melt obtained in step 1) to a first temperature according to a first gradient, and then continue cooling to a room temperature according to a second gradient to obtain the gallium oxide single crystal. In step 1), since the solid gallium oxide is heated to the first temperature, oxygen with a volume fraction of at least 2% is present in a growth atmosphere.

Abstract: A device and method for sputtering and depositing metal on the surface of magnetic powder materials utilizes a vacuum chamber, a vacuum pump set, a magnetron sputtering target, a cathode ion source, a water-cooled anode, and a sample holding component arranged in the vacuum chamber. The sample holding component is a sample roller, an axis of the sample roller is arranged in a horizontal direction, the sample roller can rotate around the axis thereof. Two ends of the sample roller are open, and the sample roller further comprises a power device capable of driving the sample roller to rotate. The cathode ion source and the magnetron sputtering target extend inwards into the sample roller from the opening in the same end of the sample roller. The water-cooled anode extends inwards into the sample roller from the opening in the other end of the sample roller.

Abstract: Methods and systems for detecting and correcting anomalies include comparing a new time series segment, generated by a sensor in a cyber-physical system, to previous time series segments of the sensor to generate a similarity measure for each previous time series segment. It is determined that the new time series represents anomalous behavior based on the similarity measures. A corrective action is performed on the cyber-physical system to correct the anomalous behavior.

Abstract: In some examples, device debugging connection control and maintenance may include receiving, from a debug tool, a connection request to connect to a device to be debugged. Based on the connection request, a primary socket connection may be implemented via a Universal Serial Bus (USB) channel to the device. Based on the connection request, a backup socket connection may be implemented via a Wi-Fi channel to the device. Based on the implementation of the primary socket connection and the backup socket connection, maintenance of a debugging session may be controlled during performance of a debugging operation.

Abstract: Implementations of this specification include identifying a plurality of transactions to be executed in the blockchain, wherein the transactions are arranged in an execution order, wherein the transactions include one or more smart contract calls to smart contracts each having a whitelist identifying one or more accounts that are authorized to execute the smart contract, and wherein the execution order includes a smart contract call to a smart contract that does not have a whitelist arranged after the plurality of transactions; identifying groups of transactions within the plurality of transactions; instructing nodes of the blockchain network to execute each of the groups of transactions in parallel; determining that the nodes of the blockchain network have completed executing all of the groups of transactions; and in response, instructing the nodes of the blockchain network to execute the smart contract call that does not include a whitelist.

Abstract: Implementations of this specification include identifying, by a node of the blockchain network, a request to execute a smart contract stored in a blockchain maintained by the blockchain network, the request identifying a requesting account that is requesting to execute the smart contract; retrieving, by the node, a whitelist from the blockchain associated with the smart contract, the whitelist identifying one or more accounts that are authorized to execute the smart contract; determining, by the node, that the requesting account is authorized to execute the smart contract based on the requesting account being included in the whitelist; and in response to determining that the requesting account is authorized to execute the smart contract, executing, by the node, the smart contract.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for parallel-processing blockchain transactions are provided. One of the methods includes: obtaining a plurality of candidate transactions for adding to a blockchain; grouping the candidate transactions into one or more transaction groups; creating one or more copies of at least a portion of a data structure of a latest block of the blockchain; associating the one or more transaction groups respectively with the one or more copies of the data structure; executing the candidate transactions in each of the transaction groups and updating the associated copies of the data structure; and merging the updated copies of the data structure to obtain at least a portion of a new data structure of a new block to add to the blockchain.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for implementing blockchain-based private transactions are provided. One of the methods includes transmitting, at a first blockchain node of a number (N) of blockchain nodes that are involved in a private transaction, the private transaction to each of a plurality of second blockchain nodes of the N blockchain nodes, wherein N is at least four, at least (N?F) signatures certifying the private transaction respectively from at least (N?F) blockchain nodes of the first and second blockchain nodes, wherein F is a largest integer no more than (N?1)/2; and submitting, at the first blockchain node, a hash value of the private transaction in association with the at least (N?F) signatures to one or more blockchain nodes of a public blockchain for adding into the public blockchain.

Abstract: Disclosed herein are methods, systems, and apparatus, including computer programs encoded on computer storage media, for performing parallel execution of transactions by a network node in a blockchain network. One of the methods includes receiving multiple transactions, grouping all first-type transactions in the multiple transactions into a group of first-type transactions, dividing the group of first-type transactions into one or more subgroups, and executing the group of first-type transactions by executing the one or more subgroups of the group of first-type transactions in parallel.

Abstract: Using a blockchain transaction acceleration system, a first transaction generated by a first node is sent to an acceleration node in a blockchain, where the first transaction is sent to the acceleration node instead of being sent directly to a second node that is the intended recipient of the first transaction, and where the first node, the second node, and the acceleration node are different nodes. The blockchain transaction acceleration system forwards the transaction from the acceleration node to the second node. The blockchain transaction acceleration system executes the transaction by the second node.

Abstract: Implementations of this specification include identify a plurality of transactions to be executed in the blockchain, wherein the transactions are arranged in an execution order, and wherein the execution order includes a contract call arranged after the plurality of transactions; identify groups of transactions within the plurality of transactions, wherein each transaction in each group is associated with a same account in the blockchain network as the other transactions in the group; instruct nodes of the blockchain network to execute each of the groups of transactions in parallel, wherein executing each group of transactions includes executing the transactions within the group serially and according to the execution order; determine that the nodes of the blockchain network have completed executing all of the groups of transactions; and in response, instruct the nodes of the blockchain network to execute the contract call.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for implementing blockchain-based private transactions are provided. One of the methods includes transmitting, at a first blockchain node of a number (N) of blockchain nodes that are involved in a private transaction, the private transaction to each of a plurality of second blockchain nodes of the N blockchain nodes, wherein N is at least four, at least (N?F) signatures certifying the private transaction respectively from at least (N?F) blockchain nodes of the first and second blockchain nodes, wherein F is a largest integer no more than (N?1)/2; and submitting, at the first blockchain node, a hash value of the private transaction in association with the at least (N?F) signatures to one or more blockchain nodes of a public blockchain for adding into the public blockchain.

Abstract: Implementations of this specification include identifying, by a node of the blockchain network, a request to execute a smart contract stored in a blockchain maintained by the blockchain network, the request identifying a requesting account that is requesting to execute the smart contract; retrieving, by the node, a whitelist from the blockchain associated with the smart contract, the whitelist identifying one or more accounts that are authorized to execute the smart contract; determining, by the node, that the requesting account is authorized to execute the smart contract based on the requesting account being included in the whitelist; and in response to determining that the requesting account is authorized to execute the smart contract, executing, by the node, the smart contract.

Abstract: Disclosed herein are methods, systems, and apparatus, including computer programs encoded on computer storage media, for performing parallel execution of transactions by a network node in a blockchain network. One of the methods includes receiving multiple transactions, grouping all first-type transactions in the multiple transactions into a group of first-type transactions, dividing the group of first-type transactions into one or more subgroups, and executing the group of first-type transactions by executing the one or more subgroups of the group of first-type transactions in parallel.

Abstract: In a blockchain transaction acceleration system, receive a first transaction sent through a first node in a blockchain. At least one second transaction that is a duplicate of the first transaction is received in the blockchain transaction acceleration system, where the at least one second transaction sent by the first node to at least one second node in the blockchain is different from the first node. The blockchain transaction acceleration system executes a first-received transaction among received transactions that include the first transaction and the at least one second transaction. Upon determining, by the blockchain transaction acceleration system, that remaining transactions of the received transactions are identical to the first-received transaction, discarding the remaining transactions.

Abstract: In a blockchain transaction acceleration system, receive a first transaction sent through a first node in a blockchain. At least one second transaction that is a duplicate of the first transaction is received in the blockchain transaction acceleration system, where the at least one second transaction sent by the first node to at least one second node in the blockchain is different from the first node. The blockchain transaction acceleration system executes a first-received transaction among received transactions that include the first transaction and the at least one second transaction. Upon determining, by the blockchain transaction acceleration system, that remaining transactions of the received transactions are identical to the first-received transaction, discarding the remaining transactions.

Abstract: Implementations of this specification include identifying, by a node of the blockchain network, a request to execute a smart contract stored in a blockchain maintained by the blockchain network, the request identifying a requesting account that is requesting to execute the smart contract; retrieving, by the node, a whitelist from the blockchain associated with the smart contract, the whitelist identifying one or more accounts that are authorized to execute the smart contract; determining, by the node, that the requesting account is authorized to execute the smart contract based on the requesting account being included in the whitelist; and in response to determining that the requesting account is authorized to execute the smart contract, executing, by the node, the smart contract.

Abstract: Using a blockchain transaction acceleration system, a first transaction generated by a first node is sent to an acceleration node in a blockchain, where the first transaction is sent to the acceleration node instead of being sent directly to a second node that is the intended recipient of the first transaction, and where the first node, the second node, and the acceleration node are different nodes. The blockchain transaction acceleration system forwards the transaction from the acceleration node to the second node. The blockchain transaction acceleration system executes the transaction by the second node.