Patents by Inventor Ning Zou

Ning Zou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hole protection system and method for coal seam slotting and fracturing combined drainage
    Patent number: 11970945
    Abstract: A hole protection system and a method for coal seam slotting and fracturing combined drainage. The system includes a hydraulic slotting subsystem, a hydraulic fracturing subsystem and a flexible hole protection system. The hydraulic slotting subsystem includes an ultra-high pressure water jet generating module, a drill pipe drilling tool module, an orifice sealer, a gas slag separator and a drilling rig. The hydraulic fracturing system includes an emulsion pump station, a water tank, a hole sealing device, a fracturing string and a casing. The flexible hole protection system includes a front end fixing device, a water injection support pipe, a first flexible support and a water injection connecting section.
    Type: Grant
    Filed: March 17, 2023
    Date of Patent: April 30, 2024
    Assignees: Hancheng Zaozhuang Industrial Co., Ltd., Chongqing University
    Inventors: Xiaoyan Sun, Quanle Zou, Qican Ran, Peimiao Sang, Jinyan Liang, Ning Li, Wei Pi
  • MULTIFUNCTIONAL MIXED OXIDE ELECTROCATALYST MATERIAL AND PREPARATION METHOD AND USE THEREOF
    Publication number: 20240079604
    Abstract: A multifunctional mixed oxide electrocatalyst material including a metal oxide A with oxygen storage capacity and a metal oxide B with oxygen evolution reaction is prepared by two-steps hydrothermal reactions. The electrocatalyst material is a good free radical scavenger, oxygen evolution reagent and able to alleviate carbon monoxide poisoning on catalyst, when it is applied in a membrane electrode assembly for fuel cells.
    Type: Application
    Filed: September 7, 2022
    Publication date: March 7, 2024
    Inventors: Hongliang AO, Yunsong YANG, Yun CAI, Siyu YE, Yuquan ZOU, Junke TANG, Ning SUN
  • MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
    Publication number: 20230404954
    Abstract: The present invention relates to amide derivatives of Formula (XIIIa) and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Application
    Filed: April 28, 2023
    Publication date: December 21, 2023
    Inventors: Thuy-Anh TRAN, Weichao CHEN, Bryan A. KRAMER, Abu J.M. SADEQUE, Anna SHIFRINA, Young-Jun SHIN, Pureza VALLAR, Ning ZOU
  • MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
    Publication number: 20230121825
    Abstract: The present invention relates to amide derivatives of Formula (XIIIa) and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Application
    Filed: June 7, 2022
    Publication date: April 20, 2023
    Inventors: Thuy-Anh TRAN, Weichao CHEN, Bryan A. KRAMER, Abu J.M. SADEQUE, Anna SHIFRINA, Young-Jun SHIN, Pureza VALLAR, Ning ZOU
  • SELECTIVE DELIVERY OF THERAPEUTIC AND IMAGING AGENTS
    Publication number: 20220347306
    Abstract: Described herein are methods and compositions for the targeted delivery of selective delivery molecule therapeutic agents and imaging agents.
    Type: Application
    Filed: April 16, 2019
    Publication date: November 3, 2022
    Inventors: Jesus E. GONZALEZ, Junjie LIU, Marcel MIAMPAMBA, Ning ZOU, Andrew GALE
  • Pyrazolyl substituted carbonic acid derivatives as modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto
    Patent number: 11098034
    Abstract: Pyrazole derivatives of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Grant
    Filed: April 30, 2020
    Date of Patent: August 24, 2021
    Assignee: ARENA PHARMACEUTICALS, INC.
    Inventors: Thuy-Anh Tran, Jason B. Ibarra, Young-Jun Shin, Brett Ullman, Ning Zou, Xi Zeng
  • COMPOSITIONS AND METHODS FOR THE SELECTIVE DELIVERY OF THERAPEUTIC AND IMAGING AGENTS
    Publication number: 20210079039
    Abstract: Described herein are methods and compositions for the targeted delivery of therapeutic agents and imaging agents.
    Type: Application
    Filed: April 16, 2019
    Publication date: March 18, 2021
    Inventors: Jesus E. GONZALEZ, Junjie LIU, Marcel MIAMPAMBA, Giuseppe DELLO IACANO, Ning ZOU, Andrew GALE
  • PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
    Publication number: 20200392123
    Abstract: Pyrazole derivatives of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Application
    Filed: April 30, 2020
    Publication date: December 17, 2020
    Inventors: Thuy-Anh TRAN, Jason B. IBARRA, Young-Jun SHIN, Brett ULLMAN, Ning ZOU, Xi ZENG
  • SUBSTITUTED PYRIDAZINES AND 1,2,4-TRIAZINES AS PROSTACYCLIN RECEPTOR MODULATORS
    Publication number: 20200385357
    Abstract: Cyclohexane derivatives of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Application
    Filed: August 25, 2020
    Publication date: December 10, 2020
    Inventors: Thuy-Anh TRAN, Rena HAYASHI, Jason B. IBARRA, Brett ULLMAN, Ning ZOU
  • MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
    Publication number: 20200375930
    Abstract: The present invention relates to amide derivatives of Formula (XIIIa) and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Application
    Filed: April 14, 2020
    Publication date: December 3, 2020
    Inventors: Thuy-Anh TRAN, Weichao CHEN, Bryan A. KRAMER, Abu J.M. SADEQUE, Anna SHIFRINA, Young-Jun SHIN, Pureza VALLAR, Ning ZOU
  • PBD CONJUGATES FOR TREATING DISEASES
    Publication number: 20200323991
    Abstract: The present disclosure relates to pyrrolobenzodiazepine (PBD) prodrugs and conjugates thereof. The present disclosure also relates to pharmaceutical compositions of the conjugates described herein, methods of making and methods of using the same.
    Type: Application
    Filed: March 29, 2017
    Publication date: October 15, 2020
    Inventors: Iontcho Radoslavov VLAHOV, Christopher Paul LEAMON, Longwu QI, Ning ZOU, Kevin Yu WANG, Albert E. FELTEN, Garth L. PARHAM, Fei YOU, Hari Krishna R. SANTHAPURAM, Spencer J. HAHN, Joseph Anand REDDY, Yingjuan J. LU, Leroy W. WHEELER, II
  • Substituted pyridazines and 1,2,4-triazines as prostacyclin receptor modulators
    Patent number: 10793529
    Abstract: Cyclohexane derivatives of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: October 6, 2020
    Assignee: ARENA PHARMACEUTICALS, INC.
    Inventors: Thuy-Anh Tran, Rena Hayashi, Jason B. Ibarra, Brett Ullman, Ning Zou
  • CONJUGATES FOR TREATING DISEASES
    Publication number: 20200289659
    Abstract: The present disclosure relates to pyrrolobenzodiazepine (PBD) prodrugs and conjugates thereof. The present disclosure also relates to pharmaceutical compositions of the conjugates described herein, methods of making and methods of using the same.
    Type: Application
    Filed: March 20, 2020
    Publication date: September 17, 2020
    Inventors: Iontcho Radoslavov Vlahov, Christopher Paul Leamon, Longwu QI, Yingcai Wang, Kevin Yu Wang, Ning Zou, Albert E. Felten
  • Pyrazolyl substituted carbonic acid derivatives as modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto
    Patent number: 10689372
    Abstract: Pyrazole derivatives of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: June 23, 2020
    Assignee: ARENA PHARMACEUTICALS, INC.
    Inventors: Thuy-Anh Tran, Jason B. Ibarra, Young-Jun Shin, Brett Ullman, Ning Zou, Xi Zeng
  • Modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto
    Patent number: 10668033
    Abstract: The present invention relates to amide derivatives of Formula (XIIIa) and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: June 2, 2020
    Assignee: ARENA PHARMACEUTICALS, INC.
    Inventors: Thuy-Anh Tran, Weichao Chen, Bryan A. Kramer, Abu J. M. Sadeque, Anna Shifrina, Young-Jun Shin, Pureza Vallar, Ning Zou
  • Conjugates for treating diseases
    Patent number: 10624972
    Abstract: The present disclosure relates to pyrrolobenzodiazepine (PBD) prodrugs and conjugates thereof. The present disclosure also relates to pharmaceutical compositions of the conjugates described herein, methods of making and methods of using the same.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: April 21, 2020
    Assignee: Endocyte, Inc.
    Inventors: Iontcho Radoslavov Vlahov, Christopher Paul Leamon, Longwu Qi, Yingcai Wang, Kevin Yu Wang, Ning Zou, Albert E. Felten
  • FOLATE CONJUGATE FOR USE IN TARGETING TUMOR ASSOCIATED MACROPHAGES
    Publication number: 20200038514
    Abstract: Methods are provided for treating cancers using a conjugate herein described as Conjugate 5, or a pharmaceutically acceptable salt thereof. Methods for treating cancers using Conjugate 5, or a pharmaceutically acceptable salt thereof, to target tumor associated macrophages are also described.
    Type: Application
    Filed: September 14, 2017
    Publication date: February 6, 2020
    Inventors: Iontcho Radoslavov VLAHOV, Christopher Paul LEAMON, Longwu QI, Ning ZOU, Kevin Yu WANG, Albert E. FELTEN, Garth L. PARHAM, Fei YOU, Hari Krishna R. SANTHAPURAM, Spencer J. HAHN, Joseph Anand REDDY, Yingjuan J. LU, Leroy W. WHEELER, II
  • PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
    Publication number: 20190270731
    Abstract: Pyrazole derivatives of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Application
    Filed: November 6, 2018
    Publication date: September 5, 2019
    Inventors: Thuy-Anh Tran, Jason B. Ibarra, Young-Jun Shin, Brett Ullman, Ning Zou, Xi Zeng
  • MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
    Publication number: 20190248749
    Abstract: Cyclohexane derivatives of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Application
    Filed: October 15, 2018
    Publication date: August 15, 2019
    Inventors: Thuy-Anh Tran, Rena Hayashi, Jason B. Ibarra, Brett Ullman, Ning Zou
  • Method, apparatus and system for using a user equipment as a small evolved NodeB for a small cell
    Patent number: 10244083
    Abstract: A device, method and system of using a first user equipment (UE) as a small evolved NodeB (eNB) for a small cell may comprise receiving a first long term evolution (LTE) packet from a second UE over the small cell; converting the first LTE packet into a first transmission control protocol/Internet protocol (TCP/IP) packet, wherein the converting includes retrieving payload data from the first LTE packet and encapsulating the payload data into the first TCP/IP packet by adding a TCP/IP header to the payload data, and wherein the TCP/IP header includes an IP address of an Evolved Packet Core (EPC) network associated to Internet based on a TCP/IP tunneling protocol; and transmitting the first TCP/IP packet to an Internet destination via the EPC connected with the first UE through an Internet server over a local area network (LAN).
    Type: Grant
    Filed: October 16, 2014
    Date of Patent: March 26, 2019
    Assignee: Intel Corporation
    Inventors: Yuan Zhu, Yuan Zhang, Yinhui Liu, Ning Zou