Patents by Inventor Ninghui Yu

Ninghui Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphorus imidazoquinoline amine derivatives, pharmaceutical compositions and therapeutic methods thereof
    Patent number: 11932663
    Abstract: The invention provides novel phosphorus imidazoquinoline amine derivatives, having agonistic activities to Toll-like receptors (TLRs), in particular TLR7 and/or TLR8, pharmaceutical compositions thereof, and methods of treatment, reduction or prevention of certain diseases or conditions mediated by or associated with TLR7 and/or TLR8, e.g., cancer, graft rejection, autoimmunity, inflammation allergy, asthma, infection, sepsis, and immunodeficiency.
    Type: Grant
    Filed: August 19, 2022
    Date of Patent: March 19, 2024
    Assignee: CanWell Biotech Limited
    Inventor: Ninghui Yu
  • PREPARATION AND USE OF ANTI-FSHR ANTIBODY AND ANTIBODY-DRUG CONJUGATE THEREOF
    Publication number: 20240043548
    Abstract: The preparation and use of an anti-F SHR antibody and an antibody-drug conjugate thereof. Specifically, an antibody or an antigen-binding fragment thereof is disclosed. The antibody or the antigen-binding fragment thereof contains a variable region and specifically binds to human follicle-stimulating hormone receptor FSEIR, and contains one, two, three, four, five or six CDRs with the following amino acid sequences shown in SEQ ID NOs: 6, 7, 8, 10, 11 and 12.
    Type: Application
    Filed: November 18, 2021
    Publication date: February 8, 2024
    Applicant: CANWELL (GZ) BIOTECH LIMITED
    Inventors: Ninghui YU, Xuliang JIANG
  • PHOSPHORUS IMIDAZOQUINOLINE AMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS THEREOF
    Publication number: 20230126473
    Abstract: The invention provides novel phosphorus imidazoquinoline amine derivatives, having agonistic activities to Toll-like receptors (TLRs), in particular TLR7 and/or TLR8, pharmaceutical compositions thereof, and methods of treatment, reduction or prevention of certain diseases or conditions mediated by or associated with TLR7 and/or TLR8, e.g., cancer, graft rejection, autoimmunity, inflammation allergy, asthma, infection, sepsis, and immunodeficiency.
    Type: Application
    Filed: August 19, 2022
    Publication date: April 27, 2023
    Inventor: Ninghui Yu
  • Phosphorus imidazoquinoline amine derivatives, pharmaceutical compositions and therapeutic methods thereof
    Patent number: 11453688
    Abstract: The invention provides novel phosphorus imidazoquinoline amine derivatives, having agonistic activities to Toll-like receptors (TLRs), in particular TLR7 and/or TLR8, pharmaceutical compositions thereof, and methods of treatment, reduction or prevention of certain diseases or conditions mediated by or associated with TLR7 and/or TLR8, e.g., cancer, graft rejection, autoimmunity, inflammation allergy, asthma, infection, sepsis, and immunodeficiency.
    Type: Grant
    Filed: January 9, 2021
    Date of Patent: September 27, 2022
    Assignee: CANWELL BIOTECH LIMITED
    Inventor: Ninghui Yu
  • PHOSPHORUS IMIDAZOQUINOLINE AMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS THEREOF
    Publication number: 20210253613
    Abstract: The invention provides novel phosphorus imidazoquinoline amine derivatives, having agonistic activities to Toll-like receptors (TLRs), in particular TLR7 and/or TLR8, pharmaceutical compositions thereof, and methods of treatment, reduction or prevention of certain diseases or conditions mediated by or associated with TLR7 and/or TLR8, e.g., cancer, graft rejection, autoimmunity, inflammation allergy, asthma, infection, sepsis, and immunodeficiency.
    Type: Application
    Filed: January 9, 2021
    Publication date: August 19, 2021
    Inventor: Ninghui Yu
  • IMIDAZOQUINOLINE AMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS THEREOF
    Publication number: 20210163477
    Abstract: The invention provides novel imidazoquinoline amine derivatives, having agonistic activities to Toll-like receptors (TLRs), in particular TLR7 and/or TLR8, pharmaceutical compositions thereof, and methods of treatment, reduction or prevention of certain diseases or conditions mediated by or associated with TLR7 and/or TLR8, e.g., graft rejection, autoimmunity, inflammation allergy, asthma, infection, sepsis, cancer and immunodeficiency.
    Type: Application
    Filed: February 17, 2021
    Publication date: June 3, 2021
    Inventor: Ninghui Yu
  • Imidazoquinoline amine derivatives, pharmaceutical compositions and therapeutic methods thereof
    Patent number: 10954239
    Abstract: The invention provides novel imidazoquinoline amine derivatives, having agonistic activities to Toll-like receptors (TLRs), in particular TLR7 and/or TLR8, pharmaceutical compositions thereof, and methods of treatment, reduction or prevention of certain diseases or conditions mediated by or associated with TLR7 and/or TLR8, e.g., graft rejection, autoimmunity, inflammation allergy, asthma, infection, sepsis, cancer and immunodeficiency.
    Type: Grant
    Filed: September 14, 2020
    Date of Patent: March 23, 2021
    Assignee: CanWell Biotech Limited
    Inventor: Ninghui Yu
  • Phosphorus imidazoquinoline amine derivatives, pharmaceutical compositions and therapeutic methods thereof
    Patent number: 10906923
    Abstract: The invention provides novel phosphorus imidazoquinoline amine derivatives, having agonistic activities to Toll-like receptors (TLRs), in particular TLR7 and/or TLR8, pharmaceutical compositions thereof, and methods of treatment, reduction or prevention of certain diseases or conditions mediated by or associated with TLR7 and/or TLRS, e.g., cancer, graft rejection, autoimmunity, inflammation allergy, asthma, infection, sepsis, and immunodeficiency.
    Type: Grant
    Filed: January 28, 2020
    Date of Patent: February 2, 2021
    Assignee: CanWell Biotech Limited
    Inventor: Ninghui Yu
  • PHOSPHORUS IMIDAZOQUINOLINE AMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS THEREOF
    Publication number: 20210009612
    Abstract: The invention provides novel phosphorus imidazoquinoline amine derivatives, having agonistic activities to Toll-like receptors (TLRs), in particular TLR7 and/or TLR8, pharmaceutical compositions thereof, and methods of treatment, reduction or prevention of certain diseases or conditions mediated by or associated with TLR7 and/or TLRS, e.g., cancer, graft rejection, autoimmunity, inflammation allergy, asthma, infection, sepsis, and immunodeficiency.
    Type: Application
    Filed: January 28, 2020
    Publication date: January 14, 2021
    Inventor: Ninghui Yu
  • IMIDAZOQUINOLINE AMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS THEREOF
    Publication number: 20200407358
    Abstract: The invention provides novel imidazoquinoline amine derivatives, having agonistic activities to Toll-like receptors (TLRs), in particular TLR7 and/or TLR8, pharmaceutical compositions thereof, and methods of treatment, reduction or prevention of certain diseases or conditions mediated by or associated with TLR7 and/or TLR8, e.g., graft rejection, autoimmunity, inflammation allergy, asthma, infection, sepsis, cancer and immunodeficiency.
    Type: Application
    Filed: September 14, 2020
    Publication date: December 31, 2020
    Inventor: Ninghui Yu