Patents by Inventor Ningning Miao

Ningning Miao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating dopaminergic and GABA-nergic disorders
    Publication number: 20070048286
    Abstract: It is shown here that hedgehog proteins possess novel activities beyond phenotype specification. Using cultures derived from the embryonic day 14.5 (E14.5) rat ventral mesencephalon, we show that hedgehog is also trophic for dopaminergic neurons. Interestingly, hedgehog not only promotes dopaminergic neuron survival, but also promotes the survival of midbrain GABA-immunoreactive (GABA-ir) neurons.
    Type: Application
    Filed: October 25, 2006
    Publication date: March 1, 2007
    Inventors: Ningning Miao, Monica Wang, Nagesh Mahanthappa, Ping Jin, Kevin Pang
  • Vertebrate embryonic patterning-inducing proteins, compositions and uses related therto
    Patent number: 7144997
    Abstract: It is shown here that hedgehog proteins possess novel activities beyond phenotype specification. Using cultures derived from the embryonic day 14.5 (E14.5) rat ventral mesencephalon, we show that hedgehog is also trophic for dopaminergic neurons. Interestingly, hedgehog not only promotes dopaminergic neuron survival, but also promotes the survival of midbrain GABA-immunoreactive (GABA-ir) neurons.
    Type: Grant
    Filed: July 24, 1997
    Date of Patent: December 5, 2006
    Assignee: Curis, Inc.
    Inventors: Ningning Miao, Monica Wang, Nagesh K. Mahanthappa, Kevin Pang
  • Method of treating dopaminergic and GABA-nergic disorders
    Patent number: 7138492
    Abstract: It is shown here that hedgehog proteins possess novel activities beyond phenotype specification. Using cultures derived from the embryonic day 14.5 (E14.5) rat ventral mesencephalon, we show that hedgehog is also trophic for dopaminergic neurons. Interestingly, hedgehog not only promotes dopaminergic neuron survival, but also promotes the survival of midbrain GABA-immunoreactive (GABA-ir) neurons.
    Type: Grant
    Filed: December 1, 1999
    Date of Patent: November 21, 2006
    Assignee: Curis, Inc.
    Inventors: Ningning Miao, Monica Wang, Nagesh K. Mahanthappa, Ping Jin, Kevin Pang
  • METHOD OF TREATING DOPAMINERGIC AND GABA-NERGIC DISORDERS
    Publication number: 20030119729
    Abstract: It is shown here that hedgehog proteins possess novel activities beyond phenotype specification. Using cultures derived from the embryonic day 14.5 (E14.5) rat ventral mesencephalon, we show that hedgehog is also trophic for dopaminergic neurons. Interestingly, hedgehog not only promotes dopaminergic neuron survival, but also promotes the survival of midbrain GABA-immunoreactive (GABA-ir) neurons.
    Type: Application
    Filed: December 1, 1999
    Publication date: June 26, 2003
    Inventors: NINGNING MIAO, MONICA WANG, NAGESH K. MAHANTHAPPA, PING JIN, KEVIN PANG
  • VERTEBRATE EMBRYONIC PATTERNING-INDUCING PROTEINS, COMPOSITIONS AND USES RELATED THERTO
    Publication number: 20020045206
    Abstract: It is shown here that hedgehog proteins possess novel activities beyond phenotype specification. Using cultures derived from the embryonic day 14.5 (E14.5) rat ventral mesencephalon, we show that hedgehog is also trophic for dopaminergic neurons. Interestingly, hedgehog not only promotes dopaminergic neuron survival, but also promotes the survival of midbrain GABA-immunoeractive (GABA-ir) neurons.
    Type: Application
    Filed: July 24, 1997
    Publication date: April 18, 2002
    Inventors: NINGNING MIAO, MONICA WANG, NAGESH K. MAHANTHAPPA, KEVIN PANG