Patents by Inventor Nini Kjus
Nini Kjus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11261480Abstract: A method for processing a nucleic acid, in which the nucleic acid is exposed to an aqueous medium which includes a polyol in sufficient proportion for at least a portion of the nucleic acid to enter or remain in an extra-solution phase. Thus, a polyol may be used to bind a nucleic acid which is in solution to a solid support or to wash a nucleic acid on a solid support whilst maintaining it on the support. The polyol may for example be a C2-C10 alkanediol.Type: GrantFiled: April 15, 2020Date of Patent: March 1, 2022Assignee: Life Technologies ASInventors: Darren Ellis, Geir Fonnum, Nini Kjus
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Publication number: 20200308630Abstract: A method for processing a nucleic acid, in which the nucleic acid is exposed to an aqueous medium which includes a polyol in sufficient proportion for at least a portion of the nucleic acid to enter or remain in an extra-solution phase. Thus, a polyol may be used to bind a nucleic acid which is in solution to a solid support or to wash a nucleic acid on a solid support whilst maintaining it on the support. The polyol may for example be a C2-C10 alkanediol.Type: ApplicationFiled: April 15, 2020Publication date: October 1, 2020Inventors: Darren Ellis, Geir Fonnum, Nini Kjus
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Publication number: 20190233558Abstract: A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.Type: ApplicationFiled: January 28, 2019Publication date: August 1, 2019Applicant: LIFE TECHNOLOGIES ASInventors: Geir FONNUM, Grete Irene MODAHL, Nini KJUS, Astrid Evenroed MOLTEBERG, Diem Thuy Thi TRAN, Jo AASERUD, Muhammed GOKMEN, Steven M. MENCHEN, Carl FULLER, Luisa ANDRUZZI, Wolfgang HINZ
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Patent number: 10017586Abstract: This invention relates to monodisperse cross-linked polymer particles, comprising particles with a substantially smooth outer surface and an average diameter of less than 1 ?m, wherein the particles are solid or porous, and wherein the coefficient of variation (CV) % of the particles, when measured by CPS disk centrifugation analysis, is less than 15%. These monodisperse cross-linked polymer particles may comprise magnetic material and are useful in various application. This invention also relates to monodisperse polymer particles for use as seed particles in the Ugelstad process.Type: GrantFiled: March 8, 2017Date of Patent: July 10, 2018Assignee: LIFE TECHNOLOGIES ASInventors: Grete Modahl, Geir Fonnum, Astrid Molteberg, Silje Lien, Nini Kjus
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Publication number: 20180163255Abstract: A method for processing a nucleic acid, in which the nucleic acid is exposed to an aqueous medium which includes a polyol in sufficient proportion for at least a portion of the nucleic acid to enter or remain in an extra-solution phase. Thus, a polyol may be used to bind a nucleic acid which is in solution to a solid support or to wash a nucleic acid on a solid support whilst maintaining it on the support. The polyol may for example be a C2-C10 alkanediol.Type: ApplicationFiled: February 8, 2018Publication date: June 14, 2018Inventors: Darren ELLIS, Geir FONNUM, Nini KJUS
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Patent number: 9909165Abstract: A method for processing a nucleic acid, in which the nucleic acid is exposed to an aqueous medium which includes a polyol in sufficient proportion for at least a portion of the nucleic acid to enter or remain in an extra-solution phase. Thus, a polyol may be used to bind a nucleic acid which is in solution to a solid support or to wash a nucleic acid on a solid support while maintaining it on the support. The polyol may for example be a C2-C10 alkanediol.Type: GrantFiled: February 13, 2017Date of Patent: March 6, 2018Assignee: Life Technologies CorporationInventors: Darren Ellis, Geir Fonnum, Nini Kjus
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Publication number: 20170218095Abstract: This invention relates to monodisperse cross-linked polymer particles, comprising particles with a substantially smooth outer surface and an average diameter of less than 1 ?m, wherein the particles are solid or porous, and wherein the coefficient of variation (CV) % of the particles, when measured by CPS disk centrifugation analysis, is less than 15%. These monodisperse cross-linked polymer particles may comprise magnetic material and are useful in various application. This invention also relates to monodisperse polymer particles for use as seed particles in the Ugelstad process.Type: ApplicationFiled: March 8, 2017Publication date: August 3, 2017Inventors: Grete MODAHL, Geir FONNUM, Astrid MOLTEBERG, Silje LIEN, Nini KJUS
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Publication number: 20170204398Abstract: A method for processing a nucleic acid, in which the nucleic acid is exposed to an aqueous medium which includes a polyol in sufficient proportion for at least a portion of the nucleic acid to enter or remain in an extra-solution phase. Thus, a polyol may be used to bind a nucleic acid which is in solution to a solid support or to wash a nucleic acid on a solid support whilst maintaining it on the support. The polyol may for example be a C2-C10 alkanediol.Type: ApplicationFiled: February 13, 2017Publication date: July 20, 2017Inventors: Darren ELLIS, Geir FONNUM, Nini KJUS
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Patent number: 9243085Abstract: A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.Type: GrantFiled: February 8, 2013Date of Patent: January 26, 2016Assignees: Life Technologies Corporation, Life Technologies ASInventors: Geir Fonnum, Grete Modahl, Nini Kjus, Astrid Evenroed Molteberg, Diem Tran, Jo Aaserud, M. Talha Gokmen, Steven Menchen, Carl Fuller, Luisa Andruzzi, Wolfgang Hinz
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Patent number: 9062079Abstract: A silyl protected diacrylamide compound is described. A method of forming such a compound includes mixing a silylation reagent with a hydroxylated diamine compound under first reactive conditions to form a product in a first solution, separating the product from the first solution, and mixing the product with acryloyl chloride under second reactive conditions in a second solution to form a silyl protected diacrylamide compound.Type: GrantFiled: February 8, 2013Date of Patent: June 23, 2015Assignee: Life Technologies CorporationInventors: Nini Kjus, Geir Fonnum, Bruce Branchaud, Lai-Qiang Ying, Steven Menchen, Dmitriy Gremyachinskiy, Hee Chol Kang
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Publication number: 20120141798Abstract: This invention relates to monodisperse cross-linked polymer particles, comprising particles with a substantially smooth outer surface and an average diameter of less than 1 ?m, wherein the particles are solid or porous, and wherein the coefficient of variation (CV) % of the particles, when measured by CPS disk centrifugation analysis, is less than 15%. These monodisperse cross-linked polymer particles may comprise magnetic material and are useful in various application. This invention also relates to monodisperse polymer particles for use as seed particles in the Ugelstad process.Type: ApplicationFiled: April 29, 2010Publication date: June 7, 2012Applicant: INVITROGEN DYNAL ASInventors: Grete Irene Modahl, Geir Fonnum, Astrid Molteberg, Silje Lien, Nini Kjus
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Patent number: 8038987Abstract: A process for the preparation of coated polymer particles containing superparamagnetic crystals, said process comprising reacting porous, surface-functionalized, superparamagnetic crystal-containing polymer particles of diameter 0.5 to 1.8 ?m with at least one polyisocyanate and at least one diol or at least one epoxide.Type: GrantFiled: November 27, 2006Date of Patent: October 18, 2011Assignee: Invitrogen Dynal ASInventors: Geir Fonnum, Nini Kjus Hofsløkken, Elin Marie Aksnes, Lars Kilaas, Arvid Trygve Berge, Per Stenstad, Ruth Schmid, Jon Olav Bjorgum, Tom-Nils Nilsen
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Patent number: 7160707Abstract: A process for the preparation of coated polymer particles containing superparamagnetic crystals, said process comprising reacting porous, surface-functionalized, superparamagnetic crystal-containing polymer particles of diameter 0.5 to 1.8 ?m with at least one polyisocyanate and at least one diol or at least one epoxide.Type: GrantFiled: March 3, 2005Date of Patent: January 9, 2007Assignee: Dynal Biotech ASAInventors: Geir Fonnum, Nini Kjus Hofsløkken, Elin Marie Aksnes, Lars Kilaas, Arvid Trygve Berge, Ruth Schmid, Jon Olav Bjorgum
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Publication number: 20060189797Abstract: A conjugate comprising a magnetic polymer particle bound to a carboxymethylated aspartate chelating ligand, optionally chelating a metal ion.Type: ApplicationFiled: June 28, 2004Publication date: August 24, 2006Inventors: Pal Songe, Geir Fonnum, Nini Kjus, Marcel Sandeerg, Solveig Nordstrand, Inger Aukrust
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Patent number: 6986913Abstract: A process for the preparation of coated polymer particles containing superparamagnetic crystals, said process comprising reacting porous, surface-functionalized, superparamagnetic crystal-containing polymer particles of diameter 0.5 to 1.8 ?m with at least one polyisocyanate and at least one diol or at least one epoxide.Type: GrantFiled: April 28, 2004Date of Patent: January 17, 2006Assignee: Dynal Biotech ASAInventors: Geir Fonnum, Nini Kjus Hofsløkken, Elin Marie Aksnes, Lars Kilaas, Arvid Trygve Berge, Per Stenstad, Ruth Schmid, Jon Olav Bjorgum, Tom-Nils Nilsen
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Publication number: 20050147822Abstract: A process for the preparation of coated polymer particles containing superparamagnetic crystals, said process comprising reacting porous, surface-functionalized, superparamagnetic crystal-containing polymer particles of diameter 0.5 to 1.8 ?m with at least one polyisocyanate and at least one diol or at least one epoxide.Type: ApplicationFiled: March 3, 2005Publication date: July 7, 2005Inventors: Geir Fonnum, Nini Kjus, Elin Aksnes, Lars Kilaas, Arvid Berge, Per Stenstad, Ruth Schmid, Jon Bjorgum, Tom-Nils Nilsen
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Publication number: 20050014001Abstract: A process for the preparation of coated polymer particles containing superparamagnetic crystals, said process comprising reacting porous, surface-functionalized, superparamagnetic crystal-containing polymer particles of diameter 0.5 to 1.8 ?m with at least one polyisocyanate and at least one diol or at least one epoxide.Type: ApplicationFiled: April 28, 2004Publication date: January 20, 2005Inventors: Geir Fonnum, Nini Kjus, Elin Aksnes, Lars Kilaas, Arvid Berge, Per Stenstad, Ruth Schmid, Jon Bjorgum, Tom-Nils Nilsen