Patents by Inventor Nir Altschuler

Nir Altschuler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190070333
    Abstract: This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.
    Type: Application
    Filed: August 21, 2018
    Publication date: March 7, 2019
    Applicant: CARTIHEAL (2009) LTD.
    Inventors: Nir Altschuler, Razi Vago
  • Publication number: 20190053815
    Abstract: This invention provides tools and kits for removal of a graft and/or for implantation of a solid or semi-solid form or graft within an appropriate desired tissue minimizing the potential for or actual breakage of the implant or graft during the stated process. Kits comprising such tools and methods making use of same are provided, as well.
    Type: Application
    Filed: August 20, 2018
    Publication date: February 21, 2019
    Applicant: Cartiheal (2009) Ltd.
    Inventors: Nir Altschuler, Amir Goren
  • Publication number: 20180339081
    Abstract: This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.
    Type: Application
    Filed: July 30, 2018
    Publication date: November 29, 2018
    Applicant: CARTIHEAL (2009) LTD.
    Inventors: Nir Altschuler, Razi Vago
  • Patent number: 10080818
    Abstract: This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: September 25, 2018
    Assignee: Cartiheal (2009) Ltd.
    Inventors: Nir Altschuler, Razi Vago
  • Patent number: 10046084
    Abstract: This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.
    Type: Grant
    Filed: March 1, 2016
    Date of Patent: August 14, 2018
    Assignee: CARTIHEAL (2009) LTD.
    Inventors: Nir Altschuler, Razi Vago
  • Publication number: 20180154041
    Abstract: This invention provides optimized solid substrates for promoting cell or tissue growth or restored function, which solid substrate comprises aragonite and is characterized by a specific fluid uptake capacity value of at least 75%, or a contact angle value of less than 60 degrees when in contact with a fluid and which is further characterized by tapered sides and tools for implantation of optimized solid substrates.
    Type: Application
    Filed: May 4, 2016
    Publication date: June 7, 2018
    Applicant: CARTIHEAL (2009) LTD
    Inventors: Nir ALTSCHULER, Amir GOREN
  • Patent number: 9770531
    Abstract: This invention provides solid substrates for mitigating or preventing cell or tissue adherence and/or vascularization, which solid substrates comprise a marine organism skeletal derivative and are characterized by a specific fluid uptake capacity value of less than 40%, processes for selection of the same and applications of the same. This invention also provides solid substrates for mitigating or preventing cell or tissue adherence and/or vascularization, which solid substrates are characterized by having a contact angle value of more than 60 degrees, when in contact with a fluid. This invention also provides solid substrates for mitigating or preventing cell or tissue adherence and/or vascularization, which solid substrate is characterized by a minimal surface roughness (Ra) or substantial surface smoothness, as measured by scanning electron microscopy or atomic force microscopy. The invention also provides processes for selection of an optimized coral-based solid substrate.
    Type: Grant
    Filed: February 10, 2014
    Date of Patent: September 26, 2017
    Assignee: CARTIHEAL (2009) LTD
    Inventor: Nir Altschuler
  • Publication number: 20160184477
    Abstract: This invention provides solid substrates for promoting cell or tissue growth or restored function, which solid substrate is characterized by a specific fluid uptake capacity value of at least 75%, which specific fluid uptake capacity value is determined by establishing a spontaneous fluid uptake value divided by a total fluid uptake value. This invention also provides solid substrate for promoting cell or tissue growth or restored function, which solid substrate is characterized by having a contact angle value of less than 60 degrees, when in contact with a fluid. This inventions also provides solid substrates for promoting cell or tissue growth or restored function, which solid substrate is characterized by a substantial surface roughness (Ra) as measured by scanning electron microscopy or atomic force microscopy. The invention also provides for processes for selection of an optimized coral-based solid substrate for promoting cell or tissue growth or restored function and application of the same.
    Type: Application
    Filed: December 30, 2015
    Publication date: June 30, 2016
    Applicant: CARTHEAL (2009) LTD.
    Inventor: Nir ALTSCHULER
  • Publication number: 20160175098
    Abstract: This invention provides coral-based scaffolds for cartilage repair, and instruments for insertion and utilization of same within a site of cartilage repair.
    Type: Application
    Filed: December 22, 2015
    Publication date: June 23, 2016
    Applicant: CARTIHEAL (2009) LTD.
    Inventors: Nir ALTSCHULER, Razi VAGO
  • Publication number: 20160175480
    Abstract: This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.
    Type: Application
    Filed: March 1, 2016
    Publication date: June 23, 2016
    Applicant: CARTIHEAL (2009) LTD.
    Inventors: Nir ALTSCHULER, Razi Vago
  • Publication number: 20160000969
    Abstract: This invention provides solid substrates for promoting cell or tissue growth or restored function, which solid substrate is characterized by a specific fluid uptake capacity value of at least 75%, which specific fluid uptake capacity value is determined by establishing a spontaneous fluid uptake value divided by a total fluid uptake value. This invention also provides solid substrates for promoting cell or tissue growth or restored function, which solid substrate is characterized by having a contact angle value of less than 60 degrees, when in contact with a fluid. This invention also provides solid substrates for promoting cell or tissue growth or restored function, which solid substrate is characterized by a substantial surface roughness (Ra) as measured by scanning electron microscopy or atomic force microscopy. The invention also provides for processes for selection of an optimized coral-based solid substrate for promoting cell or tissue growth or restored function and applications of the same.
    Type: Application
    Filed: February 10, 2014
    Publication date: January 7, 2016
    Applicant: CARTIHEAL (2009) LTD
    Inventor: Nir ALTSCHULER
  • Publication number: 20150374880
    Abstract: This invention provides solid substrates for mitigating or preventing cell or tissue adherence and/or vascularization, which solid substrate comprises a marine organism skeletal derivative and is characterized by a specific fluid uptake capacity value of less than 40%, which specific fluid uptake capacity value is determined by establishing a spontaneous fluid uptake value divided by a total fluid uptake value and processes for selection of an optimized marine organism skeletal derivative-based solid substrate for mitigating or preventing cell or tissue adherence and/or vascularization and applications of the same. This invention also provides solid substrates for mitigating or preventing cell or tissue adherence and/or vascularization, which solid substrate is characterized by having a contact angle value of more than 60 degrees, when in contact with a fluid.
    Type: Application
    Filed: February 10, 2014
    Publication date: December 31, 2015
    Applicant: CARTIHEAL (2009) LTD
    Inventor: Nir ALTSCHULER
  • Publication number: 20150289889
    Abstract: This invention provides tools and kits for removal of a graft and/or for implantation of a solid or semi-solid form or graft within an appropriate desired tissue minimizing the potential for or actual breakage of the implant or graft during the stated process. Kits comprising such tools and methods making use of same are provided, as well.
    Type: Application
    Filed: November 11, 2013
    Publication date: October 15, 2015
    Applicant: CARTIHEAL (2009) LTD.
    Inventors: Nir Altschuler, Amir Goren
  • Publication number: 20150147397
    Abstract: This invention is directed to aragonite and calcite hydrogel biomatrices, optionally seeded with precursor cells and uses thereof in tissue engineering, regeneration and repair, including in inducing or enhancing bone formation, cartilage formation or a combination thereof in a subject, and kits related thereto.
    Type: Application
    Filed: April 29, 2013
    Publication date: May 28, 2015
    Inventor: Nir Altschuler
  • Publication number: 20150134065
    Abstract: This invention provides aragonite- and calcite-based solid substrates for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which solid substrates comprise or are made to ultimately comprise three phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, and methods of use thereof.
    Type: Application
    Filed: April 4, 2013
    Publication date: May 14, 2015
    Inventor: Nir Altschuler
  • Publication number: 20150056262
    Abstract: This invention provides coral-based scaffolds for cartilage repair, and instruments for insertion and utilization of same within a site of cartilage repair.
    Type: Application
    Filed: July 1, 2014
    Publication date: February 26, 2015
    Inventors: Nir Altschuler, Razi Vago
  • Publication number: 20140287017
    Abstract: This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.
    Type: Application
    Filed: June 11, 2014
    Publication date: September 25, 2014
    Applicant: CARTIHEAL (2009) LTD.
    Inventors: Nir ALTSCHULER, Razi VAGO
  • Patent number: 8808725
    Abstract: This invention provides coral-based scaffolds for cartilage repair, and instruments for insertion and utilization of same within a site of cartilage repair.
    Type: Grant
    Filed: November 19, 2009
    Date of Patent: August 19, 2014
    Assignee: Cartiheal (2009) Ltd.
    Inventors: Nir Altschuler, Razi Vago
  • Patent number: 8802115
    Abstract: This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.
    Type: Grant
    Filed: May 23, 2010
    Date of Patent: August 12, 2014
    Assignee: Cartiheal (2009) Ltd.
    Inventors: Nir Altschuler, Razi Vago
  • Patent number: 8790681
    Abstract: This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.
    Type: Grant
    Filed: May 23, 2010
    Date of Patent: July 29, 2014
    Assignee: Cartiheal (2009) Ltd.
    Inventors: Nir Altschuler, Razi Vago