Patents by Inventor Nir Altschuler
Nir Altschuler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190070333Abstract: This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.Type: ApplicationFiled: August 21, 2018Publication date: March 7, 2019Applicant: CARTIHEAL (2009) LTD.Inventors: Nir Altschuler, Razi Vago
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Publication number: 20190053815Abstract: This invention provides tools and kits for removal of a graft and/or for implantation of a solid or semi-solid form or graft within an appropriate desired tissue minimizing the potential for or actual breakage of the implant or graft during the stated process. Kits comprising such tools and methods making use of same are provided, as well.Type: ApplicationFiled: August 20, 2018Publication date: February 21, 2019Applicant: Cartiheal (2009) Ltd.Inventors: Nir Altschuler, Amir Goren
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Publication number: 20180339081Abstract: This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.Type: ApplicationFiled: July 30, 2018Publication date: November 29, 2018Applicant: CARTIHEAL (2009) LTD.Inventors: Nir Altschuler, Razi Vago
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Patent number: 10080818Abstract: This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.Type: GrantFiled: June 11, 2014Date of Patent: September 25, 2018Assignee: Cartiheal (2009) Ltd.Inventors: Nir Altschuler, Razi Vago
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Patent number: 10046084Abstract: This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.Type: GrantFiled: March 1, 2016Date of Patent: August 14, 2018Assignee: CARTIHEAL (2009) LTD.Inventors: Nir Altschuler, Razi Vago
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Publication number: 20180154041Abstract: This invention provides optimized solid substrates for promoting cell or tissue growth or restored function, which solid substrate comprises aragonite and is characterized by a specific fluid uptake capacity value of at least 75%, or a contact angle value of less than 60 degrees when in contact with a fluid and which is further characterized by tapered sides and tools for implantation of optimized solid substrates.Type: ApplicationFiled: May 4, 2016Publication date: June 7, 2018Applicant: CARTIHEAL (2009) LTDInventors: Nir ALTSCHULER, Amir GOREN
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Patent number: 9770531Abstract: This invention provides solid substrates for mitigating or preventing cell or tissue adherence and/or vascularization, which solid substrates comprise a marine organism skeletal derivative and are characterized by a specific fluid uptake capacity value of less than 40%, processes for selection of the same and applications of the same. This invention also provides solid substrates for mitigating or preventing cell or tissue adherence and/or vascularization, which solid substrates are characterized by having a contact angle value of more than 60 degrees, when in contact with a fluid. This invention also provides solid substrates for mitigating or preventing cell or tissue adherence and/or vascularization, which solid substrate is characterized by a minimal surface roughness (Ra) or substantial surface smoothness, as measured by scanning electron microscopy or atomic force microscopy. The invention also provides processes for selection of an optimized coral-based solid substrate.Type: GrantFiled: February 10, 2014Date of Patent: September 26, 2017Assignee: CARTIHEAL (2009) LTDInventor: Nir Altschuler
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Publication number: 20160184477Abstract: This invention provides solid substrates for promoting cell or tissue growth or restored function, which solid substrate is characterized by a specific fluid uptake capacity value of at least 75%, which specific fluid uptake capacity value is determined by establishing a spontaneous fluid uptake value divided by a total fluid uptake value. This invention also provides solid substrate for promoting cell or tissue growth or restored function, which solid substrate is characterized by having a contact angle value of less than 60 degrees, when in contact with a fluid. This inventions also provides solid substrates for promoting cell or tissue growth or restored function, which solid substrate is characterized by a substantial surface roughness (Ra) as measured by scanning electron microscopy or atomic force microscopy. The invention also provides for processes for selection of an optimized coral-based solid substrate for promoting cell or tissue growth or restored function and application of the same.Type: ApplicationFiled: December 30, 2015Publication date: June 30, 2016Applicant: CARTHEAL (2009) LTD.Inventor: Nir ALTSCHULER
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Publication number: 20160175098Abstract: This invention provides coral-based scaffolds for cartilage repair, and instruments for insertion and utilization of same within a site of cartilage repair.Type: ApplicationFiled: December 22, 2015Publication date: June 23, 2016Applicant: CARTIHEAL (2009) LTD.Inventors: Nir ALTSCHULER, Razi VAGO
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Publication number: 20160175480Abstract: This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.Type: ApplicationFiled: March 1, 2016Publication date: June 23, 2016Applicant: CARTIHEAL (2009) LTD.Inventors: Nir ALTSCHULER, Razi Vago
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Publication number: 20160000969Abstract: This invention provides solid substrates for promoting cell or tissue growth or restored function, which solid substrate is characterized by a specific fluid uptake capacity value of at least 75%, which specific fluid uptake capacity value is determined by establishing a spontaneous fluid uptake value divided by a total fluid uptake value. This invention also provides solid substrates for promoting cell or tissue growth or restored function, which solid substrate is characterized by having a contact angle value of less than 60 degrees, when in contact with a fluid. This invention also provides solid substrates for promoting cell or tissue growth or restored function, which solid substrate is characterized by a substantial surface roughness (Ra) as measured by scanning electron microscopy or atomic force microscopy. The invention also provides for processes for selection of an optimized coral-based solid substrate for promoting cell or tissue growth or restored function and applications of the same.Type: ApplicationFiled: February 10, 2014Publication date: January 7, 2016Applicant: CARTIHEAL (2009) LTDInventor: Nir ALTSCHULER
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Publication number: 20150374880Abstract: This invention provides solid substrates for mitigating or preventing cell or tissue adherence and/or vascularization, which solid substrate comprises a marine organism skeletal derivative and is characterized by a specific fluid uptake capacity value of less than 40%, which specific fluid uptake capacity value is determined by establishing a spontaneous fluid uptake value divided by a total fluid uptake value and processes for selection of an optimized marine organism skeletal derivative-based solid substrate for mitigating or preventing cell or tissue adherence and/or vascularization and applications of the same. This invention also provides solid substrates for mitigating or preventing cell or tissue adherence and/or vascularization, which solid substrate is characterized by having a contact angle value of more than 60 degrees, when in contact with a fluid.Type: ApplicationFiled: February 10, 2014Publication date: December 31, 2015Applicant: CARTIHEAL (2009) LTDInventor: Nir ALTSCHULER
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Publication number: 20150289889Abstract: This invention provides tools and kits for removal of a graft and/or for implantation of a solid or semi-solid form or graft within an appropriate desired tissue minimizing the potential for or actual breakage of the implant or graft during the stated process. Kits comprising such tools and methods making use of same are provided, as well.Type: ApplicationFiled: November 11, 2013Publication date: October 15, 2015Applicant: CARTIHEAL (2009) LTD.Inventors: Nir Altschuler, Amir Goren
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Publication number: 20150147397Abstract: This invention is directed to aragonite and calcite hydrogel biomatrices, optionally seeded with precursor cells and uses thereof in tissue engineering, regeneration and repair, including in inducing or enhancing bone formation, cartilage formation or a combination thereof in a subject, and kits related thereto.Type: ApplicationFiled: April 29, 2013Publication date: May 28, 2015Inventor: Nir Altschuler
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Publication number: 20150134065Abstract: This invention provides aragonite- and calcite-based solid substrates for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which solid substrates comprise or are made to ultimately comprise three phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, and methods of use thereof.Type: ApplicationFiled: April 4, 2013Publication date: May 14, 2015Inventor: Nir Altschuler
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Publication number: 20150056262Abstract: This invention provides coral-based scaffolds for cartilage repair, and instruments for insertion and utilization of same within a site of cartilage repair.Type: ApplicationFiled: July 1, 2014Publication date: February 26, 2015Inventors: Nir Altschuler, Razi Vago
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Publication number: 20140287017Abstract: This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.Type: ApplicationFiled: June 11, 2014Publication date: September 25, 2014Applicant: CARTIHEAL (2009) LTD.Inventors: Nir ALTSCHULER, Razi VAGO
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Patent number: 8808725Abstract: This invention provides coral-based scaffolds for cartilage repair, and instruments for insertion and utilization of same within a site of cartilage repair.Type: GrantFiled: November 19, 2009Date of Patent: August 19, 2014Assignee: Cartiheal (2009) Ltd.Inventors: Nir Altschuler, Razi Vago
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Patent number: 8802115Abstract: This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.Type: GrantFiled: May 23, 2010Date of Patent: August 12, 2014Assignee: Cartiheal (2009) Ltd.Inventors: Nir Altschuler, Razi Vago
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Patent number: 8790681Abstract: This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.Type: GrantFiled: May 23, 2010Date of Patent: July 29, 2014Assignee: Cartiheal (2009) Ltd.Inventors: Nir Altschuler, Razi Vago