Patents by Inventor Nir Barzilai

Nir Barzilai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8703496
    Abstract: This invention provides methods of using of the sizes and levels of high-density lipoprotein (HDL) and low-density lipoprotein (LDL) particles, the ?641 allele of the promoter of the gene encoding apolipoprotein C-3 (APOC-3), the 405 allele of the gene encoding cholesteryl ester transfer protein (CETP), and plasma levels of insulin-like growth factor-1 (IGF-1), adiponectin, CETP and APOC-3, for determining and increasing an individual's likelihood of longevity and of retaining cognitive function during aging, and for determining and decreasing an individual's likelihood of developing a cardiovascular-, metabolic- or age-related disease.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: April 22, 2014
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Nir Barzilai, Richard B. Lipton
  • Publication number: 20130244333
    Abstract: This invention provides methods of using of the sizes and levels of high-density lipoprotein (HDL) and low-density lipoprotein (LDL) particles, the ?641 allele of the promoter of the gene encoding apolipoprotein C-3 (APOC-3), the 405 allele of the gene encoding cholesteryl ester transfer protein (CETP), and plasma levels of insulin-like growth factor-1 (IGF-1), adiponectin, CETP and APOC-3, for determining and increasing an individual's likelihood of longevity and of retaining cognitive function during aging, and for determining and decreasing an individual's likelihood of developing a cardiovascular-, metabolic- or age-related disease.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 19, 2013
    Applicant: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Nir Barzilai, Richard B. Lipton
  • Patent number: 8399258
    Abstract: This invention provides methods of using of the sizes and levels of high-density lipoprotein (HDL) and low-density lipoprotein (LDL) particles, the ?641 allele of the promoter of the gene encoding apolipoprotein C-3 (APOC-3), the 405 allele of the gene encoding cholesteryl ester transfer protein (CETP), and plasma levels of insulin-like growth factor-1 (IGF-1), adiponectin, CETP and APOC-3, for determining and increasing an individual's likelihood of longevity and of retaining cognitive function during aging, and for determining and decreasing an individual's likelihood of developing a cardiovascular-, metabolic- or age-related disease.
    Type: Grant
    Filed: December 5, 2008
    Date of Patent: March 19, 2013
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventor: Nir Barzilai
  • Publication number: 20130045916
    Abstract: Provided are methods of using humanin and humanin analogs to treat a mammal exhibiting or at risk for insulin resistance, increase insulin sensitivity in a mammal exhibiting or at risk for insulin resistance, treat type-2 diabetes mellitus, metabolic syndrome, and neurodegeneration, treat and prevent myocardial injury, and determine longevity.
    Type: Application
    Filed: October 9, 2012
    Publication date: February 21, 2013
    Applicants: The Regeants of the University of California, Albert Einstein College of Medicine of Yeshiva University
    Inventors: Nir Barzilai, Pinchas Cohen, Radhika Muzumdar, David Lefer
  • Patent number: 8309525
    Abstract: Provided are methods of using humanin and humanin analogs to treat a mammal exhibiting or at risk for insulin resistance, increase insulin sensitivity in a mammal exhibiting or at risk for insulin resistance, treat type-2 diabetes mellitus, metabolic syndrome, and neurodegeneration, treat and prevent myocardial injury, and determine longevity.
    Type: Grant
    Filed: May 28, 2008
    Date of Patent: November 13, 2012
    Assignees: Albert Einstein College of Medicine of Yeshiva University, The Regents of the University of California
    Inventors: Nir Barzilai, Pinchas Cohen, Radhika Muzumdar
  • Publication number: 20110189668
    Abstract: The present invention provides a method for identifying a subject's likelihood of achieving longevity or of developing an age-related disease, the method for identifying a subject's likelihood of achieving longevity or of developing an age-related disease comprising detecting at least one specified single nucleotide polymorphisms or genotype at a single nucleotide polymorphism or combination of a genotype at a first single nucleotide polymorphism and a genotype at a second single nucleotide polymorphism in a sample of the subject's DNA and, wherein the detection of at least one single nucleotide polymorphisms or genotype at a single nucleotide polymorphism or combination of a genotype at a first single nucleotide polymorphism and a genotype at a second single nucleotide polymorphism identifies the subject's as likely achieving longevity or of developing an age-related disease.
    Type: Application
    Filed: January 21, 2011
    Publication date: August 4, 2011
    Inventors: Aviv Bergman, Nir Barzilai, Gil Atzmon
  • Publication number: 20100204099
    Abstract: Provided are methods of using humanin and humanin analogs to treat a mammal exhibiting or at risk for insulin resistance, increase insulin sensitivity in a mammal exhibiting or at risk for insulin resistance, treat type-2 diabetes mellitus, metabolic syndrome, and neurodegeneration, treat and prevent myocardial injury, and determine longevity.
    Type: Application
    Filed: May 28, 2008
    Publication date: August 12, 2010
    Inventors: Nir Barzilai, Pinchas Cohen, Radhika Muzumdar, David Lefer
  • Publication number: 20090155915
    Abstract: This invention provides methods of using of the sizes and levels of high-density lipoprotein (HDL) and low-density lipoprotein (LDL) particles, the -641 allele of the promoter of the gene encoding apolipoprotein C-3 (APOC-3), the 405 allele of the gene encoding cholesteryl ester transfer protein (CETP), and plasma levels of insulin-like growth factor-1 (IGF-1), adiponectin, CETP and APOC-3, for determining and increasing an individual's likelihood of longevity and of retaining cognitive function during aging, and for determining and decreasing an individual's likelihood of developing a cardiovascular-, metabolic- or age-related disease.
    Type: Application
    Filed: December 5, 2008
    Publication date: June 18, 2009
    Inventor: Nir Barzilai
  • Patent number: 7491543
    Abstract: This invention provides methods of using of the sizes and levels of high-density lipoprotein (HDL) and low-density lipoprotein (LDL) particles, the -641 allele of the promoter of the gene encoding apolipoprotein C-3 (APOC-3), the 405 allele of the gene encoding cholesteryl ester transfer protein (CETP), and plasma levels of insulin-like growth factor-1 (IGF-1), adiponectin, CETP and APOC-3, for determining and increasing an individual's likelihood of longevity and of retaining cognitive function during aging, and for determining and decreasing an individual's likelihood of developing a cardiovascular-, metabolic- or age-related disease.
    Type: Grant
    Filed: September 16, 2005
    Date of Patent: February 17, 2009
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventor: Nir Barzilai
  • Publication number: 20060068432
    Abstract: This invention provides methods of using of the sizes and levels of high-density lipoprotein (HDL) and low-density lipoprotein (LDL) particles, the ?641 allele of the promoter of the gene encoding apolipoprotein C-3 (APOC-3), the 405 allele of the gene encoding cholesteryl ester transfer protein (CETP), and plasma levels of insulin-like growth factor-1 (IGF-1), adiponectin, CETP and APOC-3, for determining and increasing an individual's likelihood of longevity and of retaining cognitive function during aging, and for determining and decreasing an individual's likelihood of developing a cardiovascular-, metabolic- or age-related disease.
    Type: Application
    Filed: September 16, 2005
    Publication date: March 30, 2006
    Inventor: Nir Barzilai