Abstract: A closure device (320) is provided for suturing a puncture. The closure device (320) includes a suture (322, 822), an elongate support (328), a suture-positioning support (330), and an elongate dilator (344). The suture-positioning support (330) is coupled to a distal end portion (332) of the elongate support (328), laterally extendable with respect to the distal end portion (332) of the elongate support (328), and configured to removably receive the suture (322, 822). The dilator (344) is configured to be inserted through the puncture, and has a proximal end (348) that is coupled to the distal end portion (332) of the elongate support (328). The closure device (320) is configured to allow movement of the distal end portion (332) of the elongate support (328) with respect to the proximal end (348) of the dilator (344) with at least two degrees of freedom. Other embodiments are also described.

Abstract: A naso/orogastric device having backflow blocking means and comprises a naso/orogastric tube sized and shaped for being disposed within the esophagus so that at least a distal end thereof being placed in the stomach lumen of a patient, at least one elastic esophageal body, positioned along the naso/orogastric tube, having a pressure dependent volume, at least one esophageal sensor that detects fluid around at least one segment of the naso/orogastric tube, and a pressure regulator that regulates a pressure within the elastic esophageal body according to the detection.

Abstract: A naso/orogastric device having backflow blocking means and comprises a naso/orogastric tube sized and shaped for being disposed within the esophagus so that at least a distal end thereof being placed in the stomach lumen of a patient, at least one elastic esophageal body, positioned along the naso/orogastric tube, having a pressure dependent volume, at least one esophageal sensor that detects fluid around at least one segment of the naso/orogastric tube, and a pressure regulator that regulates a pressure within the elastic esophageal body according to the detection.

Abstract: An improved device delivers a fluid medicament to the subcutaneous tissue of a user. The device is better suited for patients with Parkinson's Disease and other central nervous system disorders, than conventional infusion devices. The device can include a reusable part including a drive component (e.g., motor) and control electronics and a disposable part including a medicament reservoir. Medicament can be evacuated from the medicament reservoir by a plunger assembly that includes a plunger attached to a lead screw that is rotated by a nut, all within the disposable part. The device can be fluidically coupled with the tissue via a flexible cannula. Various embodiments relate to an improved cannula insertion mechanism that delivers the cannula under a force applied by a spring. Various embodiments relate to improved filling of the device, for example, using a vial adapter and an automated filling station.

Abstract: A medical pump, comprising: a fluid housing having a plurality of intake openings, sealed by at least one intake valve, and an outlet opening sealed by an outlet valve; a piston which is sealing the fluid housing and connected to a drive mechanism, the drive mechanism pulls the piston to draw fluid from one of the plurality of intake openings and pushes the piston to discharge the fluid into the outlet opening; and a selecting valve enclosing at least two tubes, each providing fluid to one of the plurality of intake openings, wherein the selecting valve closes one of the at least two tubes while opening another of the at least two tubes.

Abstract: There is provided a system for mixed imaging modalities including impedance based analysis of a body portion of a patient, comprising: multi conductor busbar(s), each connected to a controller and at least two of multiple sensing components, a controller arranged to: iteratively perform: sequentially activate as a current source, a first sensing component previously un-used as the current source in earlier iterations, sequentially activating as a current sink, a second sensing component previously un-used as the current sink in earlier iterations, obtain surface voltages, by sequentially activating each of the other sensing components as a respective voltage sensor, and obtaining a respective voltage reading while alternating current is transmitted between the first and second sensing components, wherein the voltages and current obtained for each pair of first and second sensing component of each iteration are provided for computation of a 3D dataset of 3D impedance values of the body portion.

Abstract: An improved device delivers a fluid medicament to the subcutaneous tissue of a user. The device is better suited for patients with Parkinson's Disease and other central nervous system disorders, than conventional infusion devices. The device can include a reusable part including a drive component (e.g., motor) and control electronics and a disposable part including a medicament reservoir. Medicament can be evacuated from the medicament reservoir by a plunger assembly that includes a plunger attached to a lead screw that is rotated by a nut, all within the disposable part. The device can be fluidically coupled with the tissue via a flexible cannula. Various embodiments relate to an improved cannula insertion mechanism that delivers the cannula under a force applied by a spring. Various embodiments relate to improved filling of the device, for example, using a vial adapter and an automated filling station.

Abstract: The present invention relates to bone-implants for treating a lesion on a bone, comprising: a bone anchor, a container in communication with the bone anchor and an osteoconductive bone-filler material inside the container, and methods thereof.

Abstract: A medical pump, comprising: a fluid housing having a plurality of intake openings, sealed by at least one intake valve, and an outlet opening sealed by an outlet valve; a piston which is sealing the fluid housing and connected to a drive mechanism, the drive mechanism pulls the piston to draw fluid from one of the plurality of intake openings and pushes the piston to discharge the fluid into the outlet opening; and a selecting valve enclosing at least two tubes, each providing fluid to one of the plurality of intake openings, wherein the selecting valve closes one of the at least two tubes while opening another of the at least two tubes.

Abstract: An improved device delivers a fluid medicament to the subcutaneous tissue of a user. The device is better suited for patients with Parkinson's Disease and other central nervous system disorders, than conventional infusion devices. The device can include a reusable part including a drive component (e.g., motor) and control electronics and a disposable part including a medicament reservoir. Medicament can be evacuated from the medicament reservoir by a plunger assembly that includes a plunger attached to a lead screw that is rotated by a nut, all within the disposable part. The device can be fluidically coupled with the tissue via a flexible cannula. Various embodiments relate to an improved cannula insertion mechanism that delivers the cannula under a force applied by a spring. Various embodiments relate to improved filling of the device, for example, using a vial adapter and an automated filling station.

Abstract: Apparatus and methods for occluding hollow body structures, such as blood vessels, and for attaching tissue layers together by providing implantable elements on opposite sides of the structure or tissue layers and drawing the implants together to occlude the body structure and/or bring the tissue layers together. The implants are deliverable in a low-profile configuration and self-expand to an enlarged configuration. The implantable elements are delivered by transfixing the body structure, then releasing the implants on opposite sides of the body structure and drawing the implants together to effect an occlusion or attachment. The implants are configured to apply oppositely directed forces to opposite surfaces of the tissue layers at alternate, circumferentially spaced locations and may constrain the tissue in a serpentine pattern or in a direct clamping pattern. The implants grip the tissue in a manner that defines a pressure zone about the transfixion aperture that prevents leakage from the aperture.

Abstract: The present invention relates to bone-implants for treating a lesion on a bone, comprising: a bone anchor, a container in communication with the bone anchor and an osteoconductive bone-filler material inside the container, and methods thereof.

Abstract: An improved device delivers a fluid medicament to the subcutaneous tissue of a user. The device is better suited for patients with Parkinson's Disease and other central nervous system disorders, than conventional infusion devices. The device can include a reusable part including a drive component (e.g., motor) and control electronics and a disposable part including a medicament reservoir. Medicament can be evacuated from the medicament reservoir by a plunger assembly that includes a plunger attached to a lead screw that is rotated by a nut, all within the disposable part. The device can be fluidically coupled with the tissue via a flexible cannula. Various embodiments relate to an improved cannula insertion mechanism that delivers the cannula under a force applied by a spring. Various embodiments relate to improved filling of the device, for example, using a vial adapter and an automated filling station.

Abstract: Method and apparatus for delivering multiple tissue fasteners with needle and fastener assemblies each of which comprises a hollow needle adapted to be passed through tissue layers to be fastened, the needle containing a proximal and a distal implant, the implants being configured to self-expand when ejected from the needle, the implants being lockable to each other after ejection in response to drawing the implants together with tissue gripped between the implants.

Abstract: The present invention relates to bone-implants for treating a lesion on a bone, comprising: a bone anchor, a container in communication with the bone anchor and an osteoconductive bone-filler material inside the container, and methods thereof.

Abstract: There is provided a system for mixed imaging modalities including impedance based analysis of a body portion of a patient, comprising: multi conductor busbar(s), each connected to a controller and at least two of multiple sensing components, a controller arranged to: iteratively perform: sequentially activate as a current source, a first sensing component previously un-used as the current source in earlier iterations, sequentially activating as a current sink, a second sensing component previously un-used as the current sink in earlier iterations, obtain surface voltages, by sequentially activating each of the other sensing components as a respective voltage sensor, and obtaining a respective voltage reading while alternating current is transmitted between the first and second sensing components, wherein the voltages and current obtained for each pair of first and second sensing component of each iteration are provided for computation of a 3D dataset of 3D impedance values of the body portion.

Abstract: Apparatus and methods are provided for occluding blood vessels and other anatomical structures. Occlusion devices are delivered percutaneously and extraluminally through a small gauge needle and include expandable elements that are deployable on opposite sides of a target vessel to be occluded. When positioned about the vessel the elements are expanded and brought together to compress and occlude the vessel. Embodiments include those adapted for temporary as well as permanent use.

Abstract: The present invention relates to bone-implants for treating a lesion on a bone, comprising: a bone anchor, a container in communication with said anchor and an osteoconductive bone-filler material inside said container, and methods thereof.

Abstract: There is provided a system for mixed imaging modalities including impedance based analysis of a body portion of a patient, comprising: multi conductor busbar(s), each connected to a controller and at least two of multiple sensing components, a controller arranged to: iteratively perform: sequentially activate as a current source, a first sensing component previously un-used as the current source in earlier iterations, sequentially activating as a current sink, a second sensing component previously un-used as the current sink in earlier iterations, obtain surface voltages, by sequentially activating each of the other sensing components as a respective voltage sensor, and obtaining a respective voltage reading while alternating current is transmitted between the first and second sensing components, wherein the voltages and current obtained for each pair of first and second sensing component of each iteration are provided for computation of a 3D dataset of 3D impedance values of the body portion.