Patents by Inventor Niraj H. Tolia

Niraj H. Tolia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHETIC PLASMODIUM ANTIGENS, COMPOSITIONS, AND USES THEREOF
    Publication number: 20240083956
    Abstract: Provided herein are synthetic P. vivax antigens, antibodies and pharmaceutical formulations and vaccines thereof. Also provided herein are methods of treating and/or preventing Plasmodium infection and/or disease by administering the synthetic P. vivax antigens, antibodies and pharmaceutical formulations and vaccines thereof.
    Type: Application
    Filed: September 19, 2023
    Publication date: March 14, 2024
    Inventors: John H. Adams, Christopher L. King, Niraj H. Tolia, Edwin Chen, Nichole Diane Salinas, Miriam Thankam George, Francis B. Ntumngia, Samantha Jones Barnes
  • NOVEL VAR2CSA IMMUNOGENS AND METHODS OF USE THEREOF
    Publication number: 20240009290
    Abstract: The disclosure provides immunogen polypeptides comprising fragments of VAR2CSA protein expressed by P. falciparum. Aspects of the disclosed immunogen polypeptides comprise all or portions of the CSA binding regions of VAR2CSA as identified by a structural study of VAR2CSA conducted by the inventors. Also provided are compositions comprising such immunogen polypeptides, and methods of using the immunogen polypeptides for vaccination and treatment of disease.
    Type: Application
    Filed: November 18, 2021
    Publication date: January 11, 2024
    Applicant: The United States of America,as represented by the Secretary,Department of Health and Human Services
    Inventors: Niraj H. Tolia, Rui Ma, Patrick E. Duffy, Jonathan P. Renn
  • Synthetic plasmodium antigens, compositions, and uses thereof
    Patent number: 11787845
    Abstract: Provided herein are synthetic P. vivax antigens, antibodies and pharmaceutical formulations and vaccines thereof. Also provided herein are methods of treating and/or preventing Plasmodium infection and/or disease by administering the synthetic P. vivax antigens, antibodies and pharmaceutical formulations and vaccines thereof.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: October 17, 2023
    Assignees: UNIVERSITY OF SOUTH FLORIDA, WASHINGTON UNIVERSITY, CASE WESTERN RESERVE UNIVERSITY
    Inventors: John H. Adams, Christopher L. King, Niraj H. Tolia, Edwin Chen, Nichole Diane Salinas, Miriam Thankam George, Francis B. Ntumngia, Samantha Jones Barnes
  • Synthetic plasmodium antigens, compositions, and uses thereof
    Patent number: 10927153
    Abstract: Provided herein are synthetic P. vivax antigens, antibodies and pharmaceutical formulations and vaccines thereof. Also provided herein are methods of treating and/or preventing Plasmodium infection and/or disease by administering the synthetic P. vivax antigens, antibodies and pharmaceutical formulations and vaccines thereof.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: February 23, 2021
    Assignees: University of South Florida, Washington University, Case Western Reserve University
    Inventors: John H. Adams, Christopher L. King, Niraj H. Tolia, Edwin Chen, Nichole Diane Salinas, Miriam Thankam George, Francis B. Ntumngia, Samantha Jones Barnes