Patents by Inventor Niranjan Kanesa-Thasan

Niranjan Kanesa-Thasan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccination Against Dengue Virus Infection
    Publication number: 20080193477
    Abstract: This invention relates to methods and kits for use in vaccination against dengue virus infection.
    Type: Application
    Filed: August 9, 2006
    Publication date: August 14, 2008
    Applicants: Acambis Inc., Sanofi Pasteur SA
    Inventors: Thomas P. Monath, Farshad Guirakhoo, Niranjan Kanesa-thasan, Thomas H. Ermak, Jean Lang, Remi Forrat
  • Multivalent dengue virus vaccine
    Patent number: 7217418
    Abstract: The present invention provides vaccine compositions of attenuated dengue virus. More specifically, the attenuated virus is produced by serial passage in PDK cells. The invention also provides methods for stimulating the immune system of an individual to induce protection against all four dengue virus serotypes by administration of attenuated dengue-1, dengue-2, dengue-3, and dengue-4 virus.
    Type: Grant
    Filed: July 24, 2003
    Date of Patent: May 15, 2007
    Assignee: United States of America as represented by the Secretary of the Army
    Inventors: Kenneth H. Eckels, Joseph B. Putnak, Doria R. Dubois, Bruce L. Innis, Charles H. Hoke, Wellington Sun, Niranjan Kanesa-Thasan
  • MULTIVALENT DENGUE VIRUS VACCINE
    Publication number: 20070087015
    Abstract: The present invention provides vaccine compositions of attenuated dengue virus. More specifically, the attenuated virus is produced by serial passage in PDK cells. The invention also provides methods for stimulating the immune system of an individual to induce protection against all four dengue virus serotypes by administration of attenuated dengue-1, dengue-2, dengue-3, and dengue-4 virus.
    Type: Application
    Filed: July 24, 2003
    Publication date: April 19, 2007
    Inventors: Kenneth Eckels, Joseph Putnak, Doria Dubois, Bruce Innis, Charles Hoke, Wellington Sun, Niranjan Kanesa-Thasan
  • Flavivirus detection and quantification assay
    Patent number: 6793488
    Abstract: A fluorescent DNA probes specific to the conserved terminal 3′-noncoding region (nucleotides 10653-10678) of dengue virus and a pair of flanking primers are designed to formulate a dengue specific fluorogenic polymerase chain reaction (PCR). Optimal assay conditions with zero background are disclosed which permit the detection of low levels of dengue virus from clinical specimens. Dengue virus isolates from different geographic regions can be universally detected and identified by the fluorogenic RT-PCR assay. Moreover, the assay is specific for dengue 2 virus and does not recognize other related flaviviruses, including dengue serotypes Louis encephalitis, yellow fever, and Kunjin viruses. The ) 3, and 4, Japanese encephalitis, St. assay also efficiently detected immunocomplexed dengue viruses. The fluorogenic RT-PCR assay readily detected viremia in sera collected from individuals ill with dengue fever.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: September 21, 2004
    Assignee: U.S. Army Medical Research & Materiel Command
    Inventors: Huo-Shu H. Houng, Niranjan Kanesa-Thasan