Patents by Inventor Niranjan Pandey

Niranjan Pandey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for identifying and preparing pharmaceutical agents for activating Tie1 and/or Tie2 receptors
    Patent number: 11674959
    Abstract: The present invention in various aspects and embodiments involves pharmaceutical compositions prepared by contacting a candidate ?- or ?-integrin-binding molecule, or panel thereof, with an integrin heterodimer, and quantifying heterodimer disruption by the candidate molecule. An integrin-binding molecule, or derivative thereof, that disrupts the integrin heterodimer is selected and is formulated into a pharmaceutical composition for administration to a subject, e.g., who has a disease or disorder related to abnormal vascularization.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: June 13, 2023
    Assignees: The Johns Hopkins University, AsclepiX Therapeutics, Inc.
    Inventors: Niranjan Pandey, Aleksander S. Popel, Jordan J. Green, Adam Mirando
  • USE OF TIGHT JUNCTION ANTAGONISTS TO TREAT INFLAMMATORY BOWEL DISEASE
    Publication number: 20160151449
    Abstract: The present invention provides materials and methods for the treatment of inflammatory bowel disease (e.g., Crohn's disease and ulcerative colitis). Materials of the invention may include compositions comprising one or more tight junction antagonists and optionally one or more therapeutic agents. Methods of the invention may comprise treating a subject in need thereof with a composition comprising one or more tight junction antagonists and, optionally one or more therapeutic agents.
    Type: Application
    Filed: February 3, 2016
    Publication date: June 2, 2016
    Inventors: Blake Paterson, Amir Tamiz, Niranjan Pandey
  • USE OF TIGHT JUNCTION ANTAGONISTS TO TREAT INFLAMMATORY BOWEL DISEASE
    Publication number: 20140296165
    Abstract: The present invention provides materials and methods for the treatment of inflammatory bowel disease (e.g., Crohn's disease and ulcerative colitis). Materials of the invention may include compositions comprising one or more tight junction antagonists and optionally one or more therapeutic agents. Methods of the invention may comprise treating a subject in need thereof with a composition comprising one or more tight junction antagonists and, optionally one or more therapeutic agents.
    Type: Application
    Filed: June 16, 2014
    Publication date: October 2, 2014
    Inventors: Blake Paterson, Amir Tamiz, Niranjan Pandey
  • Use of tight junction antagonists to treat inflammatory bowel disease
    Patent number: 8796203
    Abstract: The present invention provides materials and methods for the treatment of inflammatory bowel disease (e.g., Crohn's disease and ulcerative colitis). Materials of the invention may include compositions comprising one or more tight junction antagonists and optionally one or more therapeutic agents. Methods of the invention may comprise treating a subject in need thereof with a composition comprising one or more tight junction antagonists and, optionally one or more therapeutic agents.
    Type: Grant
    Filed: September 24, 2012
    Date of Patent: August 5, 2014
    Assignee: Alba Therapeutics Corporation
    Inventors: Blake Paterson, Amir Tamiz, Niranjan Pandey
  • Use Of Tight Junction Antagonists To Treat Inflammatory Bowel Disease
    Publication number: 20130102547
    Abstract: The present invention provides materials and methods for the treatment of inflammatory bowel disease (e.g., Crohn's disease and ulcerative colitis). Materials of the invention may include compositions comprising one or more tight junction antagonists and optionally one or more therapeutic agents. Methods of the invention may comprise treating a subject in need thereof with a composition comprising one or more tight junction antagonists and, optionally one or more therapeutic agents.
    Type: Application
    Filed: September 24, 2012
    Publication date: April 25, 2013
    Applicant: Alba Therapeutics Corp.
    Inventors: Blake Paterson, Amir Tamiz, Niranjan Pandey
  • Use of tight junction antagonists to treat inflammatory bowl disease
    Patent number: 8299017
    Abstract: The present invention provides materials and methods for the treatment of inflammatory bowel disease (e.g., Crohn's disease and ulcerative colitis). Materials of the invention may include compositions comprising one or more tight junction antagonists and optionally one or more therapeutic agents. Methods of the invention may comprise treating a subject in need thereof with a composition comprising one or more tight junction antagonists and, optionally one or more therapeutic agents.
    Type: Grant
    Filed: May 27, 2010
    Date of Patent: October 30, 2012
    Assignee: Alba Therapeutics Corp.
    Inventors: Blake Paterson, Amir Tamiz, Niranjan Pandey
  • USE OF TIGHT JUNCTION ANTAGONISTS TO TREAT INFLAMMATORY BOWL DISEASE
    Publication number: 20110136747
    Abstract: The present invention provides materials and methods for the treatment of inflammatory bowel disease (e.g., Crohn's disease and ulcerative colitis). Materials of the invention may include compositions comprising one or more tight junction antagonists and optionally one or more therapeutic agents. Methods of the invention may comprise treating a subject in need thereof with a composition comprising one or more tight junction antagonists and, optionally one or more therapeutic agents.
    Type: Application
    Filed: May 27, 2010
    Publication date: June 9, 2011
    Applicant: Alba Therapeutics Corporation
    Inventors: Blake Paterson, Amir Tamiz, Niranjan Pandey
  • USE OF TIGHT JUNCTION ANTAGONISTS TO TREAT INFLAMMATORY BOWEL DISEASE
    Publication number: 20090069247
    Abstract: The present invention provides materials and methods for the treatment of inflammatory bowel disease (e.g., Crohn's disease and ulcerative colitis). Materials of the invention may include compositions comprising one or more tight junction antagonists and optionally one or more therapeutic agents. Methods of the invention may comprise treating a subject in need thereof with a composition comprising one or more tight junction antagonists and, optionally one or more therapeutic agents.
    Type: Application
    Filed: October 9, 2007
    Publication date: March 12, 2009
    Inventors: Blake Paterson, Amir Tamiz, Niranjan Pandey
  • Thia-tetraazaacenaphthylene kinase inhibitors
    Publication number: 20070265264
    Abstract: The present invention is directed to novel thia-tetraazaacenaphthylene compounds of Formula (I): and pharmaceutically acceptable forms thereof and their synthesis and use as inhibitors of ATP-protein kinase interactions.
    Type: Application
    Filed: April 10, 2006
    Publication date: November 15, 2007
    Inventors: Kathleen Battista, Gilles Bignan, Peter Connolly, Stuart Hayden, Sigmond Johnson, Ronghui Lin, Niranjan Pandey, Mark Powell
  • SUBSTITUTED THIATRIAZAACENAPHTHYLENE-6-CARBONITRILE KINASE INHIBITORS
    Publication number: 20070225309
    Abstract: The present invention is directed to substituted thiatriazaacenaphthylene-6-carbonitrile compounds of formula (I): and forms thereof, their synthesis and use for treating, preventing or ameliorating a chronic or acute protein kinase mediated disease, disorder or condition.
    Type: Application
    Filed: February 7, 2007
    Publication date: September 27, 2007
    Inventors: Peter Connolly, Stuart Emanuel, Stuart Hayden, Sigmond Johnson, Bharat Lagu, Steven Middleton, Niranjan Pandey, Mark Powell
  • Thiazolopyrimidine kinase inhibitors
    Publication number: 20070185139
    Abstract: The present invention is directed to novel thiazolopyrimidine compounds of Formula (I) or a form or composition thereof and the thereof as inhibitors of ATP-protein kinase interactions.
    Type: Application
    Filed: August 2, 2006
    Publication date: August 9, 2007
    Inventors: Eva Binnun, Peter Connolly, Sigmond Johnson, Ronghui Lin, Steven Middleton, Sandra Moreno-Mazza, Niranjan Pandey, Steven Wetter
  • Thiazolopyridine kinase inhibitors
    Publication number: 20060058341
    Abstract: The present invention is directed to novel thiazolopyridines, pharmaceutical compositions thereof, and the use thereof as inhibitors of ATP-protein kinase interactions.
    Type: Application
    Filed: September 15, 2005
    Publication date: March 16, 2006
    Inventors: Peter Connolly, Sigmond Johnson, Niranjan Pandey, Steven Middleton