Patents by Inventor Niranjana POKHAREL

Niranjana POKHAREL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinolin-2(1H)-one inhibitors of Late SV40 Factor
    Patent number: 11458132
    Abstract: The present invention is directed to compositions, methods and kits for treatment of cancer, e.g., hepatocellular carcinoma (HCC). In some embodiments, the present invention discloses the use of a small-molecule compounds of Formula (I) to inhibit tubulin acetylation, to inhibit cell migration, or to modulate cell compaction.
    Type: Grant
    Filed: September 1, 2021
    Date of Patent: October 4, 2022
    Assignee: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: Scott Edward Schaus, Ulla Hansen, Emily Ann York, Niranjana Pokharel
  • HETEROCYCLIC LSF INHIBITORS AND THEIR USES
    Publication number: 20220112206
    Abstract: The present invention is directed to heterocyclic SV40 Factor (LSF) inhibitors and their uses. In some implementations, the present invention discloses small-molecule compounds of Formula (I). In some implementations, the compounds of Formula (I) are used in methods for inhibiting LSF in a subject. In some implementations, the compounds of Formula (I) are used in methods for treating cancer in a subject.
    Type: Application
    Filed: December 22, 2021
    Publication date: April 14, 2022
    Applicant: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: Scott E. SCHAUS, Ulla HANSEN, John A. KAVOURIS, Emily A. YORK, Niranjana POKHAREL
  • QUINOLIN-2(1H)-ONE INHIBITORS OF LATE SV40 FACTOR
    Publication number: 20220062272
    Abstract: The present invention is directed to compositions, methods and kits for treatment of cancer, e.g., hepatocellular carcinoma (HCC). In some embodiments, the present invention discloses the use of a small-molecule compounds of Formula (I) to inhibit tubulin acetylation, to inhibit cell migration, or to modulate cell compaction.
    Type: Application
    Filed: September 1, 2021
    Publication date: March 3, 2022
    Applicant: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: Scott Edward SCHAUS, Ulla HANSEN, Emily Ann YORK, Niranjana POKHAREL
  • Heterocyclic LSF inhibitors and their uses
    Patent number: 11242353
    Abstract: The present invention is directed to heterocyclic SV40 Factor (LSF) inhibitors and their uses. In some implementations, the present invention discloses small-molecule compounds of Formula (I). In some implementations, the compounds of Formula (I) are used in methods for inhibiting LSF in a subject. In some implementations, the compounds of Formula (I) are used in methods for treating cancer in a subject.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: February 8, 2022
    Assignee: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: Scott E. Schaus, Ulla Hansen, John A. Kavouris, Emily A. York, Niranjana Pokharel
  • HETEROCYCLIC LSF INHIBITORS AND THEIR USES
    Publication number: 20210230173
    Abstract: The present invention is directed to heterocyclic SV40 Factor (LSF) inhibitors and their uses. In some implementations, the present invention discloses small-molecule compounds of Formula (I). In some implementations, the compounds of Formula (I) are used in methods for inhibiting LSF in a subject. In some implementations, the compounds of Formula (I) are used in methods for treating cancer in a subject.
    Type: Application
    Filed: January 22, 2021
    Publication date: July 29, 2021
    Applicant: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: Scott E. SCHAUS, Ulla HANSEN, John A. KAVOURIS, Emily A. YORK, Niranjana POKHAREL