Patents by Inventor Nirav A. Dhanesha

Nirav A. Dhanesha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF INHIBITING INTEGRIN ALPHA9BETA1 ACTIVITY
    Publication number: 20240115653
    Abstract: The invention provides a method and kits for inhibiting integrin ?9?1 activity comprising contacting integrin ?9?1 or a binding partner of integrin ?9?1 with an isolated anti-integrin ?9 inhibitor, wherein the integrin ?9?1 activity is inhibited. In certain aspects, the present invention provides a novel intervention by targeting integrin ?9?1 with a functional blocking inhibitor (e.g., peptides or antibodies) to limit brain damage following reperfusion after ischemic stroke.
    Type: Application
    Filed: October 13, 2023
    Publication date: April 11, 2024
    Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Anil K. Chauhan, Nirav A. Dhanesha
  • Methods of inhibiting integrin ?9?1 activity
    Patent number: 11806382
    Abstract: The invention provides a method and kits for inhibiting integrin ?9?1 activity comprising contacting integrin ?9?1 or a binding partner of integrin ?9?1 with an isolated anti-integrin ?9 inhibitor, wherein the integrin ?9?1 activity is inhibited. In certain aspects, the present invention provides a novel intervention by targeting integrin ?9?1 with a functional blocking inhibitor (e.g., peptides or antibodies) to limit brain damage following reperfusion after ischemic stroke.
    Type: Grant
    Filed: November 18, 2020
    Date of Patent: November 7, 2023
    Assignee: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Anil K. Chauhan, Nirav A. Dhanesha
  • METHODS OF INHIBITING INTEGRIN ALPHA9BETA1 ACTIVITY
    Publication number: 20210147556
    Abstract: The invention provides a method and kits for inhibiting integrin ?9?1 activity comprising contacting integrin ?9?1 or a binding partner of integrin ?9?1 with an isolated anti-integrin ?9 inhibitor, wherein the integrin ?9?1 activity is inhibited. In certain aspects, the present invention provides a novel intervention by targeting integrin ?9?1 with a functional blocking inhibitor (e.g., peptides or antibodies) to limit brain damage following reperfusion after ischemic stroke.
    Type: Application
    Filed: November 18, 2020
    Publication date: May 20, 2021
    Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Anil K. Chauhan, Nirav A. Dhanesha