Patents by Inventor Nirbhai Singh

Nirbhai Singh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for the Intracellular Disruption of VEGF and VEGFR-2 by Intraceptors
    Publication number: 20180141995
    Abstract: The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention further provides pharmaceutical compositions, and methods of use thereof for the treatment and prevention of an angiogenesis-related condition using said intraceptors. The invention further provides for nucleic acids encoding said intraceptors.
    Type: Application
    Filed: September 19, 2016
    Publication date: May 24, 2018
    Applicants: Medical College of Georgia Research Institute, University of Utah Research Foundation
    Inventors: Balamurali Ambati, Nirbhai Singh, Shivan Amin
  • Compositions and methods for the intracellular disruption of VEGF and VEGFR-2 by intraceptors
    Patent number: 9447166
    Abstract: The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention further provides pharmaceutical compositions, and methods of use thereof, for the treatment and prevention of an angiogenesis-related condition using said intraceptors. The invention further provides for nucleic acids encoding said intraceptors.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: September 20, 2016
    Assignees: Medical College of Georgia Research Institute, University of Utah Research Foundation
    Inventors: Balamurali Ambati, Nirbhai Singh, Shivan Amin
  • Modulation of angiogenesis
    Patent number: 9198981
    Abstract: This invention relates to compounds, compositions, and methods for the treatment of traits, diseases and conditions that respond to the modulation of angiogenic growth factor bioavailability or biological activity.
    Type: Grant
    Filed: October 17, 2006
    Date of Patent: December 1, 2015
    Assignee: The University of Kentucky
    Inventors: Balamurali Krishna Ambati, Jayakrishna Ambati, Nirbhai Singh
  • Compositions and Methods for the Intracellular Disruption of VEGF and VEGFR-2 by Intraceptors
    Publication number: 20140329888
    Abstract: The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention further provides pharmaceutical compositions, and methods of use thereof, for the treatment and prevention of an angiogenesis-related condition using said intraceptors. The invention further provides for nucleic acids encoding said intraceptors.
    Type: Application
    Filed: March 31, 2014
    Publication date: November 6, 2014
    Inventors: Balamurali Ambati, Nirbhai Singh, Shivan Amin
  • Compositions and Methods for the Intracellular Disruption of VEGF and VEGFR-2 by Intraceptors
    Publication number: 20130130980
    Abstract: The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention further provides pharmaceutical compositions, and methods of use thereof, for the treatment and prevention of an angiogenesis-related condition using said intraceptors. The invention further provides for nucleic acids encoding said intraceptors.
    Type: Application
    Filed: July 2, 2012
    Publication date: May 23, 2013
    Inventors: Balamurali Ambati, Nirbhai Singh, Shivan Amin
  • Compositions and methods for the intracellular disruption of VEGF and VEGFR-2 by intraceptors
    Patent number: 8211864
    Abstract: The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention further provides pharmaceutical compositions, and methods of use thereof, for the treatment and prevention of an angiogenesis-related condition using said intraceptors. The invention further provides for nucleic acids encoding said intraceptors.
    Type: Grant
    Filed: January 26, 2006
    Date of Patent: July 3, 2012
    Assignees: Medical College of Georgia Research Institute, University of Utah Research Foundation
    Inventors: Balamurali Ambati, Nirbhai Singh, Shivan Amin
  • Compositions and Methods for the Intracellular Disruption of Vegf and Vegfr-2 By Intraceptors
    Publication number: 20080318857
    Abstract: The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention further provides pharmaceutical compositions, and methods of use thereof, for the treatment and prevention of an angiogenesis-related condition using said intraceptors. The invention further provides for nucleic acids encoding said intraceptors.
    Type: Application
    Filed: January 26, 2006
    Publication date: December 25, 2008
    Inventors: Balamurali Ambati, Nirbhai Singh, Shivan Amin
  • Modulation of angiogenesis
    Publication number: 20070191273
    Abstract: This invention relates to compounds, compositions, and methods for the treatment of traits, diseases and conditions that respond to the modulation of angiogenic growth factor bioavailability or biological activity.
    Type: Application
    Filed: October 17, 2006
    Publication date: August 16, 2007
    Applicant: The University of Kentucky Research Foundation
    Inventors: Balamurali Krishna Ambati, Jayakrishna Ambati, Nirbhai Singh