Patents by Inventor Nirmal Janardhanan
Nirmal Janardhanan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11835613Abstract: For reconstruction of an image in MRI, unsupervised training (i.e., data-driven) based on a scan of a given patient is used to reconstruct model parameters, such as estimating values of a contrast model and a motion model based on fit of images generated by the models for different readouts and times. The models and the estimated values from the scan-specific unsupervised training are then used to generate the patient image for that scan. This may avoid artifacts from binning different readouts together while allowing for scan sequences using multiple readouts.Type: GrantFiled: January 11, 2022Date of Patent: December 5, 2023Assignee: Siemens Healthcare GmbHInventors: Boris Mailhe, Dorin Comaniciu, Simon Arberet, Nirmal Janardhanan, Mariappan S. Nadar, Hongki Lim, Mahmoud Mostapha
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Publication number: 20230221392Abstract: For reconstruction of an image in MRI, unsupervised training (i.e., data-driven) based on a scan of a given patient is used to reconstruct model parameters, such as estimating values of a contrast model and a motion model based on fit of images generated by the models for different readouts and times. The models and the estimated values from the scan-specific unsupervised training are then used to generate the patient image for that scan. This may avoid artifacts from binning different readouts together while allowing for scan sequences using multiple readouts.Type: ApplicationFiled: January 11, 2022Publication date: July 13, 2023Inventors: Boris Mailhe, Dorin Comaniciu, Simon Arberet, Nirmal Janardhanan, Mariappan S. Nadar, Hongki Lim, Mahmoud Mostapha
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Publication number: 20230108663Abstract: For magnetic resonance (MR) reconstruction using artificial intelligence (AI), the AI-based reconstruction for MR imaging systems is offloaded to one or more servers. A remote server performs AI-based reconstruction. A library of recent, old, custom, and/or publicly available AI-based reconstruction processes may be rapidly deployed and available to the server, which has the memory and processing resources for AI-based reconstruction. Load balancing of the data and/or between servers may improve performance.Type: ApplicationFiled: October 6, 2021Publication date: April 6, 2023Inventors: Nirmal Janardhanan, Laszlo Lazar, Boris Mailhe, Simon Arberet, Mariappan S. Nadar, Dorin Comaniciu, Kelvin Chow, Michael Bush
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Publication number: 20230093752Abstract: One or more tractograms of a global tractography of a tissue of interest are determined. At least one instance of diffusion magnetic resonance imaging data of the tissue of interest is obtained. A trained machine-learning algorithm generates the one or more tractograms based on the at least one instance of the diffusion magnetic resonance imaging data.Type: ApplicationFiled: September 8, 2022Publication date: March 23, 2023Inventors: Mahmoud Mostapha, Boris Mailhe, Dorin Comaniciu, Nirmal Janardhanan, Simon Arberet, Hongki Lim, Mariappan S. Nadar
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Patent number: 11435419Abstract: For radial sampling in magnetic resonance imaging (MRI), a rescaling factor is determined from k-space data for each coil. The rescale factor is inversely proportional to the streak energy in the k-space data. The k-space data from the coils is rescaled for reconstruction, such as weighting the k-space data by the rescale factor in a data consistency term of iterative reconstruction. The rescale factor is additionally or alternatively used to determine a correction field for correction of intensity bias applied to intensities in the image-object space after reconstruction. These approaches may result in a diagnostically useful bias-corrected image with reduced streak artifact while benefiting from the efficient computation (i.e., computer operates to reconstruct more quickly).Type: GrantFiled: May 10, 2018Date of Patent: September 6, 2022Assignee: Siemens Healthcare GmbHInventors: Sajan Goud Lingala, Boris Mailhe, Nirmal Janardhanan, Jyotipriya Das, Robert Grimm, Marcel Dominik Nickel, Mariappan S. Nadar
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Publication number: 20220215600Abstract: A computer-implemented method includes, based on an input dataset defining an input image, determining a reconstructed image using a reconstruction algorithm, and executing a data-consistency operation for enforcing consistency between the input image and the reconstructed image. The data-consistency operation determines, for multiple K-space positions at which the input dataset comprises respective source data, a contribution of respective K-space values associated with the input dataset to a K-space representation of the reconstructed image.Type: ApplicationFiled: December 7, 2021Publication date: July 7, 2022Inventors: Simon Arberet, Mariappan S. Nadar, Boris Mailhe, Mahmoud Mostapha, Nirmal Janardhanan
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Patent number: 10914798Abstract: A method for estimating a coil sensitivity map for a magnetic resonance (MR) image includes providing a matrix A of sliding blocks of a 3D image of coil calibration data, calculating a left singular matrix V? from a singular value decomposition of A corresponding to ? leading singular values, calculating P=V?V?H, calculating a matrix that is an inverse Fourier transform of a zero-padded matrix P, and solving MHcr=(Sr)Hcr for cr, where cr is a vector of coil sensitivity maps for all coils at spatial location r, and M = ( ( 1 1 … 1 0 0 … 0 … … … 0 0 … 0 ) ? ( 0 0 … 0 1 1 … 1 … … … 0 0 … 0 ) ? ? … ? ? ( 0 0 … 0 0 0 … 0 … … … 1 1 … 1 ) ) .Type: GrantFiled: September 27, 2013Date of Patent: February 9, 2021Assignee: Siemens Healthcare GmbHInventors: Jun Liu, Hui Xue, Marcel Dominik Nickel, Ti-chiun Chang, Mariappan S. Nadar, Alban Lefebvre, Edgar Mueller, Qiu Wang, Zhili Yang, Nirmal Janardhanan, Michael Zenge
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Publication number: 20190346518Abstract: For radial sampling in magnetic resonance imaging (MRI), a rescaling factor is determined from k-space data for each coil. The rescale factor is inversely proportional to the streak energy in the k-space data. The k-space data from the coils is rescaled for reconstruction, such as weighting the k-space data by the rescale factor in a data consistency term of iterative reconstruction. The rescale factor is additionally or alternatively used to determine a correction field for correction of intensity bias applied to intensities in the image-object space after reconstruction. These approaches may result in a diagnostically useful bias-corrected image with reduced streak artifact while benefiting from the efficient computation (i.e., computer operates to reconstruct more quickly).Type: ApplicationFiled: May 10, 2018Publication date: November 14, 2019Inventors: Sajan Goud Lingala, Boris Mailhe, Nirmal Janardhanan, Jyotipriya Das, Robert Grimm, Marcel Dominik Nickel, Mariappan S. Nadar
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Patent number: 9482732Abstract: A method of image reconstruction for a magnetic resonance imaging (MRI) system includes obtaining k-space scan data captured by the MRI system, the k-space scan data being representative of an undersampled region over time, iteratively reconstructing preliminary dynamic images for the undersampled region from the k-space scan data via optimization of a first instance of a minimization problem, the minimization problem including a regularization term weighted by a weighting parameter array, generating a motion determination indicative of an extent to which each location of the undersampled region exhibits motion over time based on the preliminary dynamic images, and iteratively reconstructing motion-compensated dynamic images for the region from the k-space scan data via optimization of a second instance of the minimization problem, the second instance having the weighting parameter array altered as a function of the motion determination.Type: GrantFiled: October 29, 2013Date of Patent: November 1, 2016Inventors: Nicolas Chesneau, Nirmal Janardhanan, Jun Liu, Mariappan S. Nadar, Qiu Wang, Zhili Yang
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Patent number: 9097780Abstract: A computer-implemented method for reconstruction of a magnetic resonance image includes acquiring a first incomplete k-space data set comprising a plurality of first k-space lines spaced according to an acceleration factor and one or more calibration lines. A parallel imaging reconstruction technique is applied to the first incomplete k-space data to determine a plurality of second k-space lines not included in the first incomplete k-space data set, thereby yielding a second incomplete k-space data set. Then, the parallel imaging reconstruction technique is applied to the second incomplete k-space data to determine a plurality of third k-space lines not included in the second incomplete k-space data, thereby yielding a complete k-space data set.Type: GrantFiled: October 15, 2013Date of Patent: August 4, 2015Assignee: Siemens AktiengesellschaftInventors: Jun Liu, Zhili Yang, Mariappan S. Nadar, Nirmal Janardhanan, Michael Zenge, Edgar Mueller, Qiu Wang, Axel Loewe
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Publication number: 20140133724Abstract: A computer-implemented method for reconstruction of a magnetic resonance image includes acquiring a first incomplete k-space data set comprising a plurality of first k-space lines spaced according to an acceleration factor and one or more calibration lines. A parallel imaging reconstruction technique is applied to the first incomplete k-space data to determine a plurality of second k-space lines not included in the first incomplete k-space data set, thereby yielding a second incomplete k-space data set. Then, the parallel imaging reconstruction technique is applied to the second incomplete k-space data to determine a plurality of third k-space lines not included in the second incomplete k-space data, thereby yielding a complete k-space data set.Type: ApplicationFiled: October 15, 2013Publication date: May 15, 2014Applicants: Siemens Aktiengesellschaft, Siemens CorporationInventors: Jun Liu, Zhili Yang, Mariappan S. Nadar, Nirmal Janardhanan, Michael Zenge, Edgar Mueller, Qiu Wang, Axel Loewe
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Publication number: 20140126796Abstract: A method of image reconstruction for a magnetic resonance imaging (MRI) system includes obtaining k-space scan data captured by the MRI system, the k-space scan data being representative of an undersampled region over time, iteratively reconstructing preliminary dynamic images for the undersampled region from the k-space scan data via optimization of a first instance of a minimization problem, the minimization problem including a regularization term weighted by a weighting parameter array, generating a motion determination indicative of an extent to which each location of the undersampled region exhibits motion over time based on the preliminary dynamic images, and iteratively reconstructing motion-compensated dynamic images for the region from the k-space scan data via optimization of a second instance of the minimization problem, the second instance having the weighting parameter array altered as a function of the motion determination.Type: ApplicationFiled: October 29, 2013Publication date: May 8, 2014Applicant: SIEMENS CORPORATIONInventors: Nicolas Chesneau, Nirmal Janardhanan, Jun Liu, Mariappan S. Nadar, Qiu Wang, Zhili Yang
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Publication number: 20140088899Abstract: A method for estimating a coil sensitivity map for a magnetic resonance (MR) image includes providing a matrix A of sliding blocks of a 3D image of coil calibration data, calculating a left singular matrix V? from a singular value decomposition of A corresponding to ? leading singular values, calculating P=V?V?H, calculating a matrix S that is an inverse Fourier transform of a zero-padded matrix P, and solving MHcr=(Sr)Hcr for cr, where cr is a vector of coil sensitivity maps for all coils at spatial location r, and M = ( ( 1 1 … 1 0 0 … 0 … … … 0 0 … 0 ) ? ( 0 0 … 0 1 1 … 1 … … … 0 0 … 0 ) ? ? … ? ? ( 0 0 … 0 0 0 … 0 … … … 1 1 … 1 ) ) .Type: ApplicationFiled: September 27, 2013Publication date: March 27, 2014Applicants: SIEMENS AKTIENGESELLSCHAFT, SIEMENS CORPORATIONInventors: Jun Liu, Hui Xue, Marcel Dominik Nickel, Ti-chiun Chang, Mariappan S. Nadar, Alban Lefebvre, Edgar Mueller, Qiu Wang, Zhili Yang, Nirmal Janardhanan, Michael Zenge
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Publication number: 20130289912Abstract: A method for estimating a coil sensitivity map for a magnetic resonance (MR) image includes providing (61) a matrix A of sliding blocks of a 2D image of coil calibration data, calculating (62) a left singular matrix V? from a singular value decomposition of A corresponding to ? leading singular values, calculating (63) P=V?V?H, calculating (64) a matrix S that is an inverse Fourier transform of a zero-padded matrix P, and solving (65) MHcr=(Sr)Hcr for cr, where cr is a vector of coil sensitivity maps for all coils at spatial location r, and M ? ( ( 1 1 … 1 0 0 … 0 … … … 0 0 … 0 ) ? ( 0 0 … 0 1 1 … 1 … … … 0 0 … 0 ) ? ? … ? ? ( 0 0 … 0 0 0 … 0 … … … 1 1 … 1 ) ) .Type: ApplicationFiled: February 28, 2013Publication date: October 31, 2013Applicants: Siemens Aktiengesellschaft, Siemens CorporationInventors: Jun Liu, Hui Xue, Marcel Dominik Nickel, Ti-chiun Chang, Mariappan S. Nadar, Alban Lefebvre, Edgar Mueller, Qiu Wang, Zhili Yang, Nirmal Janardhanan, Michael Zenge