Abstract: Image-guided navigation for spinal cord treatments and therapies are described. The image-guided navigation is augmented with anatomical measurement data related to spinal cord and vertebral anatomy. From these data and medical image data, an augmented model of spinal cord anatomy is generated and/or navigation data can be generated for localizing spinal cord structures, such as by mapping the anatomical measurement data to the medical image data. The augmented model data and/or navigation data can be used for surgical navigation, stimulation parameter setting, electrode configuration selection, pre-surgical planning, surgical visualization, and so on.