Abstract: An information system provides a conversational knowledge base for responding to user queries. The information system incorporates contemporaneous advancements in NLP and deep learning to create the conversation knowledge base from its documents, which may be obtained from various sources. Domain-specific information is extracted and generated from the documents substantially without human intervention. From the domain-specific information, precise answers to synthesized questions are generated using transformer-based deep learning models.

Abstract: Aspects of the present disclosure provide methods, devices, and computer-readable storage media that support adaptive scheduling of electric vehicles (EVs) of an EV fleet for order deliveries. In some implementations, one or more aspects of the adaptive EV scheduling may be customized for EVs. For example, the adaptive EV scheduling may include identifying an energy efficient route that also reduces stress on a battery of an EV and may be based at least in part on a charging parameter associated with the EV. In some examples, the charging parameter may include one or more of a state of charge (SOC) associated with the battery, a state of health (SOH) associated with the battery, a location of a charging station for the EV, an average charging duration associated with the EV, or an intelligent charging parameter associated with the EV.

Abstract: Disclosed are various embodiments of a stateful network router. In one embodiment, a network data connection is intercepted between a first host and a second host on a network. First data packets from the network data connection sent by the first host to the second host are routed to a target network appliance. Second data packets from the network data connection sent by the second host to the first host are also to the target network appliance.

Abstract: Techniques are described that enable users to configure the mirroring of network traffic sent to or received by computing resources associated with a virtual network of computing resources at a service provider network. The mirrored network traffic can be used for many different purposes including, for example, network traffic content inspection, forensic and threat analysis, network troubleshooting, data loss prevention, and the like. Users can configure such network traffic mirroring without the need to manually install and manage network capture agents or other such processes on each computing resource for which network traffic mirroring is desired. Users can cause mirrored network traffic to be stored at a storage service in the form of packet capture (or “pcap”) files, which can be used by any number of available out-of-band security and monitoring appliances including other user-specific monitoring tools and/or other services of the service provider network.

Abstract: Disclosed are various embodiments for a container execution environment. In one embodiment, a container is executed in a virtual machine instance running on a computing device. A container control plane is executed separately from the virtual machine instance in an off-load device operably coupled to the computing device via a hardware interconnect interface. The container is managed using the container control plane executing on the off-load device.

Abstract: Techniques are described that enable users to configure the mirroring of network traffic sent to or received by computing resources associated with a virtual network of computing resources at a service provider network. The mirrored network traffic can be used for many different purposes including, for example, network traffic content inspection, forensic and threat analysis, network troubleshooting, data loss prevention, and the like. Users can configure such network traffic mirroring without the need to manually install and manage network capture agents or other such processes on each computing resource for which network traffic mirroring is desired. Users can cause mirrored network traffic to be stored at a storage service in the form of packet capture (or “pcap”) files, which can be used by any number of available out-of-band security and monitoring appliances including other user-specific monitoring tools and/or other services of the service provider network.

Abstract: Aspects of the present disclosure provide systems, methods, and computer-readable storage media that support optimized product design processes. During the design process, information identifying a set of features for a product design are received and evaluated against machine learning logic to identify a set of components that includes components corresponding to the set of features. One or more candidate components may be identified as alternatives to one or more set of components based on the characteristics, and modifications to optimize (e.g., reduce cost, weight, etc.) the set of components may be determined based on at least one design metric and the one or more candidate components. A final set of components that are optimized with respect to the at least one design metric may be output.

Abstract: Methods, systems, and computer-readable media for job scheduling based on job execution history are disclosed. A request is received to schedule a workload comprising a plurality of jobs. A resource allocation score for the workload is determined. The resource allocation score represents (at least in part) an estimated likelihood of successful execution of the workload. A first portion of the workload is scheduled for execution, and a remaining portion (if any) of the workload is delayed. A quantity of jobs in the first portion of the workload is determined based (at least in part) on the resource allocation score. Execution of the first portion of the workload is initiated.

Abstract: A first virtualization control mode to be used for configuring one or more compute instances is determined. Based at least partly on the mode, preparatory configuration operations for launching a compute instance are initiated. The operations include transferring at least a portion of a machine image to a storage device accessible from a host, and initialization of a virtual network interface. A compute instance is instantiated using the machine image at the host. The compute instance is a thread of an intermediary process launched by an administrative agent at the host in response to a launch request.

Abstract: Methods, systems, and computer-readable media for job execution with managed compute environments are disclosed. A specification of a managed compute environment comprises one or more constraints associated with computing resources in the managed compute environment. A queue or other data structure that is associated with the managed compute environment is monitored. The data structure is configured to store jobs. Data indicative of a job is detected in the data structure. One or more computing resources are reserved for the job from a pool of available computing resources. The one or more computing resources are selected for the job based at least in part on the one or more constraints associated with computing resources in the managed compute environment. Execution of the job using the one or more computing resources is initiated.

Abstract: Techniques for failover management using availability groups are described. According to some embodiments, customers can define one or more availability groups within their infrastructure. Each availability group may be associated with one or more rules which describe how the availability group should fail over. The availability group definition may define the resources included in the availability group, a target region to fail over to, and capacity reservations for the availability group in the target region. In some embodiments, the definition may also include a replication frequency for storage resources which defines how often data is backed up. Once a customer as created an availability group the customer is then able to either create resources in that availability group or associate already existing resources with the availability group. An availability group management service can ensure that data, capacity reservations and network infrastructure are defined and/or replicated to the target location.

Abstract: Systems and methods for facilitating an identification of an application that runs on a platform are provided.

Abstract: The invention provides novel anti-VISTA antibodies, pharmaceutical compositions comprising such antibodies, and therapeutic methods of using such antibodies and pharmaceutical compositions for the treatment of diseases such as cancer.

Abstract: Methods, systems, and computer-readable media for job execution with managed compute environments are disclosed. A specification of a managed compute environment comprises one or more constraints associated with computing resources in the managed compute environment. A queue or other data structure that is associated with the managed compute environment is monitored. The data structure is configured to store jobs. Data indicative of a job is detected in the data structure. One or more computing resources are reserved for the job from a pool of available computing resources. The one or more computing resources are selected for the job based at least in part on the one or more constraints associated with computing resources in the managed compute environment. Execution of the job using the one or more computing resources is initiated.

Abstract: A new product development system may provide, to one or more client devices and server devices, one or more tools to enable development of a new product. The new product development system may receive current project data identifying a current project for developing the new product, historical project data identifying historical projects for developing historical products, and industry data associated with the new product. The new product development system may process the current project data, the historical project data, and the industry data, with a machine learning model, to identify one or more variables for a predictive model and may process the one or more variables, with the predictive model, to predict a predicted success rate of the current project. The new product development system may perform one or more actions based on the predicted success rate of the current project.

Abstract: An administrative agent running at a virtualization host of a network-accessible virtualized computing service determines that a first virtual machine is to be instantiated. The agent initiates at least a first configuration operation to enable connectivity for at least a portion of network traffic associated with the first virtual machine. The first configuration operation is performed at least in part using a first virtualization offloading card of the virtualization host. The agent causes a virtualization intermediary process of the virtualization host to launch one or more execution threads of the virtualization intermediary process to implement the first virtual machine. The intermediary process may be swapped to persistent storage, e.g., based on an analysis of resources of the virtualization host.

Abstract: A number of cells of a control plane of a virtualized computing service are set up, including a first cell with one or more request processing nodes, a local instance of a data store, and metadata indicating a set of virtualization hosts. A request processer transmits a request for a virtual machine to the first cell. A request processor of the cell initiates a workflow to launch the virtual machine using a virtualization host; the workflow includes storing a record of the request in the local instance of the data store.

Abstract: A surgical instrument (10) includes a handle assembly (20), an elongate body portion (50) extending from the handle assembly (20) and defining a longitudinal axis, and a rotation assembly (100) rotatably securing the elongate body portion (50) to the handle assembly (20). The rotation assembly (100) includes a sleeve member (110) and a rotation knob (120) supported about the sleeve member (110). The rotation knob (120) is movable relative to the sleeve member (110) and the handle assembly (20) along the longitudinal axis.

Abstract: Disclosed are various embodiments of a stateful network router. In one embodiment, a stateful network router intercepts a network data connection between a first host and a second host on a network. The stateful network router routes first data packets from the network data connection sent by the first host to the second host to a target. The stateful network router also routes second data packets from the network data connection sent by the second host to the first host to the target.

Abstract: A first virtualization control mode to be used for configuring one or more compute instances is determined. Based at least partly on the mode, preparatory configuration operations for launching a compute instance are initiated. The operations include transferring at least a portion of a machine image to a storage device accessible from a host, and initialization of a virtual network interface. A compute instance is instantiated using the machine image at the host. The compute instance is a thread of an intermediary process launched by an administrative agent at the host in response to a launch request.