Patents by Inventor Nissi Varki

Nissi Varki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD AND DEVICE FOR DETECTING SIGLEC12
    Publication number: 20200003779
    Abstract: The present application is in the field of sialic acid biochemistry, metabolism and antigenicity. More particularly, the present invention relates to the detection and analysis of Siglec-XII in a human biological sample for risk prediction, prognostication and diagnosis of disease. Also provided are devices configured to perform the methods disclosed herein.
    Type: Application
    Filed: August 27, 2019
    Publication date: January 2, 2020
    Inventors: Ajit Varki, Nissi Varki, Andrea Verhagen, Shoib Siddiqui
  • Methods For Detecting And Analyzing N-Glycolylneuraminic Acid (NEU5GC) In Biological Materials
    Publication number: 20120142903
    Abstract: The present application is in the field of sialic acid chemistry, metabolism and antigenicity. More particularly, the present invention relates to the detection and analysis of the non-human sialic acid, N-glycolylneuraminic acid (Neu5Gc) in biological materials, such as food and clinical specimens. Such detection and analysis is facilitated by the use of Neu5Gc specific antibodies. The present invention also relates to the detection of antiNeu5Gc antibodies in clinical samples, as well as the production of anti-Neu5Gc specific antibodies.
    Type: Application
    Filed: November 28, 2011
    Publication date: June 7, 2012
    Inventors: Ajit Varki, Pam Tangvoranuntakul, Nissi Varki, Elaine Muchmore
  • Methods for detecting and analyzing N-glycolylneuraminic acid (Neu5Gc) in biological materials
    Patent number: 8084219
    Abstract: The present application is in the field of sialic acid chemistry, metabolism and antigenicity. More particularly, the present invention relates to the detection and analysis of the non-human sialic acid, N-glycolylneuraminic acid (Neu5Gc) in biological materials, such as food and clinical specimens. Such detection and analysis is facilitated by the use of Neu5Gc specific antibodies. The present invention also relates to the detection of antiNeu5Gc antibodies in clinical samples, as well as the production of anti-Neu5Gc specific antibodies.
    Type: Grant
    Filed: March 17, 2010
    Date of Patent: December 27, 2011
    Assignee: The Regents of the University of California
    Inventors: Ajit Varki, Pam Tangvoranuntakul, Nissi Varki, Elaine Muchmore
  • Novel Ligand Involved In The Transmigration Of Leukocytes Across the Endothelium and Uses Therefor
    Publication number: 20100249383
    Abstract: The present invention provides methods and compositions involved in the inflammatory response, as well as various pathological processes. In particular, the present invention provides novel antibodies directed against novel glycans that are enriched on endothelial cell surfaces. In addition, the present invention provides methods and compositions involved in a previously unrecognized pathway of the inflammatory response and various pathological processes. In addition the present invention provides methods and compositions suitable to mediate the inflammatory response in various settings, as well as methods and compositions for the identification of other inflammatory response mediators.
    Type: Application
    Filed: July 13, 2009
    Publication date: September 30, 2010
    Inventors: Hudson Freeze, Geetha Srikrishna, Ajit Varki, Nissi Varki
  • Methods for Detecting and Analyzing N-Glycolylneuraminic Acid (Neu5Gc) In Biological Materials
    Publication number: 20100221770
    Abstract: The present application is in the field of sialic acid chemistry, metabolism and antigenicity. More particularly, the present invention relates to the detection and analysis of the non-human sialic acid, N-glycolylneuraminic acid (Neu5Gc) in biological materials, such as food and clinical specimens. Such detection and analysis is facilitated by the use of Neu5Gc specific antibodies. The present invention also relates to the detection of antiNeu5Gc antibodies in clinical samples, as well as the production of anti-Neu5Gc specific antibodies.
    Type: Application
    Filed: March 17, 2010
    Publication date: September 2, 2010
    Inventors: Ajit Varki, Pam Tangvoranuntakul, Nissi Varki, Elaine Muchmore, Pascal Gagneux, Sandra Diaz
  • Methods for detecting and analyzing N-glycolylneuraminic acid (Neu5Gc) in biological materials
    Patent number: 7682794
    Abstract: The present application is in the field of sialic acid chemistry, metabolism and antigenicity. More particularly, the present invention relates to the detection and analysis of the non-human sialic acid, N-glycolylneuraminic acid (Neu5Gc) in bio-logical materials, such as food and clinical specimens. Such detection and analysis is facilitated by the use of Neu5Gc specific antibodies. The present invention also relates to the detection of anti Neu5Gc antibodies in clinical samples, as well as the production of anti-Neu5Gc specific antibodies.
    Type: Grant
    Filed: July 14, 2004
    Date of Patent: March 23, 2010
    Assignee: The Regents of the University of California
    Inventors: Ajit Varki, Pam Tangvoranuntakul, Nissi Varki, Elaine Muchmore, Pascal Gagneux, Sandra Diaz