Patents by Inventor Nitin Ashok Shimpi

Nitin Ashok Shimpi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amorphous trisodium sacubitril valsartan and a process for the preparation thereof
    Patent number: 10562866
    Abstract: The amorphous form of trisodium sacubitril valsartan and methods for the preparation thereof are disclosed herein.
    Type: Grant
    Filed: February 6, 2016
    Date of Patent: February 18, 2020
    Assignee: Mylan Laboratories Limited
    Inventors: Vellanki Sivaram Prasad, Arabinda Sahu, Siva Koteswara Rao Prathi, Lakshmana Rao Ampolu, Ramakoteswara Rao Jetti, Aggi Ramireddy Bommareddy, Neelima Bhagavatula, Nitin Ashok Shimpi
  • AMORPHOUS TRISODIUM SACUBITRIL VALSARTAN AND A PROCESS FOR THE PREPARATION THEREOF
    Publication number: 20180273493
    Abstract: The amorphous form of trisodium sacubitril valsartan and methods for the preparation thereof are disclosed herein.
    Type: Application
    Filed: February 6, 2016
    Publication date: September 27, 2018
    Applicant: Mylan Laboratories Limited
    Inventors: Vellanki Sivaram Prasad, Arabinda Sahu, Siva Koteswara Rao Prathi, Lakshmana Rao Ampolu, Ramakoteswara Rao Jetti, Aggi Ramireddy Bommareddy, Neelima Bhagavatula, Nitin Ashok Shimpi, Manisha Singh
  • Process for the preparation of (3R, 3aS, 6aR)-hexahydrofuro [2, 3-b] furan-3-ol
    Patent number: 8841467
    Abstract: The present invention relates to a novel process for the preparation of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol of formula I by reacting a compound of formula VII with the compound of formula R2-OH in the presence of haloginating agent to obtain a compound of formula VI and treating a compound of formula VI with dehaloginating agent to obtain a compound of formula V by reducing a compound of formula V, followed by cylization to obtain compound of formula IV and separating the enantiomer and diastereomers from compound of formula IV to yield a compound of formula I. Compound of formula I is useful as an intermediate in the preparation of protease inhibitors, in particular broad spectrum HIV protease inhibitors, the present invention also relates to process for the preparation of Darunavir from (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol.
    Type: Grant
    Filed: July 14, 2011
    Date of Patent: September 23, 2014
    Assignee: Mylan Laboratories Limited
    Inventors: Siva Rama Prasad Vellenki, Arabinda Sahu, Nitin Ashok Shimpi, Anil Ponnuru, Satish Babu Kothari
  • PROCESS FOR THE PREPARATION OF (3R, 3AS, 6AR)-HEXAHYDROFURO [2, 3- B] FURAN-3-OL
    Publication number: 20130244297
    Abstract: The present invention relates to a novel process for the preparation of (3R, 3aS, 6aR)-hexahydrofuro[2, 3-b]furan-3-ol of formula I by reacting a compound of formula VII with the compound of formula R2-OH in the presence of haloginating agent to obtain a compound of formula VI and treating a compound of formula VI with dehaloginating agent to obtain a compound of formula V by reducing a compound of formula V, followed by cylization to obtain compound of formula IV and separating the enantiomer and diastereomers from compound of formula IV to yield a compound of formula I. Compound of formula I is useful as an intermediate in the preparation of protease inhibitors, in particular broad spectrum HIV protease inhibitors, the present invention also relates to process for the preparation of Darunavir from (3R, 3aS, 6aR)-hexahydrofuro[2, 3-b]furan-3-ol.
    Type: Application
    Filed: July 14, 2011
    Publication date: September 19, 2013
    Applicant: Mylan Laboratories Ltd.
    Inventors: Siva Rama Prasad Vellenki, Arabinda Sahu, Nitin Ashok Shimpi, Anil Ponnuru, Satish Babu Kothari
  • MONTELUKAST BENZHYDRYL PIPERAZINE SALTS AND PROCESS FOR PREPARATION THEREOF
    Publication number: 20100292251
    Abstract: The invention relates to Benzhydryl piperazine salts of [R-(E)]-1-[[[1-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid represented by the formula (III). Furthermore, the invention relates to the use of Benzhydryl piperazine salts of [R-(E)]-1-[[[1-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid represented by the formula (III) for the preparation of substantially pure [R-(E)]-1-[[[1-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropane acetic acid or its alkali salts and pharmaceutical composition comprising the same.
    Type: Application
    Filed: January 5, 2009
    Publication date: November 18, 2010
    Applicant: Torrent Pharmaceuticals Limited
    Inventors: Nitin Ashok Shimpi, Mahendra Gordhanbhai Lakkad, Sunil Sadanand Nadkarni, Srinivasa Rao A.v.v.