Patents by Inventor Nitin Shetty

Nitin Shetty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted piperidino phenyloxazolidinones having antimicrobial activity with improved in vivo efficacy
    Patent number: 8729269
    Abstract: The present invention provides agents having antimicrobial activity for preventing and treating infectious diseases. Thus, the present invention provides novel substituted piperidino phenyloxazolidinone derivatives, processes for making compounds as well as antimicrobial compositions containing said derivatives as active ingredients and methods of treating bacterial infections with the said derivatives.
    Type: Grant
    Filed: February 12, 2010
    Date of Patent: May 20, 2014
    Assignee: Wockhardt Limited
    Inventors: Prasad Keshav Deshpande, Milind Dattatraya Sindkhedkar, Mahesh Shriram Phansalkar, Ravindra Dattatraya Yeole, Shrikant Vinayak Gupte, Yati Chugh, Nitin Shetty, Sachin Subhash Bhagwat, Milind Chintaman Shukla, Noel John De Souza, Mahesh Vithalbhai Patel
  • SUBSTITUTED PIPERIDINO PHENYLOXAZOLIDINONES HAVING ANTIMICROBIAL ACTIVITY WITH IMPROVED IN VIVO EFFICACY
    Publication number: 20100144735
    Abstract: The present invention provides agents having antimicrobial activity for preventing and treating infectious diseases. Thus, the present invention provides novel substituted piperidino phenyloxazolidinone derivatives, processes for making compounds as well as antimicrobial compositions containing said derivatives as active ingredients and methods of treating bacterial infections with the said derivatives.
    Type: Application
    Filed: February 12, 2010
    Publication date: June 10, 2010
    Inventors: Prasad Keshav Deshpande, Milind Dattatraya Sindkhedkar, Mahesh Shriram Phansalkar, Ravindra Dattatraya Yeole, Shrikant Vinayak Gupte, Yati Chugil, Nitin Shetty, Sachin Subhash Bhagwat, Milind Chintaman Shukla, Noel John De Souza, Mahesh Vithalbhai Patel
  • Substituted piperidino phenyloxazolidinones having antimicrobial activity with improved in vivo efficacy
    Patent number: 7687627
    Abstract: The present invention provides agents having antimicrobial activity for preventing and treating infectious diseases. Thus, the present invention provides novel substituted piperidino phenyloxazolidinone derivatives, processes for making compounds as well as antimicrobial compositions containing said derivatives as active ingredients and methods of treating bacterial infections with the said derivatives.
    Type: Grant
    Filed: September 7, 2004
    Date of Patent: March 30, 2010
    Assignee: Wockhardt Limited
    Inventors: Prasad Keshav Deshpande, Milind Dattatraya Sindkhedkar, Mahesh Shriram Phansalkar, Ravindra Dattatraya Yeole, Shrikant Vinayak Gupte, Yati Chugh, Nitin Shetty, Sachin Subhash Bhagwat, Milind Chintaman Shukla, Noel John De Souza, Mahesh Vithalbhai Patel
  • Antibacterial cyano-(substituted)-methylenepiperidinophenyl oxazolidinones targeting multiple ribonucleoprotein sites
    Patent number: 7405228
    Abstract: The present invention provides agents having high antimicrobial activity for preventing and treating infectious diseases. Thus, the present invention provides novel cyano-(substituted)-methylenepiperidinophenyl oxazolidinone derivatives, processes for making the compounds, as well as antimicrobial compositions containing said derivatives as active ingredients and methods of treating bacterial infections with the said derivatives.
    Type: Grant
    Filed: July 10, 2003
    Date of Patent: July 29, 2008
    Assignee: Wockhardt Limited
    Inventors: Mahesh V Patel, Prasad K Deshpande, Milind D Sindkhedkar, Shrikant V Gupte, Yati Chugh, Nitin Shetty, Milind C Shukla, Ravindra D Yeole, Noel J De Souza
  • Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment
    Publication number: 20080108646
    Abstract: The present invention relates to optically pure S-(?)-benzoquinolizine carboxylic acids, their derivatives, salts, pseudopolymorphs, polymorphs and hydrates thereof, substantially free of their R-(+)-isomers, to processes for preparation of the optically pure S-(?)-benzoquinolizine carboxylic acids, their derivatives, salts, pseudopolymorphs, polymorphs and hydrates thereof substantially free of their R-(+)-isomers, and to pharmaceutical compositions comprising the S(?)-benzoquinolizine carboxylic acids, their derivatives, salts, pseudopolymorphs, polymorphs and hydrates thereof.
    Type: Application
    Filed: July 23, 2007
    Publication date: May 8, 2008
    Inventors: Mahesh Patel, Shivkumar Agarwal, Sreenivas Kandepu, Nitin Shetty, Dilip Upadhyay, Nishith Chaturvedi, Abraham Thomas, Noel De Souza, Habil Khorakiwala
  • Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment
    Patent number: 7247642
    Abstract: The present invention relates to optically pure S-(?)-benzoquinolizine carboxylic acids, their derivatives, salts, pseudopolymorphs, polymorphs and hydrates thereof, substantially free of their R-(+)-isomers, to processes for preparation of the optically pure S-(?)-benzoquinolizine carboxylic acids, their derivatives, salts, pseudopolymorphs, polymorphs and hydrates thereof substantially free of their R-(+)-isomers, and to pharmaceutical compositions comprising the S(?)-benzoquinolizine carboxylic acids, their derivatives, salts, pseudopolymorphs, polymorphs and hydrates thereof.
    Type: Grant
    Filed: May 8, 2000
    Date of Patent: July 24, 2007
    Assignee: Wockhardt Limited
    Inventors: Mahesh Vithalbhai Patel, Shivkumar Agarwal, Sreenivas Kandepu, Nitin Shetty, Dilip Jatashankar Upadhyay, Nishith Chandra Chaturvedi, Abraham Thomas, Noel John De Souza, Habil Fakhruddin Khorakiwala
  • Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
    Patent number: 6964966
    Abstract: This invention relates to new generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, to their optical isomers, diastereomers or enantiomers, as well as pharmaceutically acceptable salts, hydrates, prodrugs, polymorphs and pseudopolymorphs thereof, to their preparation, to their compositions and to their use.
    Type: Grant
    Filed: April 23, 2002
    Date of Patent: November 15, 2005
    Assignee: Wockhardt Limited
    Inventors: Noel John De Souza, Mahesh Vithalbhai Patel, Prasad Keshav Deshpande, Shiv Kumar Agarwal, Shrikant V. Gupte, Dilip J. Upadhyay, Satish B. Bhawsar, Rupinder K. Beri, Kandepu Sreenivas, Sheela Chandrasekharan Nair, Milind Chintaman Shukla, Yati Chugh, Nitin Shetty, Ravindra D. Yeole, M. Madhav Reddy
  • Substituted piperidino phenyloxazolidinones having antimicrobial activity with improved in vivo efficacy
    Publication number: 20050143421
    Abstract: The present invention provides agents having antimicrobial activity for preventing and treating infectious diseases. Thus, the present invention provides novel substituted piperidino phenyloxazolidinone derivatives, processes for making compounds as well as antimicrobial compositions containing said derivatives as active ingredients and methods of treating bacterial infections with the said derivatives.
    Type: Application
    Filed: September 7, 2004
    Publication date: June 30, 2005
    Inventors: Prasad Deshpande, Milind Sindkhedkar, Mahesh Phansalkar, Ravindra Yeole, Shrikant Gupte, Yati Chugh, Nitin Shetty, Sachin Bhagwat, Milind Shukla, Noel De Souza, Mahesh Patel
  • Antimicrobial oxazolifinones with improved pharmacokinetic profile and safety advantages
    Publication number: 20040235900
    Abstract: The present invention provides agents having high antimicrobial activity for preventing and treating infectious diseases. Thus, the present invention provides novel cyanoalkylpiperidinophenyl oxazolidinone derivatives having antimicrobial activity, favourable pharmacokinetic and safety profiles, processes for making the compounds, as well as antimicrobial compositions containing said derivatives as active ingredients and methods of treating microbial infections with the said derivatives.
    Type: Application
    Filed: October 23, 2003
    Publication date: November 25, 2004
    Inventors: Yati Chugh, Nitin Shetty, Prasad K Deshpande, Milind D Sindkhedkar, Mohammad A Jafri, Ravinda D Yeole, Milind C Shukla, Shirikant V Gupte, Mahesh V Patel, Noel J De Souza
  • Compositions of benzoquinolizine carboxylic acid antibiotic drugs
    Publication number: 20040176321
    Abstract: The present invention relates to a pharmaceutical composition in aqueous solution form useful for parenteral application to a subject for treatment or prevention of infective disease. In particular the present invention relates to such a composition having as an active agent S-(−)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid, S-(−)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid 0.2 hydrate or S-(−)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid arginine salt or a benzoquinolizine-2-carboxylic acid antibiotic drug. The field of the invention also includes processes for the preparation of such a composition, the use of such a composition in preparation of a medicament, and to the therapeutic or prophylactic use of such a composition.
    Type: Application
    Filed: December 31, 2003
    Publication date: September 9, 2004
    Applicant: WOCKHARDT LIMITED
    Inventors: Dilip G. Saoji, Rajendra N. Nagori, Ravindra D. Yeole, Nitin Shetty, Milind C. Shukla, Noel J. de Souza
  • Chiral fluoroquinolone arginine salt forms
    Patent number: 6753333
    Abstract: The invention relates to the new arginine salt forms of S-(−)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid, a process for their preparation and pharmaceutical formulations which comprise those arginine salt forms as the active ingredient for its use in treating antimicrobial infections.
    Type: Grant
    Filed: November 22, 2002
    Date of Patent: June 22, 2004
    Assignee: Wockhardt Limited
    Inventors: Noel J. De Souza, Shivkumar Agarwal, Mahesh V. Patel, Satish B. Bhawsar, Rupinder K. Beri, Ravindra D. Yeole, Nitin Shetty
  • Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment
    Patent number: 6750224
    Abstract: The present invention relates to optically pure S-(−)-benzoquinolizine carboxylic acids, their derivatives, salts, pseudopolymorphs, polymorphs and hydrates thereof, substantially free of their R-(+)-isomers, to processes for preparation of the optically pure S-(−)-benzoquinolizine carboxylic acids, their derivatives, salts, pseudopolymorphs, polymorphs and hydrates thereof substantially free of their R-(+)-isomers, and to pharmaceutical compositions comprising the S(−)-benzoquinolizine carboxylic acids, their derivatives, salts, pseudopolymorphs, polymorphs and hydrates thereof.
    Type: Grant
    Filed: August 17, 2000
    Date of Patent: June 15, 2004
    Assignee: Wockhardt Limited
    Inventors: Mahesh Vithalbhai Patel, Shivkumar Agarwal, Sreenivas Kandepu, Nitin Shetty, Dilip Upadhyay, Nishith Chaturvedi, Abraham Thomas, Noel John De Souza, Habil Fakhruddin Khorakiwala
  • Antibacterial cyano-(substituted)-methylenepiperidinophenyl oxazolidinones targeting multiple ribonucleoprotein sites
    Publication number: 20040063954
    Abstract: The present invention provides agents having high antimicrobial activity for preventing and treating infectious diseases. Thus, the present invention provides novel cyano-(substituted)-methylenepiperidinophenyl oxazolidinone derivatives, processes for making the compounds, as well as antimicrobial compositions containing said derivatives as active ingredients and methods of treating bacterial infections with the said derivatives.
    Type: Application
    Filed: July 10, 2003
    Publication date: April 1, 2004
    Applicant: WOCKHARDT LIMITED
    Inventors: Mahesh V. Patel, Prasad K. Deshpande, Milind D. Sindkhedkar, Shrikant V. Gupte, Yati Chugh, Nitin Shetty, Milind C. Shukla, Ravindra D. Yeole, Noel J. De Souza
  • Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment
    Publication number: 20030207908
    Abstract: The present invention relates to optically pure S-(−)-benzoquinolizlne carboxylic acids, their derivatives, salts, pseudopolymorphs, polymorphs and hydrates thereof, substantially free of their R-(+)-isomers, to processes for preparation of the optically pure S-(−)-benzoquinoluzie carboylic acids, their derivatives, salts, pseudopolymorphs, polymorphs and hydrates thereof substantlly free of their R-(+)-isomers, and to pharmaceutical compositions comprising the S(+)-benzoquinolizie carboxylic acids, their derivatives, salts, pseudopolymorphs, polymorphs and hydrates thereof.
    Type: Application
    Filed: May 8, 2000
    Publication date: November 6, 2003
    Inventors: Mahesh Vithalbhai Patel, Shivkumar Agarwal, Sreenivas Kandepu, Nitin Shetty, Dilip Jatashankar Upadhyay, Nishith Chandra Chaturvedi, Abraham Thomas, Noel John De Souza, Habil Fakhruddin Khorakiwala
  • Chiral fluoroquinolone arginine salt forms
    Publication number: 20030144517
    Abstract: The invention relates to the new arginine salt forms of S-(−)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid, a process for their preparation and pharmaceutical formulations which comprise those arginine salt forms as the active ingredient for its use in treating antimicrobial infections.
    Type: Application
    Filed: November 22, 2002
    Publication date: July 31, 2003
    Applicant: WOCKHARDT LIMITED
    Inventors: Noel J. De Souza, Shivkumar Agarwal, Mahesh V. Patel, Satish B. Bhawsar, Rupinder K. Beri, Ravindra D. Yeole, Nitin Shetty
  • Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-Quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
    Publication number: 20030096812
    Abstract: This invention relates to new generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, to their optical isomers, diastereomers or enantiomers, as well as pharmaceutically acceptable salts, hydrates, prodrugs, polymorphs and pseudopolymorphs thereof, to their preparation, to their compositions and to their use.
    Type: Application
    Filed: April 23, 2002
    Publication date: May 22, 2003
    Applicant: WOCKHARDT LIMITED
    Inventors: Noel John De Souza, Mahesh Vithalbhai Patel, Prasad Keshav Deshpande, Shiv Kumar Agarwal, Shrikant V. Gupte, Dilip J. Upadhyay, Satish B. Bhawsar, Rupinder K. Beri, Kandepu Sreenivas, Sheela Chandrasekharan Nair, Milind Chintaman Shukla, Yati Chugh, Nitin Shetty, Ravindra D. Yeole, M. Madhav Reddy
  • Novel in-situ forming controlled release microcarrier delivery system
    Publication number: 20030049320
    Abstract: A ready-to use, stable, gelled polymer droplet-in-oil dispersion is described which helps in in-situ formation of a multitude of small solid, semisolid, or gelled microcarriers. The dispersion is placed into a body in a semisolid form and cures to form the delivery system in-situ. The process for making such a dispersion comprises the steps of (i) dissolving a polymer in a biocompatible solvent at an elevated temperature to form a polymer solution, (ii) preparing a second oil phase solution of a biocompatible oil and a biocompatible emulsifier at an elevated temperature, (iii) mixing the polymer solution with the oil phase solution at an elevated temperature and subsequently cooling to refrigeration temperature. Placing the gelled dispersion within a body produces the microcarrier delivery system in-situ.
    Type: Application
    Filed: December 12, 2001
    Publication date: March 13, 2003
    Applicant: WOCKHARDT LIMITED
    Inventors: Harshal P. Bhagwatwar, Varada R. Bapat, Mahesh B. Paithankar, Bhushan S. Yeola, Arun S. Gosavi, Manoj A. Bagool, Nitin Shetty, Milind C. Shukla, Noel J. De Souza, Nishith C. Chaturvedi, Suresh Beri
  • Chiral fluoroquinolone arginine salt forms
    Patent number: 6514986
    Abstract: The invention relates to the new arginine salt forms of S-(−)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid, a process for their preparation and pharmaceutical formulations which comprise those arginine salt forms as the active ingredient for its use in treating antimicrobial infections.
    Type: Grant
    Filed: March 9, 2001
    Date of Patent: February 4, 2003
    Assignee: Wockhardt Limited
    Inventors: Noel J. de Souza, Shivkumar Agarwal, Mahesh V. Patel, Satish B. Bhawsar, Rupinder K. Beri, Ravindra D. Yeole, Nitin Shetty
  • Chiral fluoroquinolone arginine salt forms
    Publication number: 20020061908
    Abstract: The invention relates to the new arginine salt forms of S-(−)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid, a process for their preparation and pharmaceutical formulations which comprise those arginine salt forms as the active ingredient for its use in treating antimicrobial infections.
    Type: Application
    Filed: March 9, 2001
    Publication date: May 23, 2002
    Applicant: WOCKHARDT LTD
    Inventors: Noel J. de Souza, Shivkumar Agarwal, Mahesh V. Patel, Satish B. Bhawsar, Rupinder K. Beri, Ravindra D. Yeole, Nitin Shetty, Habil F. Khorakiwala