Patents by Inventor Nitish Thakor

Nitish Thakor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11867892
    Abstract: An embodiment in accordance with the present invention provides a miniature microscope capable of performing in vivo, real-time imaging of multiple organ sites in awake and behaving animals (e.g. rodents). A microscope according to the present invention includes multiple optical contrast mechanisms (i.e. contrast arising from neural, hemodynamic and other physiological components). Exemplary contrast mechanisms include, but are not limited to fluorescence, hemoglobin level, deoxyhemoglobin level, and blood flow. The microscope is fully adaptable to in vitro and ex vivo imaging, can be customized to concurrently image at variable magnifications, conduct optogenetic/electrical/chemical stimulations, drug delivery, microdialysis, accompanied by electrical signal recording, wireless image transmission and charging.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: January 9, 2024
    Assignee: The Johns Hopkins University
    Inventors: Arvind Pathak, Nitish Thakor, Janaka Senarathna, Hang Yu
  • Publication number: 20200225457
    Abstract: An embodiment in accordance with the present invention provides a miniature microscope capable of performing in vivo, real-time imaging of multiple organ sites in awake and behaving animals (e.g. rodents). A microscope according to the p resent invention includes multiple optical contrast mechanisms (i.e. contrast arising from neural, hemodynamic and other physiological components). Exemplary contrast mechanisms include, but are not limited to fluorescence, hemoglobin level, deoxyhemoglobin level, and blood flow. The microscope is fully adaptable to in vitro and ex vivo imaging, can be customized to concurrently image at variable magnifications, conduct optogenetic/electrical/chemical stimulations, drug delivery, micro-dialysis, accompanied by electrical signal recording, wireless image transmission and charging.
    Type: Application
    Filed: July 6, 2018
    Publication date: July 16, 2020
    Inventors: Arvind PATHAK, Nitish THAKOR, Janaka SENARATHNA, Hang YU
  • Patent number: 10092190
    Abstract: A system for multimodal laser speckle imaging may include a first light source positioned to emit laser light toward a target, a second light source positioned to emit light toward the target, a camera positioned to receive light scattered from the target, and a processor.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: October 9, 2018
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Abhishek Rege, Nitish Thakor, Kartikeya Murari, Nan Li
  • Publication number: 20160113504
    Abstract: A system for multimodal laser speckle imaging may include a first light source positioned to emit laser light toward a target, a second light source positioned to emit light toward the target, a camera positioned to receive light scattered from the target, and a processor.
    Type: Application
    Filed: October 9, 2015
    Publication date: April 28, 2016
    Inventors: Abhishek REGE, Nitish THAKOR, Kartikeya MURARI, Nan Li
  • Patent number: 9155480
    Abstract: A system for multimodal laser speckle imaging may include a first light source positioned to emit laser light toward a target, a second light source positioned to emit light toward the target, a camera positioned to receive light scattered from the target, and a processor.
    Type: Grant
    Filed: September 7, 2010
    Date of Patent: October 13, 2015
    Assignee: The Johns Hopkins University
    Inventors: Nitish Thakor, Abhishek Rege, Nan Li, Kartikeya Murari
  • Publication number: 20120162438
    Abstract: A system for multimodal laser speckle imaging may include a first light source positioned to emit laser light toward a target, a second light source positioned to emit light toward the target, a camera positioned to receive light scattered from the target, and a processor.
    Type: Application
    Filed: September 7, 2010
    Publication date: June 28, 2012
    Applicant: The John Hopkins University
    Inventors: Nitish Thakor, Abhishek Rege, Nan Li, Kartikeya Murari
  • Publication number: 20070244403
    Abstract: One embodiment enables detection of MI/I and emerging infarction in an implantable system. A plurality of devices may be used to gather and interpret data from within the heart, from the heart surface, and/or from the thoracic cavity. The apparatus may further alert the patient and/or communicate the condition to an external device or medical caregiver. Additionally, the implanted apparatus may initiate therapy of MI/I and emerging infarction.
    Type: Application
    Filed: June 19, 2007
    Publication date: October 18, 2007
    Inventors: Ananth Natarajan, Nitish Thakor
  • Publication number: 20070129639
    Abstract: One embodiment relates to a method of monitoring the heart of a subject for evidence of at least one of myocardial ischemia and infarction (MI/I). The method includes sensing an intra-cardiac electrical signal from at least one lead positioned in a subject. The method also includes detecting MI/I using at least one of the QRS portion of the intra-cardiac electrical signal and the ST portion of the intra-cardiac electrical signal. The detecting MI/I includes using an integer coefficient filter to extract MI/I information from the intra-cardiac electrical signal.
    Type: Application
    Filed: January 10, 2005
    Publication date: June 7, 2007
    Inventors: Hongxuan Zhang, Nitish Thakor, Jeffrey Wallace, Ananth Natarajan
  • Publication number: 20060106283
    Abstract: Embodiments include devices and methods. One embodiment includes a method for imaging an endometrial cavity, including acquiring a plurality of images using an imaging system. A first part of the imaging system is positioned within the endometrial cavity. At least portions of two or more of the images are combined into a representation of at least a portion of the endometrial cavity. The combining at least portions of two of the images may include determining any motion of the first part of the imaging system, between the two or more of the images. Other embodiments are described and claimed.
    Type: Application
    Filed: October 18, 2005
    Publication date: May 18, 2006
    Inventors: Jeffrey Wallace, Ananth Natarajan, Santosh Venkatesha, Keith Peacock, Nitish Thakor
  • Publication number: 20050267569
    Abstract: Devices and methods are described. One apparatus includes a stent including a sensor coupled thereto, the sensor including a material that oscillates when subjected to an applied magnetic field. The material may include at least one material selected from magnetoelastic materials and magnetorestrictive materials. The apparatus may further include a system adapted to monitor the sensor, the system including a generator adapted to apply a magnetic field that generates physical oscillations in the sensor, and a monitor adapted to detect magnetic fluctuation generated from the physical oscillations in the sensor. Other embodiments are described and claimed.
    Type: Application
    Filed: March 25, 2005
    Publication date: December 1, 2005
    Inventors: Gary Barrett, Jeffrey Wallace, Nitish Thakor, Ananth Natarajan