Patents by Inventor Nitnara Viroonchatapan

Nitnara Viroonchatapan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for biodegradable polymer-peptide mediated transfection
    Patent number: 7446099
    Abstract: Complexes are disclosed which are a combination of a polynucleotide and a biodegradable polyacetal-peptide. The disclosed complexes are useful for cell transfection.
    Type: Grant
    Filed: February 27, 2004
    Date of Patent: November 4, 2008
    Assignee: Nitto Denko Corporation
    Inventors: Sang Van, Nitnara Viroonchatapan, Shouping Ji, Kenji Matsumoto, Lei Yu
  • Acid-sensitive polyacetals and methods
    Patent number: 7048925
    Abstract: Polyacetals comprising a recurring units represented by a formula selected from the group consisting of formula (I) and (II): wherein A comprises at least one acetal group; B is selected from the group consisting of —CH—, —CH(CH3)—, CH2CH—, —CH2C(CH3)—, —CH(CH3)CH—, and —CHCH(CH3)CH(CH3)—; Z is selected from the group consisting of C(O)OR1, C(O)SR1, C(O)NR1R2, and VU; V is a linker group; U is selected from the group consisting of poly(ethyleneimine), poly(propyleneimine), poly(lysine), PAMAM dendrimer, octaamine dendrimer, hexadecaamine dendrimer, enhancer, and targeting receptor; R1 and R2 are each individually selected from the group consisting of hydrogen, C1 to C10 alkyl, and C6 to C10 aryl; D is a linkage selected from the group consisting of carboxylic amide, carboxylic ester, urea, and urethane; and G is selected from the group consisting of C4 to C20 alkyl, C6-C10 aryl, and —(OCH2CH2)n—, where n is in the range of 1 to about 250, are useful in nucleic acid delivery applications.
    Type: Grant
    Filed: August 28, 2003
    Date of Patent: May 23, 2006
    Assignee: Nitto Denko Corporation
    Inventors: Sang Van, Nitnara Viroonchatapan, Shouping Ji, Lei Yu
  • Compositions and methods for biodegradable polymer-peptide mediated transfection
    Publication number: 20050191746
    Abstract: Complexes are disclosed which are a combination of a polynucleotide and a biodegradable polyacetal-peptide. The disclosed complexes are useful for cell transfection.
    Type: Application
    Filed: February 27, 2004
    Publication date: September 1, 2005
    Inventors: Sang Van, Nitnara Viroonchatapan, Shouping Ji, Kenji Matsumoto, Lei Yu
  • ACID-SENSITIVE POLYACETALS AND METHODS
    Publication number: 20050049387
    Abstract: Polyacetals comprising a recurring units represented by a formula selected from the group consisting of formula (I) and (II): wherein A comprises at least one acetal group; B is selected from the group consisting of —CH—, —CH(CH3)—, CH2CH—, —CH2C(CH3)—, —CH(CH3)CH—, and —CHCH(CH3)CH(CH3)—; Z is selected from the group consisting of C(O)OR1, C(O)SR1, C(O)NR1R2, and VU; V is a linker group; U is selected from the group consisting of poly(ethyleneimine), poly(propyleneimine), poly(lysine), PAMAM dendrimer, octaamine dendrimer, hexadecaamine dendrimer, enhancer, and targeting receptor; R1 and R2 are each individually selected from the group consisting of hydrogen, C1 to C10 alkyl, and C6 to C10 aryl; D is a linkage selected from the group consisting of carboxylic amide, carboxylic ester, urea, and urethane; and G is selected from the group consisting of C4 to C20 alkyl, C6-C10 aryl, and —(OCH2CH2)n—, where n is in the range of 1 to about 250, are useful in nucleic acid delivery applications.
    Type: Application
    Filed: August 28, 2003
    Publication date: March 3, 2005
    Inventors: Sang Van, Nitnara Viroonchatapan, Shouping Ji, Lei Yu