Abstract: An electrode assembly for delivering tumor treating fields to a subject's body, the electrode assembly apparatus including a layer of conductive anisotropic material, an electrode element and a cover. The electrode assembly is provided in different shapes, such as an asymmetric oval, including ovaloid, ovoid and ovate shapes or stretched asymmetric oval, ovaloid, ovoid, or ovate shapes, as well as a pear shape and a rounded arrowhead shape. These shapes can be provided in different sizes to allow the electrode assembly to be attached or secured to a subject or patient's body, especially when the site may be nonplanar, or otherwise contoured, resulting in a more comfortable experience, or even a more favorable clinical outcome.

Abstract: Alternating electric fields (e.g., Tumor Treating Fields or TTFields) can be applied to a subject's body using an apparatus (e.g., a transducer array) that includes at least one metal pad disposed on a substrate and a plurality of temperature sensors (e.g., thermistors). The temperature sensors are disposed on the substrate at positions that are outside a first convex hull that encloses the at least one metal pad (e.g., at the edges of the apparatus). A layer of graphite is disposed in front of the metal pads and the temperature sensors and is in thermal contact with both the metal pads and the temperature sensors. Positioning the thermistors outside the first convex hull (e.g., at the edges of the apparatus) can help prevent overheating in situations where the edges of the apparatus tend to be the hottest portions of the apparatus.

Abstract: A transducer apparatus for delivering tumor treating fields to a subject's body, the transducer apparatus including: an array of electrodes, the array configured to be positioned over the subject's body with a front face of the array facing the subject's body, the array comprising electrode elements positioned in existing electrode positions arranged around a centroid of the array; an anisotropic material layer electrically coupled to the array of electrodes and located on a front side of the front face of the array; and at least one void space in the array of electrodes capable of enclosing an areal footprint equivalent to at least a portion of an areal footprint of at least one existing electrode position, and superimposable on at least a portion of at least one existing electrode position by rotation of the array around the centroid.

Abstract: A transducer apparatus for delivering tumor treating fields to a subject's body, the transducer apparatus comprising: a substrate; and an array of at least one electrode disposed on the substrate, the array configured to be positioned over the subject's body with a face of the array facing the subject's body; wherein the transducer apparatus is substantially non-planar, wherein the transducer apparatus is substantially shaped as a truncated elliptical paraboloid, truncated oblique cone, or truncated cone, and a substantially circular opening is formed by an opening at a truncated portion of the truncated elliptical paraboloid, truncated oblique cone, or truncated cone.

Abstract: A transducer apparatus for delivering tumor treating fields to a subject's body, the transducer apparatus comprising: a substrate; an array of at least one electrode disposed on the substrate, the array configured to be positioned over the subject's body with a face of the array facing the subject's body, the array capable of delivering tumor treating fields to a subject's body; and a layer of anisotropic material positioned on a skin-facing side of the array; wherein, when viewed from a direction perpendicular to the face of the array, the layer of anisotropic material comprises an interior slit extending substantially along a longitudinal direction of the layer of anisotropic material, the interior slit is surrounded by anisotropic material, and no electrodes are in the interior slit.

Abstract: A transducer apparatus for delivering tumor treating fields to a subject's body, the transducer apparatus including: an array of electrodes, the array configured to be positioned over the subject's body with a front face of the array facing the subject's body, the array including electrode elements; and an anisotropic material layer electrically coupled to the array of electrodes and located on a front side of the front face of the array, the anisotropic material layer including a front face and a back face, the back face facing the array of electrodes. The anisotropic material layer further includes a hole passing through the front face and the back face of the anisotropic material layer, wherein the electrode elements are positioned around the hole of the anisotropic material layer.

Abstract: A transducer apparatus for delivering tumor treating fields to a subject’s body, the transducer apparatus including: an array of electrode elements, the array configured to be positioned over the subject’s body with a face of the array facing the subject’s body; wherein, when viewed from a direction perpendicular to the face of the array, an outer perimeter of the array substantially tracing the electrode elements has a shape including: at least one convex edge portion protruding away from a centroid of the array; and at least one concave edge portion recessed toward the centroid of the array.

Abstract: A transducer apparatus for delivering tumor treating fields to a subject's body, the transducer apparatus including: a plurality of electrode elements; wherein the plurality of electrode elements comprises a first electrode element and a second electrode element, wherein the first electrode element and the second electrode element are substantially located in a plane of the transducer apparatus; and when viewed from a direction perpendicular to the plane, the first electrode element and the second electrode element have edges located adjacent each other without any other electrodes between them, wherein the edges of the first electrode element and the second electrode element extend parallel to each other along their length.

Abstract: A transducer array for use in tumor-treating fields (TTFields) therapy is particularly suited for use in treating abdominal or thoracic cancers. The transducer array has features that increase its flexibility and adhesion to the patient's skin, including a branching configuration and a correspondingly branching top covering adhesive-backed layer. Additionally, a skin-level adhesive layer is provided beneath the flex circuit to which the electrode elements are attached, to help ensure thorough, lasting adhesion of the transducer array to the patient's skin over the course of treatment.

Abstract: A transducer array for use in tumor-treating fields (TTFields) therapy is particularly suited for use in treating abdominal or thoracic cancers. The transducer array has features that increase its flexibility and adhesion to the patient's skin, including a branching configuration and a correspondingly branching top covering adhesive-backed layer. Additionally, a skin-level adhesive layer is provided beneath the flex circuit to which the electrode elements are attached, to help ensure thorough, lasting adhesion of the transducer array to the patient's skin over the course of treatment.