Patents by Inventor Noah Basri

Noah Basri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC SPLICE-SWITCHING OLIGONUCLEOTIDES FOR CANCER
    Publication number: 20240150764
    Abstract: The present disclosure provides for splice-switching oligonucleotides (SSOs) targeted to a nucleic acid encoding a transposable element (TE)-driven isoform of LIN28B, such as AluJb-LIN28B. The SSOs may be targeted to an exon-intron or intron-exon junction to inhibit splicing and expression of the TE-driven isoform of LIN28B. Methods of treating cancer, particularly cancers expressing AluJb-LIN28B, comprising administering the SSOs are also provided.
    Type: Application
    Filed: November 7, 2023
    Publication date: May 9, 2024
    Applicant: Washington University
    Inventors: Noah Basri, Ting Wang