Patents by Inventor Noah Berkowitz

Noah Berkowitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reagents and methods for detecting a polymorphic protein
    Patent number: 9518993
    Abstract: The present invention provides antibodies that differentially react with allelic variants of a polymorphic protein, methods of identifying same, an antigen binding fragment comprised therein, proteins, cells, viral particles, compositions, and kits comprising same. The invention also provides methods for determining a haptoglobin type of a subject and methods for testing a subject for susceptibility to diabetic complications.
    Type: Grant
    Filed: November 3, 2014
    Date of Patent: December 13, 2016
    Assignee: RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES
    Inventors: Jacob Victor, Noah Berkowitz, Andrew Levy
  • REAGENTS AND METHODS FOR DETECTING A POLYMORPHIC PROTEIN
    Publication number: 20150056640
    Abstract: The present invention provides antibodies that differentially react with allelic variants of a polymorphic protein, methods of identifying same, an antigen binding fragment comprised therein, proteins, cells, viral particles, compositions, and kits comprising same. The invention also provides methods for determining a haptoglobin type of a subject and methods for testing a subject for susceptibility to diabetic complications.
    Type: Application
    Filed: November 3, 2014
    Publication date: February 26, 2015
    Inventors: Jacob VICTOR, Noah Berkowitz, Andrew Levy
  • Reagents and methods for detecting a polymorphic protein
    Patent number: 8901282
    Abstract: The present invention provides antibodies that differentially react with allelic variants of a polymorphic protein, methods of identifying same, an antigen binding fragment comprised therein, proteins, cells, viral particles, compositions, and kits comprising same. The invention also provides methods for determining a haptoglobin type of a subject and methods for testing a subject for susceptibility to diabetic complications.
    Type: Grant
    Filed: June 11, 2009
    Date of Patent: December 2, 2014
    Assignee: Rappaport Family Institute for Research in the Medical Sciences
    Inventors: Jacob Victor, Noah Berkowitz, Andrew Levy
  • REAGENTS AND METHODS FOR DETECTING A POLYMORPHIC PROTEIN
    Publication number: 20110294145
    Abstract: The present invention provides antibodies that differentially react with allelic variants of a polymorphic protein, methods of identifying same, an antigen binding fragment comprised therein, proteins, cells, viral particles, compositions, and kits comprising same. The invention also provides methods for determining a haptoglobin type of a subject and methods for testing a subject for susceptibility to diabetic complications.
    Type: Application
    Filed: June 11, 2009
    Publication date: December 1, 2011
    Inventors: Jacob Victor, Noah Berkowitz, Andrew Levy
  • Glutathione peroxidase mimetics and uses thereof
    Patent number: 7923442
    Abstract: This invention relates to novel organoselenium and tellurium compounds, processes of producing the same and methods of use thereof. The compounds function as mimetics for the catalyst selenoenzyme glutathione peroxidase, which protects cells from oxidative stress.
    Type: Grant
    Filed: October 6, 2006
    Date of Patent: April 12, 2011
    Assignee: UTI Limited Partnership
    Inventors: Dusan Kuzma, Thomas G. Back, Noah Berkowitz
  • Use of haptoglobin genotyping in diagnosis and treatment of defective reverse cholesterol transport (RCT)
    Publication number: 20090074740
    Abstract: A method of determining a potential of a nondiabetic or diabetic patient to benefit from reverse cholesterol transport therapy for treatment of a vascular complication, followed by methods and compositions of treating the diagnosed vascular complications comprising determining a haptoglobin phenotype of the patient. Reverse cholesterol transport therapy includes inhibition of cholesteryl ester transport protein, such as by using the compound torcetrapib.
    Type: Application
    Filed: May 14, 2008
    Publication date: March 19, 2009
    Inventors: Noah Berkowitz, Andrew Levy
  • Use of haptoglobin genotyping in diagnosis and treatment of intraplaque hemorrhage resulting from plaque rupture
    Publication number: 20090054390
    Abstract: This invention relates to methods for providing prognosis of a subjects susceptibility to plaque rupture and compositions for treating plaque rupture and intraplaque hemorrhage. Specifically, the invention is directed to the use of haptoglobin genotyping in determining the susceptibility of a subject to develop intraplaque hemorrhage resulting from plaque rapture and treatment of the intraplaque hemorrhage using antioxidants.
    Type: Application
    Filed: June 5, 2008
    Publication date: February 26, 2009
    Inventors: Andrew Levy, Noah Berkowitz
  • Haptoglobin genotyping for prognosis and treatment of chronic vasospasm following subarachnoid hemorrhage (SAH)
    Publication number: 20090018110
    Abstract: This invention relates to methods and systems for providing a prognosis to a subject on developing vasospasm as a results of hemorrhagic event, and compounds and compositions for treatment thereof. Specifically, the invention relates to the use of haptoglobin genotyping in the prognosis of the development of vasospasm following SAH, and antioxidants such as glutathione peroxidase mimetics for treatment.
    Type: Application
    Filed: June 5, 2008
    Publication date: January 15, 2009
    Inventors: Andrew Levy, Noah Berkowitz
  • Glutathione peroxidase mimetics for treatment of neurodegenerative, pulmonary and inflammatory diseases
    Publication number: 20080234283
    Abstract: This invention relates to compositions and methods for the treatment of neurodegenerative, pulmonary and inflammatory diseases described herein with glutathione peroxidase and its mimetics.
    Type: Application
    Filed: February 19, 2008
    Publication date: September 25, 2008
    Inventor: Noah Berkowitz
  • Glutathione peroxidase mimetics for the treatment of dermatoses
    Publication number: 20080207679
    Abstract: This invention relates to compositions and methods for the treatment of dermatological conditions with a glutathione peroxidase mimetic.
    Type: Application
    Filed: February 19, 2008
    Publication date: August 28, 2008
    Inventor: Noah Berkowitz
  • Glutathione peroxidase mimetics and uses thereof
    Publication number: 20070123501
    Abstract: This invention relates to novel organoselenium and tellurium compounds, processes of producing the same and methods of use thereof. The compounds function as mimetics for the catalyst selenoenzyme glutathione peroxidase, which protects cells from oxidative stress.
    Type: Application
    Filed: October 6, 2006
    Publication date: May 31, 2007
    Inventors: Dusan Kuzma, Thomas Back, Noah Berkowitz
  • Reduction in myocardial infarction size
    Publication number: 20070014764
    Abstract: This invention provides methods and compositions used for reducing the Myocaidial Infarct (MI) size in diabetic subjects exhibiting the haptoglobin (Hp) 2 allele. Specifically, the invention relates to reduction of MI in diabetic subjects carrying the Hp-2 allele by reducing the oxidative sterss in these subjects following ischemia-reperfusion injury.
    Type: Application
    Filed: July 18, 2005
    Publication date: January 18, 2007
    Inventors: Andrew Levy, Noah Berkowitz