Patents by Inventor Noah Hoffman

Noah Hoffman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF DETERMINING TREATMENT OUTCOME
    Publication number: 20240076747
    Abstract: Provided herein are methods of determining treatment outcome in a subject having a disease, the method including evaluating RNA expression level of a B cell related gene to determine a B cell gene signature; evaluating RNA expression level of a CD8+ T cell related gene to determine a CD8+ T cell gene signature; analyzing the B cell gene signature and the CD8+ T cell gene signature (B8T gene signature); and determining treatment outcome in a subject based on the B8T gene signature.
    Type: Application
    Filed: March 10, 2022
    Publication date: March 7, 2024
    Inventors: Burles Johnson, Adam Aragaki, David McConkey, Noah Hahn, Jean Hoffman-Censits
  • Polypeptides having a functional domain of interest and methods of identifying and using same
    Publication number: 20090264303
    Abstract: Novel polypeptides having functional domains of interest are described, along with DNA sequences that encode the same. A method of identifying these polypeptides by means of a sequence-independent (that is, independent of the primary sequence of the polypeptide sought), recognition unit-based functional screen is also disclosed. Various applications of the method and of the polypeptides identified are described, including their use in assay kits for drug discovery, modification, and refinement.
    Type: Application
    Filed: May 21, 2007
    Publication date: October 22, 2009
    Inventors: Andrew B. Sparks, Noah Hoffman, Brian K. Kay, Dana M. Fowlkes, Stephen J. McConnell
  • Polypeptides having a functional domain of interest and methods of identifying and using same
    Patent number: 7223547
    Abstract: Novel polypeptides having functional domains of interest are described, along with DNA sequences that encode the same. A method of identifying these polypeptides by means of a sequence-independent (that is, independent of the primary sequence of the polypeptide sought), recognition unit-based functional screen is also disclosed. Various applications of the method and of the polypeptides identified are described, including their use in assay kits for drug discovery, modification, and refinement.
    Type: Grant
    Filed: March 23, 2004
    Date of Patent: May 29, 2007
    Assignees: Cytogen Corporation, University of North Carolina at Chapel Hill
    Inventors: Andrew B. Sparks, Noah Hoffman, Brian K. Kay, Dana M. Fowlkes, Stephen J. McConnell
  • Polypeptides having a functional domain of interest and methods of identifying and using same
    Publication number: 20040157216
    Abstract: Novel polypeptides having functional domains of interest are described, along with DNA sequences that encode the same. A method of identifying these polypeptides by means of a sequence-independent (that is, independent of the primary sequence of the polypeptide sought), recognition unit-based functional screen is also disclosed. Various applications of the method and of the polypeptides identified are described, including their use in assay kits for drug discovery, modification, and refinement.
    Type: Application
    Filed: March 23, 2004
    Publication date: August 12, 2004
    Inventors: Andrew B. Sparks, Noah Hoffman, Brian K. Kay, Dana M. Fowlkes, Stephen J. McConnell
  • Polypeptides having a functional domain of interest and methods of identifying and using same
    Patent number: 6709821
    Abstract: Novel polypeptides having functional domains of interest are described, along with DNA sequences that encode the same. A method of identifying these polypeptides by means of a sequence-independent (that is, independent of the primary sequence of the polypeptide sought), recognition unit-based functional screen is also disclosed. Various applications of the method and of the polypeptides identified are described, including their use in assay kits for drug discovery, modification, and refinement.
    Type: Grant
    Filed: June 13, 2001
    Date of Patent: March 23, 2004
    Assignees: University of North Carolina at Chapel Hill, Cytogen Corp.
    Inventors: Andrew B. Sparks, Noah Hoffman, Brian K. Kay, Dana M. Fowlkes, Stephen J. McConnell
  • Polypeptides having a functional domain of interest and methods of identifying and using same
    Publication number: 20020034755
    Abstract: Novel polypeptides having functional domains of interest are described, along with DNA sequences that encode the same. A method of identifying these polypeptides by means of a sequence-independent (that is, independent of the primary sequence of the polypeptide sought), recognition unit-based functional screen is also disclosed. Various applications of the method and of the polypeptides identified are described, including their use in assay kits for drug discovery, modification, and refinement.
    Type: Application
    Filed: June 13, 2001
    Publication date: March 21, 2002
    Inventors: Andrew B. Sparks, Noah Hoffman, Brian K. Kay, Dana M. Fowlkes, Stephen J. McConnell
  • Polypeptides having a functional domain of interest and methods of identifying and using same
    Patent number: 6309820
    Abstract: Novel polypeptides having functional domains of interest are described, along with DNA sequences that encode the same. A method of identifying these polypeptides by means of a sequence-independent (that is, independent of the primary sequence of the polypeptide sought), recognition unit-based functional screen is also disclosed. Various applications of the method and of the polypeptides identified are described, including their use in assay kits for drug discovery, modification, and refinement.
    Type: Grant
    Filed: April 3, 1996
    Date of Patent: October 30, 2001
    Assignees: University of North Carolina at Chapel Hill, Cytogen Corp.
    Inventors: Andrew B. Sparks, Noah Hoffman, Brian K. Kay, Dana M. Fowlkes, Stephen J. McConnell