Patents by Inventor Nobalanda Betty MOKOENA

Nobalanda Betty MOKOENA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PLANT-PRODUCED CHIMAERIC ORBIVIRUS VLPS
    Publication number: 20210388366
    Abstract: This invention relates to a second generation, plant-produced synthetic Orbivirus candidate vaccine. The vaccine comprises a plant produced chimaeric Orbivirus virus like particle (VLP) comprising at least one structural protein from one Orbivirus serotype and at least one structural protein selected from another serotype of the Orbivirus, wherein both structural capsid proteins are from the same Orbivirus species. In particular the invention relates to a vaccine against an Orbivirus, a method of producing chimaeric Orbivirus virus-like particles (VLPs) for use in a method of prevention and/or treatment of an Orbivirus infection, the use of the chimaeric Orbivirus VLPs in the manufacture of a vaccine for an Orbivirus, and a method of preventing and/or treating an Orbivirus infection.
    Type: Application
    Filed: June 1, 2021
    Publication date: December 16, 2021
    Applicants: CSIR, UNIVERSITY OF CAPE TOWN, ONDERSTEPOORT BIOLOGICAL PRODUCTS SOC LTD
    Inventors: Albertha René VAN ZYL, Ann Elizabeth MEYERS, Daria Anna RUTKOWSKA, Edward Peter RYBICKI, Hester Catharina STARK, Martha Magaretha O'KENNEDY, Nobalanda Betty MOKOENA
  • Plant-produced chimaeric Orbivirus VLPs
    Patent number: 11053509
    Abstract: This invention relates to a second generation, plant-produced synthetic Orbivirus candidate vaccine. The vaccine comprises a plant produced chimaeric Orbivirus virus like particle (VLP) comprising at least one structural protein from one Orbivirus serotype and at least one structural protein selected from another serotype of the Orbivirus, wherein both structural capsid proteins are from the same Orbivirus species. In particular the invention relates to a vaccine against an Orbivirus, a method of producing chimaeric Orbivirus virus-like particles (VLPs) for use in a method of prevention and/or treatment of an Orbivirus infection, the use of the chimaeric Orbivirus VLPs in the manufacture of a vaccine for an Orbivirus, and a method of preventing and/or treating an Orbivirus infection.
    Type: Grant
    Filed: April 19, 2017
    Date of Patent: July 6, 2021
    Assignees: CSIR, UNIVERSITY OF CAPE TOWN, ONDERSTEPOORT BIOLOGICAL PRODUCTS SOC LTD
    Inventors: Albertha René Van Zyl, Ann Elizabeth Meyers, Daria Anna Rutkowska, Edward Peter Rybicki, Hester Catharina Stark, Martha Magaretha O'Kennedy, Nobalanda Betty Mokoena
  • PLANT-PRODUCED CHIMAERIC ORBIVIRUS VLPS
    Publication number: 20190136246
    Abstract: This invention relates to a second generation, plant-produced synthetic Orbivirus candidate vaccine. The vaccine comprises a plant produced chimaeric Orbivirus virus like particle (VLP) comprising at least one structural protein from one Orbivirus serotype and at least one structural protein selected from another serotype of the Orbivirus, wherein both structural capsid proteins are from the same Orbivirus species. In particular the invention relates to a vaccine against an Orbivirus, a method of producing chimaeric Orbivirus virus-like particles (VLPs) for use in a method of prevention and/or treatment of an Orbivirus infection, the use of the chimaeric Orbivirus VLPs in the manufacture of a vaccine for an Orbivirus, and a method of preventing and/or treating an Orbivirus infection.
    Type: Application
    Filed: April 19, 2017
    Publication date: May 9, 2019
    Applicants: CSIR, UNIVERSITY OF CAPE TOWN, ONDERSTEPOORT BIOLOGICAL PRODUCTS SOC LTD
    Inventors: Albertha René VAN ZYL, Ann Elizabeth MEYERS, Daria Anna RUTKOWSKA, Edward Peter RYBICKI, Hester Catharina STARK, Martha Magaretha O'KENNEDY, Nobalanda Betty MOKOENA