Patents by Inventor Nobert Zander

Nobert Zander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation
    Publication number: 20120046235
    Abstract: Conjugates of an active substance and hydroxyalkyl starch (HAS) are provided herein. The active substance and the HAS are linked by a chemical moiety having a structure according to formula (I) wherein Y is O or S, and X is SH or (F). The conjugate has a structure according to formula (IV) wherein HAS? is a residue of HAS or a derivative thereof linked to the thioester group, and AS? is a residue of the active substance or derivative thereof linked to the alpha-X beta-amino group; or a structure according to formula (V) wherein HAS? is a residue of HAS or derivative thereof linked to the alpha-X beta-amino group, and AS? is a residue of the active substance or derivative thereof linked to the thioester group, and wherein the group —(C?Y) is derived from the thioester group —(C?Y)—S—R? and the group HN—CH—CH2—X is derived from the alpha-X beta amino group.
    Type: Application
    Filed: September 8, 2006
    Publication date: February 23, 2012
    Inventors: Nobert Zander, Ronald Frank
  • Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation
    Publication number: 20100311670
    Abstract: Conjugates of an active substance and hydroxyalkyl starch (HAS) are provided herein. The active substance and the HAS are linked by a chemical moiety having a structure according to formula (I) wherein Y is O or S, and X is SH or (F). The conjugate has a structure according to formula (IV) wherein HAS? is a residue of HAS or a derivative thereof linked to the thioester group, and AS? is a residue of the active substance or derivative thereof linked to the alpha-X beta-amino group; or a structure according to formula (V) wherein HAS? is a residue of HAS or derivative thereof linked to the alpha-X beta-amino group, and AS? is a residue of the active substance or derivative thereof linked to the thioester group, and wherein the group —(C?Y) is derived from the thioester group —(C?Y)—S—R? and the group HN—CH—CH2—X is derived from the alpha-X beta amino group.
    Type: Application
    Filed: September 8, 2006
    Publication date: December 9, 2010
    Inventors: Nobert Zander, Ronald Frank