Patents by Inventor Noboru Hoshi
Noboru Hoshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8552102Abstract: The present invention relates to a novel resin composition useful as a coating agent or a binder for medicines, drugs for animals, agricultural chemicals, fertilizers, foods or the like, which contains a polyvinyl alcohol copolymer as a main component. More particularly, the present invention relates to a resin composition, characterized in that the composition is obtained by copolymerizing a polyvinyl alcohol having an average polymerization degree of 1300 or less, and at least one polymerizable vinyl monomer in a weight ratio of 6:4 to 9:1.Type: GrantFiled: August 31, 2012Date of Patent: October 8, 2013Assignees: Shionogi & Co., Ltd., Nisshin Kasei Co., Ltd., Daido Chemical CorporationInventors: Makoto Noami, Toshiro Fujii, Yoshihiro Furuya, Noboru Hoshi, Toshio Shimamoto, Shunji Uramatsu
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Publication number: 20120329936Abstract: The present invention relates to a novel resin composition useful as a coating agent or a binder for medicines, drugs for animals, agricultural chemicals, fertilizers, foods or the like, which contains a polyvinyl alcohol copolymer as a main component. More particularly, the present invention relates to a resin composition, characterized in that the composition is obtained by copolymerizing a polyvinyl alcohol having an average polymerization degree of 1300 or less, and at least one polymerizable vinyl monomer in a weight ratio of 6:4 to 9:1.Type: ApplicationFiled: August 31, 2012Publication date: December 27, 2012Inventors: Makoto Noami, Toshiro Fujii, Yoshihiro Furuya, Noboru Hoshi, Toshio Shimamoto, Shunji Uramatsu
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Patent number: 8277844Abstract: The present invention relates to a novel resin composition useful as a coating agent or a binder for medicines, drugs for animals, agricultural chemicals, fertilizers, foods or the like, which contains a polyvinyl alcohol copolymer as a main component. More particularly, the present invention relates to a resin composition, characterized in that the composition is obtained by copolymerizing a polyvinyl alcohol having an average polymerization degree of 1300 or less, and at least one polymerizable vinyl monomer in a weight ratio of 6:4 to 9:1.Type: GrantFiled: August 5, 2004Date of Patent: October 2, 2012Assignees: Shionogi & Co., Ltd., Nisshin Kasei Co., Ltd., Daido Chemical CorporationInventors: Makoto Noami, Toshiro Fujii, Yoshihiro Furuya, Noboru Hoshi, Toshio Shimamoto, Shunji Uramatsu
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Publication number: 20060229383Abstract: The present invention relates to a novel resin composition useful as a coating agent or a binder for medicines, drugs for animals, agricultural chemicals, fertilizers, foods or the like, which contains a polyvinyl alcohol copolymer as a main component. More particularly, the present invention relates to a resin composition, characterized in that the composition is obtained by copolymerizing a polyvinyl alcohol having an average polymerization degree of 1300 or less, and at least one polymerizable vinyl monomer in a weight ratio of 6:4 to 9:1.Type: ApplicationFiled: August 5, 2004Publication date: October 12, 2006Inventors: Makoto Noami, Toshiro Fujii, Yoshihiro Furuya, Noboru Hoshi, Toshio Shimamoto, Shunji Uramatsu
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Patent number: 6977721Abstract: A foreign substance inspection apparatus 1 which obtains images of a powder material with a two-dimensional camera 17 and subjects the image data outputted from the camera 17 to image processing, whereby foreign substances mixed into the powder material are detected. The foreign substance inspection apparatus 1 comprises a rotatably supported container 5 with an opening surface in a substantially horizontal state; a liftably supported lift member 7 inside the container; a drive control device for controlling rotation of the container 5 and rise and fall of the lift member 7; and a scraping plate 25 disposed on the opening surface 3 of the container 5. The two-dimensional camera 17 is located so as to obtain images of the surface of the powder material that is exposed on the opening surface 3.Type: GrantFiled: July 21, 2003Date of Patent: December 20, 2005Assignees: Mingtai Chemical Co., Ltd., Nisshin Kasei Co., Ltd.Inventors: Hsin Tan Chou, Cheng Yu Chen, Taizo Yamamoto, Noboru Hoshi, Kohachi Kawamura
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Patent number: 6967026Abstract: A hard capsule which is made mainly of a polymer or copolymer obtained by polymerizing or copolymerizing at least one polymerizable vinyl monomer in the presence of polyvinyl alcohol and/or a derivative thereof. Unlike conventional hard capsules, this hard capsule can be filled with a solvent (e.g., polyethylene glycol) for a sparingly soluble drug ingredient.Type: GrantFiled: August 24, 2001Date of Patent: November 22, 2005Assignees: Nisshin Kasel Co., Ltd., Daido Chemical CorporationInventors: Noboru Hoshi, Toshio Shimamoto, Shigeru Sugiyama
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Publication number: 20050186268Abstract: A method of manufacturing a hard capsule made mainly of a polymer or copolymer obtained includes polymerizing or copolymerizing at least one polymerizable vinyl monomer in the presence of polyvinyl alcohol and/or a derivative thereof. Unlike conventional hard capsules, this hard capsule can be filled with a solvent (e.g., polyethylene glycol) for a sparingly soluble drug ingredient.Type: ApplicationFiled: April 20, 2005Publication date: August 25, 2005Inventors: Noboru Hoshi, Toshio Shimamoto, Shigeru Sugiyama
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Publication number: 20040085531Abstract: The present invention provides a foreign substance inspection apparatus 1 which obtains images of a powder material with a two-dimensional camera 17 and subjects the image data outputted from the camera 17 to image processing, whereby foreign substances mixed into the powder material are detected. The foreign substance inspection apparatus 1 comprises a rotatably supported container 5 with an opening surface in a substantially horizontal state; a liftably supported lift member 7 inside the container; a drive control device for controlling rotation of the container 5 and rise and fall of the lift member 7; a scraping plate 25 disposed on the opening surface 3 of the container 5; wherein the powder material contained in the container 5 is pushed upward with the rise of the lift member so as to be scraped with the scraping plate 25, and the two-dimensional camera 17 is located so as to obtain images of the surface of the powder material that is exposed on the opening surface 3.Type: ApplicationFiled: July 21, 2003Publication date: May 6, 2004Inventors: Hsin Tan Chou, Cheng Yu Chen, Taizo Yamamoto, Noboru Hoshi, Kohachi Kawamura
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Publication number: 20030166763Abstract: A hard capsule which is made mainly of a polymer or copolymer obtained by polymerizing or copolymerizing at least one polymerizable vinyl monomer in the presence of polyvinyl alcohol and/or a derivative thereof. Unlike conventional hard capsules, this hard capsule can be filled with a solvent (e.g., polyethylene glycol) for a sparingly soluble drug ingredient.Type: ApplicationFiled: February 19, 2003Publication date: September 4, 2003Inventors: Noboru Hoshi, Toshio Shimamoto, Shigeru Sugiyama
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Patent number: 4917885Abstract: In place of gelatin conventionally used as a material for shaping hard medicinal capsules, the invention proposes a hard capsule for medicinal use shaped of a polymer blend of a water-soluble cellulose ether, e.g., alkyl cellulose, hydroxyalkyl cellulose and alkyl hydroxyalkyl cellulose, and a polyvinyl alcohol in a weight ratio of 70:30 to 98:2. The inventive hard medicinal capsules have remarkably low permeability to oxygen and moisture with little influences on the medicament contained therein along with sufficiently high mechanical strengths and are much more stable than conventional gelatin-made capsules against the influences of the ambient conditions, such as, the crack formation unavoidable in a gelatin-made hard capsule when it is kept under an extremely low humidity.Type: GrantFiled: December 23, 1986Date of Patent: April 17, 1990Assignee: Shin-Etsu Chemical Co., Ltd.Inventors: Tohru Chiba, Hiroaki Muto, Soji Tanioka, Yuichi Nishiyama, Noboru Hoshi, Yoshiro Onda
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Patent number: 4405597Abstract: The invention provides a novel means for the administration of a therapeutically effective ingredient in the form of a rectally applicable medicament capsule, in which the otherwise unavoidable extreme variation in the absorbability of the effective ingredient among the individuals rectally treated with the capsules is minimized. It has been unexpectedly found that, when the effective ingredient is contained in the capsule in the form of a liquid medicine, the osmotic pressure of the liquid content plays a very essential role in the absorption of the effective ingredient through the rectum and the variation in the absorbability of the effective ingredient among the individuals can be minimized when the osmotic pressure of the liquid content is substantially higher than the osmotic pressure of the rectal fluid with which the capsules are contacted.Type: GrantFiled: August 11, 1981Date of Patent: September 20, 1983Assignee: Shin-Etsu Chemical Co., Ltd.Inventors: Yasushi Takagishi, Yoshio Doi, Kiichiro Ohsuga, Noboru Hoshi, Shionogi & Co., Ltd.
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Patent number: 4402692Abstract: The invention provides a novel and efficient means for the administration of a therapeutically effective ingredient by rectal application in the form of a medicament capsule encapsulating the effective ingredient. The medicament capsule according to the invention is formed of a hard capsule shell made of a mixed ester of a cellulose ether, e.g. alkyl-, hydroxyalkyl- and hydroxyalkyl alkylcelluloses, esterified with aliphatic monacyl groups and acidic succinyl groups. When the capsule is inserted into the rectum, the capsule shell is disintegrated and the rectally absorbable effective ingredient is readily and smoothly released into the rectum and absorbed to exhibit therapeutical effects as efficiently as with conventional suppositories.Type: GrantFiled: June 2, 1981Date of Patent: September 6, 1983Assignees: Shionogi & Co., Ltd., Shin-Etsu Chemical Co., Ltd.Inventors: Yasushi Takagishi, Yoshio Doi, Kanji Aita, Noboru Hoshi
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Patent number: 4397835Abstract: The invention provides a novel means for overcoming the problem of undue and irregular delay in the exhibition of the effect of medicine when a patient is administrated with an enterosoluble hard-capsulated medicament. The unexpected discovery that the key parameter ruling the smooth transfer of an enterosoluble capsule from the stomach to the intestinal canals is the overall specific gravity of the capsule has led to the establishment of the invention which proposes an enterosoluble hard-capsulated medicament having an overall specific gravity of at least 1.05 or, preferably, at least 1.10.Type: GrantFiled: April 28, 1982Date of Patent: August 9, 1983Assignees: Shionogi & Co., Ltd., Shin-Etsu Chemical Co., Ltd.Inventors: Yasushi Takagishi, Yoshio Doi, Noboru Hoshi
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Patent number: 4339463Abstract: The invention provides a novel means for overcoming the problem of undue and irregular delay in the exhibition of the effect of medicine when a patient is administrated with an enterosoluble hard-capsulated medicament. The unexpected discovery that the key parameter ruling the smooth transfer of an enterosoluble capsule from the stomach to the intestinal canals is the overall specific gravity of the capsule has led to the establishment of the invention which proposes an enterosoluble hard-capsulated medicament having an overall specific gravity of at least 1.05 or, preferably, at least 1.10.Type: GrantFiled: July 16, 1980Date of Patent: July 13, 1982Assignees: Shionogi & Co., Ltd., Shin-Etsu Chemical Co., Ltd.Inventors: Yasushi Takagishi, Yoshio Doi, Noboru Hoshi
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Patent number: 4176175Abstract: The sugar-coated solid dosage forms have improved disintegrability even in a neutral medium after prolonged storage, with sugar-coating layers having excellent mechanical strengths. The coating layer that is in direct contact with the surface of the solid dosage form contains a water-insoluble hydroxypropyl cellulose with a relatively low content of hydroxypropoxy groups, say, from 4 to 16% by weight. The hydroxypropyl cellulose is used by being suspended in the coating syrup or mixed in the dusting powder for purposes of subcoating. It is also possible to use the hydroxypropyl cellulose in the form of suspension to form a smoothing coat.Type: GrantFiled: June 6, 1977Date of Patent: November 27, 1979Assignees: Shionogi & Co., Ltd., Shin-Etsu Chemical Co., Ltd.Inventors: Hideyuki Maekawa, Kinzaburo Noda, Noboru Hoshi
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Patent number: 4017598Abstract: Methylcellulose with or without the addition of medically active ingredients and other additives is first granulated by a known method into granules of appropriate size and then the granules are blended with a disintegrator and compressed into tablets. The tablets obtained by the method have sufficient hardness and very short disintegration time when taken into the human body in comparison with the poor disintegrability of tablets directly shaped from powdery methylcellulose or a methylcellulose-based mixture of active ingredients. The method is useful for tableting some medicinals of poor tabletability, such as, pancreatin which require large amounts of a binder to be successfully shaped into tablets. Tablets of methylcellulose prepared in accordance with the method can find use as a non-caloried food.Type: GrantFiled: April 22, 1975Date of Patent: April 12, 1977Assignee: Shin-Etsu Chemical Company LimitedInventors: Shigeru Ohno, Noboru Hoshi, Fujio Sekigawa
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Patent number: 4017647Abstract: Enteric coatings are provided on solid pharmaceutical dosage forms by a method comprising covering the dosage froms with an aqueous solution of a polymeric substance having carboxyl groups in the watersoluble salt form and contacting the thus coated dosage forms with an inorganic acid to convert the polymeric substance into the water-insoluble acid form. The coating solution includes no organic solvent, and this method is safe from dangers of fires or explosions and air pollution.Type: GrantFiled: June 9, 1975Date of Patent: April 12, 1977Assignee: Shin-Etsu Chemical Company LimitedInventors: Shigeru Ohno, Noboru Hoshi, Fujio Sekigawa
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Patent number: 3957523Abstract: When a mixture comprising 30 to 70% by weight of an enterosoluble cellulose derivative containing a monoester linkage with a polybasic acid, such as, hydroxypropyl methylcellulose phthalate, and 70 to 30% by weight of a digestive fluid-insoluble cellulose derivative, such as, ethylcellulose is used as a coating material for solid medicines, the rate of gradual release of active ingredients of the medicine in the intestinal tracts can be appropriately controlled.Type: GrantFiled: March 28, 1974Date of Patent: May 18, 1976Assignee: Shinetsu Chemical CompanyInventors: Shigeru Ohno, Noboru Hoshi, Fujio Sekigawa