Patents by Inventor Noboru Nakaigawa

Noboru Nakaigawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Blood biomarker for use in evaluation of effect of drug therapy on kidney cancer
    Patent number: 11061034
    Abstract: Disclosed are methods for determining the efficacy of a pharmacotherapy drug for kidney cancer using a blood test. The methods include the evaluation of the effect of a drug therapy for the treatment of kidney cancer by measuring the PARK7 level in a blood sample taken from a patient with kidney cancer who receives the drug therapy for the treatment of kidney cancer. An increased PARK7 level indicates that the drug therapy is not effective. Moreover, by using the blood PARK7 level as an indicator, the efficacy of a candidate substance for a therapeutic agent for kidney cancer can also be determined.
    Type: Grant
    Filed: October 11, 2016
    Date of Patent: July 13, 2021
    Assignee: PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY
    Inventors: Noboru Nakaigawa, Daiki Ueno, Masahiro Yao
  • RENAL CANCER DETECTION METHOD AND TEST DRUG
    Publication number: 20210063400
    Abstract: An object of the present invention is to provide a method for detecting renal cancer, and a reagent that can be used for the method. Provided is a method for detecting renal cancer, which includes measuring the amount of TFPI2 in a sample derived from a patient. An antibody that specifically recognizes NT-TFPI2 and intact TFPI2 is included in a detection reagent for renal cancer.
    Type: Application
    Filed: December 26, 2018
    Publication date: March 4, 2021
    Applicants: PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY, TOSOH CORPORATIO
    Inventors: Noriaki ARAKAWA, Hisashi HIRANO, Noboru NAKAIGAWA, Masahiro YAO, Norihisa OHTAKE
  • BLOOD BIOMARKER FOR USE IN EVALUATION OF EFFECT OF DRUG THERAPY ON KIDNEY CANCER
    Publication number: 20180321246
    Abstract: Disclosed is a means whereby the efficacy of a pharmacotherapy drug for kidney cancer can be easily determined by a blood test. A method of assisting the evaluation of the effect of a drug therapy for the treatment of kidney cancer according to the present invention comprises measuring the PARK7 level in a blood sample taken from a patient with kidney cancer who receives the drug therapy for the treatment of kidney cancer. An increased PARK7 level indicates that the drug therapy is not effective. Moreover, by using the blood PARK7 level as an indicator, the efficacy of a candidate substance for a therapeutic agent for kidney cancer can also be determined.
    Type: Application
    Filed: October 11, 2016
    Publication date: November 8, 2018
    Applicant: PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY
    Inventors: Noboru NAKAIGAWA, Daiki UENO, Masahiro YAO
  • Anticancer agents
    Patent number: 7812044
    Abstract: Remedies/preventives for hormone-independent cancer, hormone-independent cancer cell proliferation inhibitors, apoptosis inducers for cancer cells, etc. each containing a compound having an angiotensin II antagonism, its prodrug or a salt thereof. Thus, excellent anticancer agents are provided.
    Type: Grant
    Filed: November 12, 2002
    Date of Patent: October 12, 2010
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Yoshinobu Kubota, Hiroji Uemura, Noboru Nakaigawa, Kenichiro Naito
  • Anticancer agents
    Publication number: 20050119323
    Abstract: Remedies/preventives for hormone-independent cancer, hormone-independent cancer cell proliferation inhibitors, apoptosis inducers for cancer cells, etc. each containing a compound having an angiotensin II antagonism, its prodrug or a salt thereof. Thus, excellent anticancer agents are provided.
    Type: Application
    Filed: November 12, 2002
    Publication date: June 2, 2005
    Inventors: Yoshinobu Kubota, Hiroji Uemura, Noboru Nakaigawa, Kenichiro Naito