Patents by Inventor Noboru Otake

Noboru Otake has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4366311
    Abstract: A novel compound of the formula ##STR1## and the salts thereof, derived from dianemycin, are useful as antiprotozoal and antibacterial agents.
    Type: Grant
    Filed: September 18, 1981
    Date of Patent: December 28, 1982
    Assignee: Taisho Pharmaceutical Co., Ltd.
    Inventors: Taku Mizutani, Michio Yamagishi, Kazutoshi Mizoue, Akira Kawashima, Sadafumi Omura, Noboru Otake, Haruo Seto
  • Patent number: 4359583
    Abstract: The novel antibiotics represented by the formula ##STR1## wherein either (a) R.sup.1 is hydroxy and R.sup.2 is hydrogen, or (b) R.sup.1 is methoxy and R.sup.2 is hydroxy, and the salt thereof, are produced by the cultivation of the organism Streptomyces hygroscopicus TM-531 under aerobic conditions. They are separated from coproduced Antibiotic TM-531 as disclosed in U.S. Pat. No. 4,269,971 and from each other by chromatography on silica gel.
    Type: Grant
    Filed: September 15, 1981
    Date of Patent: November 16, 1982
    Assignee: Taisho Pharmaceutical Co., Ltd.
    Inventors: Taku Mizutani, Michio Yamagishi, Kazutoshi Mizoue, Akira Kawashima, Sadafumi Omura, Noboru Otake, Haruo Seto
  • Patent number: 4269971
    Abstract: Antibiotic TM-531 having the formula: ##STR1## TM-531 is effective against gram-positive bacteria, plant pathogenic microorganisms and protozoa.
    Type: Grant
    Filed: December 31, 1979
    Date of Patent: May 26, 1981
    Assignee: Taisho Pharmaceutical Co., Ltd.
    Inventors: Michio Yamagishi, Akira Kawashima, Taku Mizutani, Hiroshi Hara, Kazutoshi Mizoue, Sadafumi Omura, Haruo Seto, Noboru Otake
  • Patent number: 4199515
    Abstract: Novel lonomycin derivatives, prepared by reacting lonomycin or its salt with an alkali or an alkali metal borohydride, show antibacterial, antiviral and antiprotozoal activity, and have decreased toxicity as compared with lonomycin.
    Type: Grant
    Filed: March 9, 1979
    Date of Patent: April 22, 1980
    Assignee: Taisho Pharmaceutical Co., Ltd.
    Inventors: Michio Yamagishi, Kazutoshi Mizoue, Taku Mizutani, Hiroshi Hara, Sadafumi Omura, Haruo Seto, Noboru Otake
  • Patent number: 4138496
    Abstract: SY-1 substance has the following formula: ##STR1## The SY-1 substance and esters and salts thereof are antibiotics which have antibacterial, antifungal, antiviral and anticoccidial activity and also increase feed-utilization efficiency in ruminants.
    Type: Grant
    Filed: June 21, 1977
    Date of Patent: February 6, 1979
    Assignee: Kaken Chemical Co., Ltd.
    Inventors: Akira Shibata, Yukio Miyazaki, Kiyoshi Tsuda, Noboru Otake, Haruyasu Kinashi