Patents by Inventor Noboru Uchiyama
Noboru Uchiyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220219914Abstract: A parts supply apparatus includes multiple parts containers configured to accommodate multiple parts, and a stage. The multiple parts containers are attached to the stage, and the multiple parts are scattered on the stage from the multiple parts containers.Type: ApplicationFiled: June 5, 2019Publication date: July 14, 2022Applicant: FUJI CORPORATIONInventor: Noboru UCHIYAMA
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Patent number: 8597576Abstract: An analyzer of the present invention for analyzing a glycan or a complex glycan includes a substrate, a fluorescent labeling excitation means and a fluorescent intensity measurement means. The substrate comprises a rectangle photoconductive base plate coated by a compound containing an active group to fix protein by an amino group thereof, one and more open-topped reaction vessel formed on a surface of the base plate, and plural spots of glycan binding proteins arranged in a matrix and immobilized on the surface of the base plate in the reaction vessel. The fluorescent labeling excitation means which excites fluorescent label by generating evanescent-waves on the surface of the substrate comprises a pair of optical fibers arranged toward the both side end faces of the right and left of the substrate to introduce a light thereinto.Type: GrantFiled: August 19, 2011Date of Patent: December 3, 2013Assignee: National Institute of Advanced Industrial Science and TechnologyInventors: Jun Hirabayashi, Atsushi Kuno, Noboru Uchiyama
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Publication number: 20120053089Abstract: An analyzer of the present invention for analyzing a glycan or a complex glycan includes a substrate, a fluorescent labeling excitation means and a fluorescent intensity measurement means. The substrate comprises a rectangle photoconductive base plate coated by a compound containing an active group to fix protein by an amino group thereof, one and more open-topped reaction vessel formed on a surface of the base plate, and plural spots of glycan binding proteins arranged in a matrix and immobilized on the surface of the base plate in the reaction vessel. The fluorescent labeling excitation means which excites fluorescent label by generating evanescent-waves on the surface of the substrate comprises a pair of optical fibers arranged toward the both side end faces of the right and left of the substrate to introduce a light thereinto.Type: ApplicationFiled: August 19, 2011Publication date: March 1, 2012Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Jun Hirabayashi, Atsushi Kuno, Noboru Uchiyama
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Patent number: 8008094Abstract: As a result of investigating the optimum conditions of methods for immobilizing proteins that interact with sugar chains onto a substrate, it was revealed that coating the surface of a slide glass with GTMS enables immobilization at a higher S/N ratio than conventionally possible. Moreover, by using a substrate to which a rubber with a number of holes was affixed to form a number of reaction vessels, and further by spotting lectins onto the substrate and washing with PBST, the weak interactions between sugar chains and lectins were successfully detected with improved sensitivity. In addition, by introducing an evanescent excitation-type scanner, it became possible to detect the interactions between lectins and sugar chains without washing away the probe solution.Type: GrantFiled: December 24, 2004Date of Patent: August 30, 2011Assignee: National Institute of Advanced Industrial Science and TechnologyInventors: Jun Hirabayashi, Atsushi Kuno, Sachiko Nakamura, Noboru Uchiyama
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Publication number: 20090041630Abstract: An analyzer for a glycan or a complex carbohydrate which comprises a substrate made of a photoconductive material having multiple types of glycan binding proteins provided and immobilized thereon a means of conducting light into the side edge face of the substrate and generating an evanescent wave on the substrate surface to thereby excite fluorescent labels, and a fluorescent intensity-measuring means of measuring the intensity of the fluorescence induced by the above means for each of the positions of the glycan binding proteins provided as described above. By using this analyzer, a glycan or a complex carbohydrate can be conveniently, quickly, highly sensitively and highly accurately analyzed.Type: ApplicationFiled: June 14, 2006Publication date: February 12, 2009Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Jun Hirabayashi, Atsushi Kuno, Noboru Uchiyama
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Publication number: 20070202535Abstract: As a result of investigating the optimum conditions of methods for immobilizing proteins that interact with sugar chains onto a substrate, it was revealed that coating the surface of a slide glass with GTMS enables immobilization at a higher S/N ratio than conventionally possible. Moreover, by using a substrate to which a rubber with a number of holes was affixed to form a number of reaction vessels, and further by spotting lectins onto the substrate and washing with PBST, the weak interactions between sugar chains and lectins were successfully detected with improved sensitivity. In addition, by introducing an evanescent excitation-type scanner, it became possible to detect the interactions between lectins and sugar chains without washing away the probe solution.Type: ApplicationFiled: December 24, 2004Publication date: August 30, 2007Applicant: National Institute of Advanced Industrial Science and TechnologyInventors: Jun Hirabayashi, Atsushi Kuno, Sachiko Nakamura, Noboru Uchiyama
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Publication number: 20070167608Abstract: The present inventors discovered that lectins recognize extremely small differences in sugar chain structures, and that by using this ability to recognize sugar chain structures, numerous sugar chain structures can be distinguished using the strong or weak interaction patterns of about ten types of lectins. Therefore, by reference to and use of control interaction data, in which large amounts of data on the interactions between sugar chains and lectins have been collected, the structures of subject sugar chains can be identified, estimated, and such with high accuracy.Type: ApplicationFiled: June 30, 2004Publication date: July 19, 2007Inventors: Jun Hirabayashi, Atsushi Kuno, Sachiko Nakamura, Noboru Uchiyama, Ken-ichi Kasai, Yoichiro Arata, Yoriko Takahashi
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Patent number: 4010971Abstract: The invention discloses a lifting device suspended from a crane and comprised of a lifting beam, the shackle suspending devices mounted upon the lifting beam and movable therealong toward or away from each other depending upon the distance of attaching holes of the like of a load to be lifted, shackle devices each rotatably attached to the lower end of each suspending device and including means for adjusting the angular position of the shackle device and means for advancing a shackle pin into the attaching hole or retracting it therefrom.Type: GrantFiled: May 20, 1975Date of Patent: March 8, 1977Assignee: Ishikawajima-Harima Jukogyo Kabushiki KaishaInventors: Yuzuru Kuwamoto, Noboru Uchiyama
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Patent number: 3962207Abstract: When hydrogen halide salts of L-aspartic anhydride are reacted with lower alkyl esters of L-phenylalanine to produce the corresponding L-aspartyl-L-phenylalanine esters, a significant increase in yield and in the proportion of the .alpha.-isomer to the .beta.-isomer is achieved when the reaction is carried out in the presence of a lower alkanol and of a strong acid, such as sulfuric acid, hydrogen chloride, or mono-esters of sulfuric acid with a lower alkanol.Type: GrantFiled: December 20, 1974Date of Patent: June 8, 1976Assignee: Ajinomoto Co., Inc.Inventors: Noboru Uchiyama, Masanori Nagao, Naomasa Mizoguchi