Abstract: In automatically filling and sealing pouches at high speed a pouch supporting base continuously and non-stoppably travels on a conveying path passing a pouch dropping operation station, a filling up operation station, a sealing operation station and a supporting base collecting station in turn. In the pouch dropping operation station, pouches are dropped into the pouch supporting base after being opened one by one. In the filling up operation station, a fixed amount of substances fills the pouches through the rotary filling up apparatus from the opened filling up mouth of the pouches held by the pouch supporting base. In the sealing operation station the filling up mouth of the pouches is hermetically sealed by the sealing operation system apparatus. In the pouch supporting base collecting station, filled up pouches held by the pouch supporting base are suspended and conveyed, and the empty pouch supporting bases are collected and returned to the pouch dropping operation station.