Abstract: A composition comprising Denhichi, Tochu and Osei, wherein the Denhichi is Panax pseudo-ginseng, the Tochu is Eucommiae ulmoides and the Osei is selected from the group consisting of Polygonati Rhizoma, Polygonatum falcatum, other plants belonging to the genus Polygonatum, and Siberian Solomonseal Rhizome.

Abstract: The invention provides a highly sensitive measurement and detection technique for dioxins, which has advantages inherent to immunoassay; and markers to be used in the technique.

Abstract: The present invention provides a highly sensitive immunoassay system for estrogens, which utilizes as a labeled compound a biotinylated estradiol derivative of the formula (1) wherein one of R1 and R2 is hydrogen and the other is a group represented by wherein R3s are the same or different and represent an arginine residue or a lysine residue, x is 0 or 1, y is an integer from 1 to 5, and z is an integer from 1 to 3.

Abstract: The present invention provides an immunoassay for phthalic acid esters, which comprises measuring the phthalic acid esters contained in a sample using an antibody produced with a conjugate of a carrier protein and a phthalic acid ester derivative represented by the formula wherein R1 and R2 may be the same or different and are hydrogen, alkyl, cycloalkyl or phenylalkyl, with the proviso that both of R1 and R2 are not hydrogen; m is an integer from 1 to 5; and Y is amino or carboxyl.

Abstract: The present invention provides a highly sensitive immunoassay system for estrogens, which utilizes as a labeled compound a biotinylated estradiol derivative of the formula (1) 1

Abstract: A composition comprising Denhichi, Tochu and Osei, wherein the Denhichi is Panax pseudo-ginseng, the Tochu is Eucommiae ulmoides and the Osei is selected from the group consisting of Polygonati Rhizoma, Polygonatum falcatum, other plants belonging to the genus Polygonatum, and Siberian Solomonseal Rhizome.

Abstract: A composition comprising “Panax Pseudo Ginseng” and “Eucommia Bark”, a composition comprising gallic acid-containing herbal extracts and “Licorice Root”, together with “Panax Pseudo Ginseng” and “Eucommia Bark”, a drink or food comprising the above composition, and medicines, food supplements, healthcare foods, mixing feed and feed for improvement of nutritional state, hypertension, high blood sugar, immune system and liver disorders.

Abstract: The present invention describes a monoclonal antibody which recognizes the C-terminal region of human glicentin. The antibody is useful for assaying for the presence of glicentin in a sample.

Abstract: Disclosed are an oncogene-related peptide characterized in that the peptide comprises a portion of the amino acid sequence of a gene product coded for by an oncogene, an antigen or immunogen formed from the oncogene-related peptide and a carrier, an antibody against such antigen or immunogen, and a method of determining a gene product coded for by an oncogene by an immunoreaction with use of such antibody.

Abstract: Novel peptides represented by the following formulaR.sub.1 --A--B--C--D--Trp--Met--Y (1)wherein; R.sub.1 denotes pGlu, X--R.sub.2 --CO--, X being carboxyl or amino and R.sub.2 being lower alkylene of 1-6 carbon atoms, or ##STR1## A denotes Asp, Ala, or merely a chemical bond; B denotes Tyr(SO.sub.3 H) or Phe(NHSO.sub.3 H); C denotes Met or merely a chemical bond; D denotes Gly, D--Ala, or D--Trp; and Y denotes NH.sub.2, Asp--NH.sub.2, or Asp--Phe--NH.sub.2 ; with the proviso that Y is NH.sub.2 or Asp--NH.sub.2 when R.sub.1 is pGlu, HOOC--R.sub.2 --CO--, or ##STR2## B is Tyr(SO.sub.3 H), C is Met, and D is Gly, and pharmacologically acceptable salts thereof.

Abstract: Polypeptides having partial or complete amino acid sequences related to the pre-acetylcholine receptor-.alpha. of the electric organ Torpedo californica are disclosed. These polypeptides having AChR antigenic properties are useful for the production and purification of antibodies to the acetylcholine receptor (AChR) as well as for the diagnosis of myastenia gravis (MG).

Abstract: This invention provides a peptide represented by the formulaR--Tyr(SO.sub.3 H)--Met--Gly--Trp--Met--Asp--W--NH.sub.2wherein R is HOOC--A--CO--Asp-- (wherein A is lower alkylene), pGlu--Asp--, HOOC--A--CO-- (wherein A is lower alkylene) or ##STR1## and W is Phe or N.sup..alpha. -lower alkyl-Phe, or a salt thereof, process for preparing the peptide and psychodepressant composition containing the peptide.The peptides of the invention are useful as psychodepressant drug, and especially effective for curing schizophrenia.

Abstract: A process for preparing a gut glucagon antigen composed of a peptide-carrier complex is disclosed, which comprises using as hapten a peptide represented by the following general formula;R-Lys-Arg-Asn-Lys-Asn-Asn-Ile-Ala-OHwherein R represents a hydrogen atom, an amino acid group or a peptide group containing 2 to 20 amino acid groups, and reacting it with a carrier in the presence of a binding agent for binding the hapten and the carrier to each other. Also, a process for preparing a gut glucagon antibody, which comprises administering the antigen described to mammals, and collecting the thus-produced antibody, is disclosed.

Abstract: Disclosed herein are the peptides possibly radio-labelled and having primary structures represented by the general formula (I):X-Ser-Gln-Gly-Gly-Ser-Asn-Y (I)wherein(1) X is H-Tyr-Gln-Ala-Lys and Y is a hydroxyl group,(2) X is pGlu-Ala-Lys(N.sup..epsilon. -Tyr-H) and Y is a hydroxyl group, or(3) X is pGlu-Ala-Lys and Y is Tyr-OH.These peptides can be synthesized by bonding a pre-determined amino acid or a peptide to the nitrogen at one of the two ends of the starting material, H-Asn-OH or H-Asn-Tyr-OH, while leaving the carboxyl group at the other end thereof in a free state, and by successively repeating the same procedure on the thus prepared peptides.The symbols, Ser, Gln, Gly, Asn, Tyr, Ala and Lys used herein represent respectively a divalent residue formed by removing one hydrogen atom from the amino group of and further removing one hydroxyl group from the carboxyl group of the respective alpha- amino acids, serine, glutamine, glycine, asparagine, tyrosine, alanine and lysine.

Abstract: A novel process for the production of cholecystokininpancreozymin C-terminal peptide amide sulfate esters in a high yield and through a simple operation is described. A protected peptide amide is reacted with sulfur trioxide-pyridine complex and resulting protected piptide amide sulfate ester is then isolated in the form of its calcium salt. Thereafter, the protecting groups and calcium are removed. Sulfuric acid resulting from unreacted sulfur trioxide-pyridine complex may be precipitated and easily removed in the form of calcium sulfate.

Abstract: A novel dopamine derivative compound having the following general formula and pharmacologically acceptable acid addition salt thereof: ##STR1## wherein X stands for a di- or tri-peptide residue derived from alanine, glycine, glutamine, isoleucine, lysine, leucine, tyrosine proline or valine, having an excellent activity of increasing the renal blood flow are provided.

Abstract: A peptide having an amino acid sequence of Arg-Arg-Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gl y-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-Lys-Arg; Tyr-Arg-Arg-Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pr o-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-Lys-Arg; or Tyr-Arg-Arg-Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gl y-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-Lys-Arg; and the N.sup..epsilon. formyl-Lys derivative thereof.

Abstract: This invention provides a peptide represented by the formulaR--Tyr(SO.sub.3 H)--Met--Gly--Trp--Met--Asp--W--NH.sub.2wherein R is HOOC--A--CO--Asp-- (wherein A is lower alkylene), pGlu--Asp--, HOOC--A--CO-- (wherein A is lower alkylene) or ##STR1## and W is Phe or N.sup..alpha. -lower alkyl-Phe, or a salt thereof, process for preparing the peptide and psychodepressant composition containing the peptide.The peptides of the invention are useful as psychodepressant drug, and especially effective for curing schizophrenia.