Abstract: A solid type nano-pore sequencer is arrayed easily. In a liquid column separation device including first and second base materials, a liquid feeding unit supplies fluids to a gap between the two base materials. Hydrophilic and hydrophobic regions are disposed on a surface of the second base material, and the hydrophilic region is disposed to oppose a predetermined position of the first base material where a substance to be measured is made to pass through. Also, a flow passage space includes at least one inlet and outlet through which fluids can flow in and out. A representative length of the hydrophilic region is made larger than a distance between the first and second base materials, and thereby a liquid column capable of connecting the first base material and the second base material is formed by making two or more immiscible fluids to flow by the liquid feed unit.

Abstract: A stirring and mixing device 110 comprises an introduction pipe 55 which is provided with a powder introduction port 24 and a liquid introduction port 22, an extrusion pipe 60 which is connected to the introduction pipe 55 and extrudes a mixture of powder and liquid introduced through the introduction pipe 55 to its one end portion, a casing 12 which is connected to one end portion of the extrusion pipe 60 and provided with a passage through which a fluid of the extruded mixture is made to flow, and a stirrer 15 which is disposed within the casing 12 and comprised of a shaft portion 14 connected to a drive source 20 and a stirring blade 16 attached to the external surface of the shaft portion 14. A funnel-shaped powder introducing device 57 is attached to the powder introduction port 24, a feeder 54 for conveying powder is disposed in the powder introducing device 57, and the feeder 54 is connected to an oscillatory rotation drive source 53.