Patents by Inventor Nobuaki Fujise

Nobuaki Fujise has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bone-pathobolism treating agent
    Patent number: 6919312
    Abstract: A novel bone-pathobolism treating agent is provided. A bone-pathobolism treating agent comprising at least one substance selected from the group consisting of osteoclastogenesis inhibitory factor (OCIF), its homologs, and its variants, and a polysaccharide or its derivatives. As the polysaccharide or its derivatives, heparin, dextran sulfate and the like can be used. A bone-pathobolism treating agent is provided which has excellent therapeutic effect on bone-pathobolism such as osteoporosis, hypercalcemia, or chronic articular rheumatism and persistance of the activity. The agent is useful as a medicine.
    Type: Grant
    Filed: April 12, 2001
    Date of Patent: July 19, 2005
    Assignee: Sankyo Co., Ltd.
    Inventors: Shinichi Mochizuki, Nobuaki Fujise, Chiharu Masuyama, Eisuke Tsuda, Kanji Higashio
  • Novel peptide and screening method by using the same
    Publication number: 20030092065
    Abstract: There is provided a novel peptide, a method of screening using the peptide, and an antibody obtained by the method of screening.
    Type: Application
    Filed: July 9, 2002
    Publication date: May 15, 2003
    Inventors: Naohiro Washida, Ken Takahashi, Toshiko Satake, Nobuaki Fujise, Hideki Tanaka, Masayoshi Kuriyama
  • Bone-pathobolism treating agent
    Publication number: 20010031725
    Abstract: A novel bone-pathobolism treating agent is provided.
    Type: Application
    Filed: April 12, 2001
    Publication date: October 18, 2001
    Inventors: Shinichi Mochizuki, Nobuaki Fujise, Chiharu Masuyama, Eisuke Tsuda, Kanji Higashio
  • Treatment of fibrosis by HGF
    Patent number: 6303126
    Abstract: The present invention relates to a method for treating fibrosis caused by excessive collagen deposition. The method involves administering Hepatocyte Growth Factors (HGFs). The HGFs accelerate the decomposition of the collagen when administered in an effective amount.
    Type: Grant
    Filed: May 6, 1998
    Date of Patent: October 16, 2001
    Assignees: Snow Brand Brand Milk Products Co., Ltd, Sumitomo Pharmaceuticals Co., Ltd.
    Inventors: Toshikazu Nakamura, Akira Shiota, Nobuaki Fujise, Mitsuo Namiki
  • Agent accelerating collagen decomposition
    Patent number: 5840311
    Abstract: The present invention relates to an agent accelerating collagen decomposition and a therapeutic agent for fibrosis disorder containing HGFs (Hepatocyte Growth Factors) as an active ingredient. The active ingredients HGFs accelerate the decomposition of collagen (increase of collagenase activity), and can effectively treat fibrosis disorder by the acceleration of collagen decomposition. Therefore, according to the present invention, the prevention and treatment of a disease due to reduced collagenase activity and fibrosis disorders characterized by excessive production of fibroblast-derived connective tissue matrix are possible.
    Type: Grant
    Filed: December 11, 1996
    Date of Patent: November 24, 1998
    Assignees: Toshikazu Nakamura, Snow Brand Milk Products Co., Ltd., Sumitomo Pharmaceuticals Co., Ltd.
    Inventors: Toshikazu Nakamura, Akira Shiota, Nobuaki Fujise, Mitsuo Namiki
  • Medicinal compositions for the improvement of blood coagulation comprising TCF-II
    Patent number: 5714461
    Abstract: Blood coagulation normalizing agents comprising effective ingredient of TCF-II.The blood coagulation normalizing agents of the present invention comprised of glycoprotein TCF-II produced by human fibroblast cells and accelerates the production of blood coagulation factor and increases platelet count to treat abnormal blood coagulation such as disseminated intravascular coagulation (DIC) and decreased platelet count caused by administration of cisplatin.
    Type: Grant
    Filed: January 19, 1995
    Date of Patent: February 3, 1998
    Assignee: Snow Brand Milk Products Co., Ltd.
    Inventors: Hiroaki Masunaga, Nobuaki Fujise
  • Treatment of endometriosis
    Patent number: 5166200
    Abstract: A remedy for endometriosis comprising, as an active ingredient, 14.alpha.-hydroxy-4-androstene-3,6,17-trione or an ester derivative thereof, can effectively treat endometriosis by the strong aromatase-inhibitory activity without giving serious side effects.
    Type: Grant
    Filed: April 11, 1991
    Date of Patent: November 24, 1992
    Assignee: Snow Brand Milk Products Company, Limited
    Inventors: Nobuaki Fujise, Yasushi Yamashita, Hiroaki Takaoka, Nobuyoshi Honda, Makoto Yoshihama