Patents by Inventor Nobuaki Kikyo

Nobuaki Kikyo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INDUCED PLURIPOTENT STEM CELLS
    Publication number: 20170267978
    Abstract: Described herein is a major breakthrough in nuclear reprogramming and induced pluripotent stem cell (iPSC) technology. Fusion of the powerful transcription activation domain (TAD) of MyoD to the Oct4 protein makes iPSCs generation faster, more efficient, purer, safer and feeder-free. Also, disclosed herein is the first report of the use of a TAD fused to a transcription factor as a method for making iPSCs. By combining transcription factors and TADs, this approach to nuclear reprogramming can have a range of applications from inducing pluriopotency to inducing transdifferentiation without transitioning through iPSCs.
    Type: Application
    Filed: January 11, 2017
    Publication date: September 21, 2017
    Inventors: Nobuaki Kikyo, Hiroyuki Hirai
  • Induced pluripotent stem cells
    Patent number: 9580689
    Abstract: Described herein is a major breakthrough in nuclear reprogramming and induced pluripotent stem cell (iPSC) technology. Fusion of the powerful transcription activation domain (TAD) of MyoD to the Oct4 protein makes iPSCs generation faster, more efficient, purer, safer and feeder-free. Also, disclosed herein is the first report of the use of a TAD fused to a transcription factor as a method for making iPSCs. By combining transcription factors and TADs, this approach to nuclear reprogramming can have a range of applications from inducing pluriopotency to inducing transdifferentiation without transitioning through iPSCs.
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: February 28, 2017
    Assignee: Regents of the University of Minnesota
    Inventors: Nobuaki Kikyo, Hiroyuki Hirai
  • METHOD OF EFFICIENTLY CONVERTING NON-CARDIAC CELLS INTO CARDIOVASCULAR CELLS
    Publication number: 20140377236
    Abstract: Described herein is a method for generating cardiomyocytes (CMs) from non-cardiac cells.
    Type: Application
    Filed: June 20, 2014
    Publication date: December 25, 2014
    Inventors: Hiroyuki Hirai, Nobuaki Kikyo
  • INDUCED PLURIPOTENT STEM CELLS
    Publication number: 20130195812
    Abstract: Described herein is a major breakthrough in nuclear reprogramming and induced pluripotent stem cell (iPSC) technology. Fusion of the powerful transcription activation domain (TAD) of MyoD to the Oct4 protein makes iPSCs generation faster, more efficient, purer, safer and feeder-free. Also, disclosed herein is the first report of the use of a TAD fused to a transcription factor as a method for making iPSCs. By combining transcription factors and TADs, this approach to nuclear reprogramming can have a range of applications from inducing pluriopotency to inducing transdifferentiation without transitioning through iPSCs.
    Type: Application
    Filed: July 22, 2011
    Publication date: August 1, 2013
    Applicant: Regents of the University of Minnesota
    Inventors: Nobuaki Kikyo, Hiroyuki Hirai