Patents by Inventor Nobuhiro Morishima

Nobuhiro Morishima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody against cleavage product of vimentin
    Patent number: 7029864
    Abstract: The present invention provides the antibody that react with the cleavage product of vimentin, but not with intact vimentin.
    Type: Grant
    Filed: May 21, 2002
    Date of Patent: April 18, 2006
    Assignee: Riken
    Inventors: Nobuhiro Morishima, Keiko Nakanishi, Takehiko Shibata
  • Programmed cell death and caspase-12
    Patent number: 6642368
    Abstract: This invention relates to nucleic acids encoding caspase-12, proteins encoded by casp-12 nucleic acids, vectors, and hosts transformed with vectors. Caspase-12 is a member of the caspase family, which also includes mammalian interleukin-1&bgr;-converting enzyme (ICE). Caspases are thought to carry out the execution phase of apoptosis in a cascade of proteolytic events. The invention also relates to the use of caspase-12 to induce programmed cell death.
    Type: Grant
    Filed: April 14, 1999
    Date of Patent: November 4, 2003
    Assignee: The General Hospital Corporation
    Inventors: Junying Yuan, Nobuhiro Morishima
  • Endonuclease
    Patent number: 6528296
    Abstract: The present invention relates to a site-specific endonuclease which recognizes a specific nucleotide sequence, to a gene coding for the endonuclease, to a recombinant vector containing the gene, to a transformant containing the vector, and to a process for producing the endonuclease.
    Type: Grant
    Filed: August 20, 2001
    Date of Patent: March 4, 2003
    Assignee: Institute of Physical and Chemical Research
    Inventors: Nobuhiro Morishima, Hikaru Mizumura, Takehiko Shibata
  • Cell death inhibitory protein
    Publication number: 20020164738
    Abstract: The present invention provides a protein which inhibits the activation of caspase-12 and uses of the protein.
    Type: Application
    Filed: February 16, 2001
    Publication date: November 7, 2002
    Inventors: Nobuhiro Morishima, Takehiko Shibata
  • Antibody against cleavage product of vimentin
    Publication number: 20020137110
    Abstract: The present invention provides the antibody that react with the cleavage product of vimentin, but not with intact vimentin.
    Type: Application
    Filed: May 21, 2002
    Publication date: September 26, 2002
    Inventors: Nobuhiro Morishima, Keiko Nakanishi, Takehiko Shibata
  • Antibody against cleavage product or vimentin
    Patent number: 6417336
    Abstract: The present invention provides the antibody that react with the cleavage product of vimentin, but not with intact vimentin.
    Type: Grant
    Filed: July 5, 2000
    Date of Patent: July 9, 2002
    Assignee: Riken
    Inventors: Nobuhiro Morishima, Keiko Nakanishi, Takehiko Shibata
  • Endonuclease
    Patent number: 6280942
    Abstract: The present invention relates to a site-specific endonuclease which recognizes a specific nucleotide sequence, to a gene coding for the endonuclease, to a recombinant vector containing the gene, to a transformant containing the vector, and to a process for producing the endonuclease.
    Type: Grant
    Filed: May 20, 1999
    Date of Patent: August 28, 2001
    Assignee: Institute of Physical and Chemical Research
    Inventors: Nobuhiro Morishima, Hikaru Mizumura, Takehiko Shibata