Patents by Inventor Nobuhiro Oikawa

Nobuhiro Oikawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230142119
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Application
    Filed: July 8, 2022
    Publication date: May 11, 2023
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazutomo KINOSHITA, Kohsuke ASOH, Noriyuki FURUICHI, Toshiya ITO, Hatsuo KAWADA, Nobuya ISHII, Hiroshi SAKAMOTO, WooSang HONG, MinJeong PARK, Yoshiyuki ONO, Yasuharu KATO, Kenji MORIKAMI, Takashi EMURA, Nobuhiro OIKAWA
  • Publication number: 20220306578
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Application
    Filed: April 29, 2020
    Publication date: September 29, 2022
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazutomo KINOSHITA, Kohsuke ASOH, Noriyuki FURUICHI, Toshiya ITO, Hatsuo KAWADA, Nobuya ISHII, Hiroshi SAKAMOTO, WooSang HONG, MinJeong PARK, Yoshiyuki ONO, Yasuharu KATO, Kenji MORIKAMI, Takashi EMURA, Nobuhiro OIKAWA
  • Publication number: 20200017442
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Application
    Filed: January 4, 2019
    Publication date: January 16, 2020
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazutomo KINOSHITA, Kohsuke ASOH, Noriyuki FURUICHI, Toshiya ITO, Hatsuo KAWADA, Nabuya ISHII, Hiroshi SAKAMOTO, WooSang HONG, MinJeong PARK, Yoshiyuki ONO, Yasuharu KATO, Kenji MORIKAMI, Takashi EMURA, Nobuhiro OIKAWA
  • Publication number: 20160340308
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Application
    Filed: July 28, 2016
    Publication date: November 24, 2016
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazutomo Kinoshita, Kohsuke ASOH, Noriyuki FURUICHI, Toshiya ITO, Hatsuo KAWADA, Nobuya ISHll, Hiroshi SAKAMOTO, WooSang HONG, MinJeong PARK, Yoshiyuki ONO, Yasuharu KATO, Kenji MORIKAMI, Takashi EMURA, Nobuhiro OIKAWA
  • Patent number: 9440922
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: September 13, 2016
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazutomo Kinoshita, Kohsuke Asoh, Noriyuki Furuichi, Toshiya Ito, Hatsuo Kawada, Nobuya Ishii, Hiroshi Sakamoto, WooSang Hong, MinJeong Park, Yoshiyuki Ono, Yasuharu Kato, Kenji Morikami, Takashi Emura, Nobuhiro Oikawa
  • Patent number: 9126931
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Grant
    Filed: June 9, 2010
    Date of Patent: September 8, 2015
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazutomo Kinoshita, Kohsuke Asoh, Noriyuki Furuichi, Toshiya Ito, Hatsuo Kawada, Nobuya Ishii, Hiroshi Sakamoto, WooSang Hong, MinJeong Park, Yoshiyuki Ono, Yasuharu Kato, Kenji Morikami, Takashi Emura, Nobuhiro Oikawa
  • Publication number: 20150150845
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Application
    Filed: February 11, 2015
    Publication date: June 4, 2015
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazutomo KINOSHITA, Kohsuke ASOH, Noriyuki FURUICHI, Toshiya ITO, Hatsuo KAWADA, Nobuya ISHII, Hiroshi SAKAMOTO, WooSang HONG, MinJeong PARK, Yoshiyuki ONO, Yasuharu KATO, Kenji MORIKAMI, Takashi EMURA, Nobuhiro OIKAWA
  • Patent number: 8609656
    Abstract: The present invention provides a compound represented by the formula (1): wherein R1, R2 and R5 are each independently selected from a hydrogen atom, a halogen atom, a C1-C6 alkyl is substituted with a halogen atom and the like; R3 and R4 are each independently selected from a hydrogen atom, a halogen atom, a substituted C1-C6 alkyl group and the like; R6 and R7 are each independently selected from a hydrogen atom and a halogen atom; Z1 and Z2 are each independently selected from a hydrogen atom, a hydroxyl group and —O(CHR11)OC(?O)R12; Q is a group of the formula: (wherein G1 is C—Y2 or N; a ring A is a benzene ring or a 5- to 6-membered unsaturated heterocycle) a pharmaceutically acceptable salt thereof or a prodrug thereof.
    Type: Grant
    Filed: February 23, 2005
    Date of Patent: December 17, 2013
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Nobuhiro Oikawa, Eisaku Mizuguchi, Kenji Morikami, Nobuo Shimma, Nobuya Ishii, Toshiyuki Tsukaguchi, Sawako Ozawa
  • Patent number: 8299252
    Abstract: It is intended to provide a compound represented by the formula (1): [wherein Ar is an arylene group to be attached selected from the following formula (2): (wherein * represents a binding site to a nitrogen atom and ** represents a binding site to T); T represents —(O)n—R; R represents a C1-C6 alkyl group or the like; n represents 0 or 1; X represents O or the like; R2, R3 and R4 are independently selected from a hydrogen atom or C1-C3 alkyl; or R2 and R3 may join together with an urea structure containing the nitrogen atoms to which they bind to form a 5- or 6-membered heterocycle; Y represents CH or N], or a pharmaceutically acceptable salt thereof or a prodrug thereof and a pharmaceutical composition containing the same.
    Type: Grant
    Filed: August 4, 2006
    Date of Patent: October 30, 2012
    Assignees: Chugai Seiyaku Kabushiki Kaisha, The University of Tokyo
    Inventors: Sawako Ozawa, Nobuhiro Oikawa, Eisaku Mizuguchi, Hirosato Ebiike, Fumio Watanabe, Kenji Morikami, Nobuo Shimma, Nobuya Ishii, Toshiyuki Tsukaguchi
  • Publication number: 20120083488
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Application
    Filed: June 9, 2010
    Publication date: April 5, 2012
    Inventors: Kazutomo Kinoshita, Kohsuke Asoh, Noriyuki Furuichi, Toshiya Ito, Hatsuo Kawada, Nobuya Ishii, Hiroshi Sakamoto, WooSang Hong, MinJeong Park, Yoshiyuki Ono, Yashuharu Kato, Kenji Morikami, Takashi Emura, Nobuhiro Oikawa
  • Publication number: 20100168430
    Abstract: It is intended to provide a compound represented by the formula (1): [wherein Ar is an arylene group to be attached selected from the following formula (2): (wherein * represents a binding site to a nitrogen atom and ** represents a binding site to T); T represents —(O)n—R; R represents a C1-C6 alkyl group or the like; n represents 0 or 1; X represents O or the like; R2, R3 and R4 are independently selected from a hydrogen atom or C1-C3 alkyl; or R2 and R3 may join together with an urea structure containing the nitrogen atoms to which they bind to form a 5- or 6-membered heterocycle; Y represents CH or N], or a pharmaceutically acceptable salt thereof or a prodrug thereof and a pharmaceutical composition containing the same.
    Type: Application
    Filed: August 4, 2006
    Publication date: July 1, 2010
    Applicants: Chugai Seiyaku Kabushiki Kaisha, The University of Tokyo
    Inventors: Sawako Ozawa, Nobuhiro Oikawa, Eisaku Mizuguchi, Hirosato Ebiike, Fumio Watanabe, Kenji Morikami, Nobuo Shimma, Nobuya Ishii, Toshiyuki Tsukaguchi, Yasuhiro Tamaki, Hidenori Takahashi
  • Patent number: 7459561
    Abstract: N-substituted carbamoyloxyalkyl-azolium derivatives which have antifungal activity and are useful for the treatment of fungal diseases.
    Type: Grant
    Filed: August 15, 2006
    Date of Patent: December 2, 2008
    Assignee: Basilea Pharmaceutica AG
    Inventors: Hiroshi Fukuda, Tadakatsu Hayase, Eisaku Mizuguchi, Nobuo Shimma, Jun Ohwada, Nobuhiro Oikawa, Masahiro Sakaitani, Masao Tsukazaki, Isao Umeda
  • Publication number: 20080119466
    Abstract: The present invention provides a compound represented by the formula (1): wherein R1, R2 and R5 are each independently selected from a hydrogen atom, a halogen atom, a C1-C6 alkyl is substituted with a halogen atom and the like; R3 and R4 are each independently selected from a hydrogen atom, a halogen atom, a substituted C1-C6 alkyl group and the like; R6 and R7 are each independently selected from a hydrogen atom and a halogen atom; Z1 and Z2 are each independently selected from a hydrogen atom, a hydroxyl group and —O(CHR11)OC(?O)R12; Q is a group of the formula: (wherein G1 is C—Y2 or N; a ring A is a benzene ring or a 5- to 6-membered unsaturated heterocycle) a pharmaceutically acceptable salt thereof or a prodrug thereof.
    Type: Application
    Filed: February 23, 2005
    Publication date: May 22, 2008
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Nobuhiro Oikawa, Eisaku Mizuguchi, Kenji Morikami, Nobuo Shimma, Nobuya Ishii, Toshiyuki Tsukaguchi, Sawako Ozawa
  • Patent number: 7189858
    Abstract: N-substituted carbamoyloxyalkyl-azolium derivatives Which have antifungal activity and are useful for the treatment of fungal diseases.
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: March 13, 2007
    Assignee: Basilea Pharmaceutica AG
    Inventors: Hiroshi Fukuda, Tadakatsu Hayase, Eisaku Mizuguchi, Nobuo Shimma, Jun Ohwada, Nobuhiro Oikawa, Masahiro Sakaitani, Masao Tsukazaki, Isao Umeda
  • Publication number: 20070027322
    Abstract: N-substituted carbamoyloxyalkyl-azolium derivatives which have antifungal activity and are useful for the treatment of fungal diseases.
    Type: Application
    Filed: August 15, 2006
    Publication date: February 1, 2007
    Inventors: Hiroshi Fukuda, Tadakatsu Hayase, Eisaku Mizuguchi, Nobuo Shimma, Jun Ohwada, Nobuhiro Oikawa, Masahiro Sakaitani, Masao Tsukazaki, Isao Umeda
  • Patent number: 7151182
    Abstract: N-substituted carbamoyloxyalkyl-azolium derivatives which have antifungal activity and are useful for the treatment of fungal diseases.
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: December 19, 2006
    Assignee: Basilea Pharmaceutica AG
    Inventors: Hiroshi Fukuda, Tadakatsu Hayase, Eisaku Mizuguchi, Nobuo Shimma, Jun Ohwada, Nobuhiro Oikawa, Masahiro Sakaitani, Masao Tsukazaki, Isao Umeda
  • Patent number: 6976731
    Abstract: In a vehicle body structure, an accommodation concavity is provided in a floor panel. A pair of side members each having a nearly vertical first side surface portion extend bilaterally of the accommodation concavity. The floor panel is composed of a first floor panel having a first bottom surface portion serving as the bottom surface of the accommodation concavity, and second side surface portions erected in a nearly vertical direction from the first bottom surface portion and placed adjacent to the first side surface portions; and second floor panels each having a second bottom surface portion placed above the side member, and a third side surface portion erected in a nearly vertical direction from the second bottom surface portion and placed adjacent to and outwardly of the first side surface portion in a vehicle width direction.
    Type: Grant
    Filed: January 14, 2004
    Date of Patent: December 20, 2005
    Assignees: Mitsubishi Jidosha Kogyo Kabushiki Kaisha, Metaltech Ltd.
    Inventors: Keisuke Shibata, Nobuhiro Oikawa, Yoshiyuki Koshita, Toshimitsu Yagi
  • Patent number: 6938950
    Abstract: A vehicle body structure in which a ridge of a front side member is continuous with a ridge of a dash brace to make it possible to efficiently transmit an impact force, and which is capable of realizing an intended deformation of the front side member suited to the impact force, while effectively utilizing a reaction force generated in a side frame member. A front portion of the dash brace is inserted into the front side member through a notch formed in a dash panel, and is overlapped with and spot-welded to a side face of the front side member, whereby the ridge of the front side member is directly continuous with the ridge of the dash brace.
    Type: Grant
    Filed: April 9, 2004
    Date of Patent: September 6, 2005
    Assignees: Mitsubishi Jidosha Kogyo Kabushiki Kaisha, Mitsubishi Jidosha Engineering Kabushiki Kaisha
    Inventors: Yoshito Nagafuchi, Nobuhiro Oikawa, Katsuhiko Takashina
  • Publication number: 20050038038
    Abstract: N-substituted carbamoyloxyalkyl-azolium derivatives Which have antifungal activity and are useful for the treatment of fungal diseases.
    Type: Application
    Filed: September 3, 2004
    Publication date: February 17, 2005
    Inventors: Hiroshi Fukuda, Tadakatsu Hayase, Eisaku Mizuguchi, Nobuo Shimma, Jun Ohwada, Nobuhiro Oikawa, Masahiro Sakaitani, Masao Tsukazaki, Isao Umeda
  • Publication number: 20050038075
    Abstract: N-substituted carbamoyloxyalkyl-azolium derivatives which have antifungal activity and are useful for the treatment of fungal diseases.
    Type: Application
    Filed: September 3, 2004
    Publication date: February 17, 2005
    Inventors: Hiroshi Fukuda, Tadakatsu Hayase, Eisaku Mizuguchi, Nobuo Shimma, Jun Ohwada, Nobuhiro Oikawa, Masahiro Sakaitani, Masao Tsukazaki, Isao Umeda