Patents by Inventor Nobuhisa Fujita

Nobuhisa Fujita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic intermediate of oxazole compound and method for producing the same
    Patent number: 8598358
    Abstract: An object of the present invention is to provide a method for producing an oxazole compound in a high yield.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: December 3, 2013
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Akihiro Yamamoto, Koichi Shinhama, Nobuhisa Fujita, Shinji Aki, Shin Ogasawara, Naoto Utsumi
  • Epoxy compound and method for manufacturing the same
    Patent number: 8552188
    Abstract: The present invention provides a novel intermediate for manufacturing a 2,3-dihydroimidazo[2,1-b]oxazole compound with a high yield and a high purity, and a manufacturing method of the intermediate. The present invention provides an epoxy compound represented by the general formula (2): wherein, R1 represents a hydrogen or a lower alkyl group; and R2 represents a piperidyl group represented by the general formula (A1): (wherein, R3 represents a phenoxy group having a halogen-substituted lower alkoxy group substituted on a phenyl group, and the like) and the like; and n represents an integer of 1 to 6, a manufacturing method of the epoxy compound, and a manufacturing method of an oxazole compound using the epoxy method.
    Type: Grant
    Filed: November 15, 2012
    Date of Patent: October 8, 2013
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Hidetsugu Tsubouchi, Yoshikazu Haraguchi, Satoshi Hayakawa, Naoto Utsumi, Shinichi Taira, Yoshihisa Tanada, Nobuhisa Fujita, Koichi Shinhama, Kimiyoshi Annaka, Takuya Furuta
  • Epoxy compound and method for manufacturing the same
    Patent number: 8344148
    Abstract: The present invention provides a novel intermediate for manufacturing a 2,3-dihydroimidazo[2,1-b]oxazole compound with a high yield and a high purity, and a manufacturing method of the intermediate. The present invention provides an epoxy compound represented by the general formula (2): wherein, R1 represents hydrogen or a lower alkyl group; and R2 represents a piperidyl group represented by the general formula (A1): (wherein, R3 represents a phenoxy group having a halogen-substituted lower alkoxy group substituted on a phenyl group, and the like) and the like; and n represents an integer of 1 to 6, a manufacturing method of the epoxy compound, and a manufacturing method of an oxazole compound using the epoxy compound.
    Type: Grant
    Filed: May 7, 2008
    Date of Patent: January 1, 2013
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Hidetsugu Tsubouchi, Yoshikazu Haraguchi, Satoshi Hayakawa, Naoto Utsumi, Shinichi Taira, Yoshihisa Tanada, Nobuhisa Fujita, Koichi Shinhama, Kimiyoshi Annaka, Takuya Furuta
  • SYNTHETIC INTERMEDIATE OF OXAZOLE COMPOUND AND METHOD FOR PRODUCING THE SAME
    Publication number: 20120302757
    Abstract: An object of the present invention is to provide a method for producing an oxazole compound in a high yield.
    Type: Application
    Filed: January 28, 2011
    Publication date: November 29, 2012
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Akihiro Yamamoto, Koichi Shinhama, Nobuhisa Fujita, Shinji Aki, Shin Ogasawara, Naoto Utsumi
  • Process for producing 1-(3,4-dichlorobenzyl)-5-octylbiguanide or a salt thereof
    Patent number: 7868207
    Abstract: The present invention provides a process for producing 1-(3,4-dichlorobenzyl)-5-octylbiguanide or a salt thereof, the process comprising reacting 1-cyano-3-octylguanidine or a salt thereof, with 3,4-dichlorobenzylamine or a salt thereof, in an ester-based organic solvent. According to the present invention, the reaction can be carried out at a low temperature using general-purpose equipment, and 1-(3,4-dichlorobenzyl)-5-octylbiguanide or a salt thereof can be produced in a high yield by a safe and easy process.
    Type: Grant
    Filed: August 28, 2007
    Date of Patent: January 11, 2011
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Yoshihiko Okaichi, Nobuhito Tada, Daisuke Nomi, Nobuhisa Fujita, Koichi Tsuji, Taizo Yamaguchi, Yasuaki Muguruma, Hisayuki Tsujimori
  • EPOXY COMPOUND AND METHOD FOR MANUFACTURING THE SAME
    Publication number: 20100217005
    Abstract: The present invention provides a novel intermediate for manufacturing a 2,3-dihydroimidazo[2,1-b]oxazole compound with a high yield and a high purity, and a manufacturing method of the intermediate. The present invention provides an epoxy compound represented by the general formula (2): wherein, R1 represents hydrogen or a lower alkyl group; and R2 represents a piperidyl group represented by the general formula (A1): (wherein, R3 represents a phenoxy group having a halogen-substituted lower alkoxy group substituted on a phenyl group, and the like) and the like; and n represents an integer of 1 to 6, a manufacturing method of the epoxy compound, and a manufacturing method of an oxazole compound using the epoxy compound.
    Type: Application
    Filed: May 7, 2008
    Publication date: August 26, 2010
    Inventors: Hidetsugu Tsubouchi, Yoshikazu Haraguchi, Satoshi Hayakawa, Naoto Utsumi, Shinichi Taira, Yoshihisa Tanada, Nobuhisa Fujita, Koichi Shinhama, Kimiyoshi Annaka, Takuya Furuta
  • PROCESS FOR PRODUCING 1-(3,4-DICHLOROBENZYL)-5-OCTYLBIGUANIDE OR A SALT THEREOF
    Publication number: 20090270653
    Abstract: The present invention provides a process for producing 1-(3,4-dichlorobenzyl)-5-octylbiguanide or a salt thereof, the process comprising reacting 1-cyano-3-octylguanidine or a salt thereof, with 3,4-dichlorobenzylamine or a salt thereof, in an ester-based organic solvent. According to the present invention, the reaction can be carried out at a low temperature using general-purpose equipment, and 1-(3,4-dichlorobenzyl)-5-octylbiguanide or a salt thereof can be produced in a high yield by a safe and easy process.
    Type: Application
    Filed: August 28, 2007
    Publication date: October 29, 2009
    Inventors: Yoshihiko Okaichi, Nobuhito Tada, Daisuke Nomi, Nobuhisa Fujita, Koichi Tsuji, Taizo Yamaguchi, Yasuaki Muguruma, Hisayuki Tsujimori