Patents by Inventor Nobuko Fukushima

Nobuko Fukushima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-imidazoline derivatives
    Patent number: 5116858
    Abstract: 4-Imidazoline derivatives represented by the formula (I) and/or formula (II): ##STR1## wherein R.sup.1 represents C.sub.1 -C.sub.8 alkyl, C.sub.3 -C.sub.8 alkenyl, C.sub.3 -C.sub.8 alkynyl, C.sub.3 -C.sub.8 cycloalkyl, or optionally substituted aralkyl; R.sup.2 and R.sup.3 independently represent hydrogen, C.sub.3 -C.sub.20 alkyl, C.sub.3 -C.sub.20 alkenyl, C.sub.3 -C.sub.20 alkynyl, C.sub.3 -C.sub.20 alkoxy, C.sub.3 -C.sub.20 alkenyloxy, C.sub.3 -C.sub.20 alkynyloxy, C.sub.3 -C.sub.8 cyloalkyl, C.sub.1 -C.sub.10 alkylthio, or optionally substituted aralkyl or aralkyloxy; R.sup.4 represents C.sub.1 -C.sub.6 alkyl, C.sub.3 -C.sub.8 cycloalkyl, or optionally substituted aralkyl; provided that R.sup.2 and R.sup.3 cannot be hydrogen at the same time, and pharmaceutically acceptable salts thereof. A pharmaceutical formulation containing the compound is also provided.
    Type: Grant
    Filed: April 26, 1990
    Date of Patent: May 26, 1992
    Assignee: Mitsubishi Kasei Corporation
    Inventors: Yoshio Hayashi, Yasuhiro Morinaka, Masaki Shinoda, Hiroyoshi Nishi, Kazutoshi Watanabe, Nobuko Fukushima
  • Lipid-peroxide formation inhibiting composition and novel compounds useful therefor
    Patent number: 5089515
    Abstract: A lipid-peroxide formation inhibitor useful as a preventive medicine and/or therapeutic medicine against various ischemic diseases and accompanying diseases such as various brain diseases, heart diseases and peripheral circulatory diseases and novel pyrazolone derivatives having such inhibitory activity and their pharmaceutically acceptable salts.
    Type: Grant
    Filed: October 31, 1990
    Date of Patent: February 18, 1992
    Assignee: Mitsubishi Kasei Corporation
    Inventors: Yasuhiro Morinaka, Hiroyoshi Nishi, Toshiaki Watanabe, Satoshi Yuki, Hiroko Sakurai, Yoshio Hayashi, Nobuko Fukushima
  • Pyrazoline derivatives
    Patent number: 4990619
    Abstract: A lipid-peroxide formation inhibitor useful as a preventive medicine and/or therapeutic medicine against various ischemic diseases and accompanying diseases such as various brain diseases, heart diseases and peripheral circulatory diseases and novel pyrazolone derivatives having such inhibitory activity and their pharmaceutically acceptable salts.
    Type: Grant
    Filed: December 18, 1989
    Date of Patent: February 5, 1991
    Assignee: Mitsubishi Kasei Corporation
    Inventors: Yasuhiro Morinaka, Hiroyoshi Nishi, Toshiaki Watanabe, Satoshi Yuki, Hiroko Sakurai, Yoshio Hayashi, Nobuko Fukushima
  • Lipid-peroxide formation inhibiting composition and novel compounds useful therefor
    Patent number: 4906644
    Abstract: A lipid-peroxide formation inhibitor useful as a preventive medicine and/or therapeutic medicine against various ischemic diseases and accompanying diseases such as various brain diseases, heart diseases and peripheral circulatory diseases and novel pyrazolone derivatives having such inhibitory activity and their pharmaceutically acceptable salts.
    Type: Grant
    Filed: November 20, 1987
    Date of Patent: March 6, 1990
    Assignee: Mitsubishi Kasei Corporation
    Inventors: Yasuhiro Morinaka, Hiroyoshi Nishi, Toshiaki Watanabe, Satoshi Yuki, Hiroko Sakurai, Yoshio Hayashi, Nobuko Fukushima