Patents by Inventor Nobuko KOSHIKAWA

Nobuko KOSHIKAWA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AGENT TARGETING DOUBLE-MEMBRANE ORGANELLE DNA
    Publication number: 20220193241
    Abstract: The present invention provides a drug for a pathological condition including mitochondria-related disease by a conjugate of a double-membrane organelle DNA sequence recognizing compound and a double-membrane organelle localizable compound. The present invention provides a conjugate in which a double-membrane organelle localizable lipophilic cation is attached to linear PI polyamide that specifically binds to a double-membrane organelle DNA sequence, a linear PI polyamide-TPP conjugate targeting the mitochondrial DNA mutation or polymorphism, comprising the conjugate, and a pharmaceutical composition comprising the conjugate.
    Type: Application
    Filed: March 19, 2020
    Publication date: June 23, 2022
    Applicant: CHIBA-PREFECTURE
    Inventors: Hiroki NAGASE, Takayoshi WATANABE, Nobuko KOSHIKAWA, Nanami YASUI