Patents by Inventor Nobumichi Hozumi

Nobumichi Hozumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Animal model of the human immune system
    Patent number: 5663481
    Abstract: The present invention relates to a non-human chimeric mammal having characteristics of a functional human immune system and having functional human lymphocytes reconstituted in the mammal's lymphopoietic tissue, particularly the spleen. The invention also relates to a method of preparing a non-human chimeric mammal, having characteristics of a functional human immune system, by engraftment of human peripheral blood leukocytes into an immunocompromised mammal. Use of the chimeric mammal as a model of the human immune system is described.
    Type: Grant
    Filed: August 6, 1993
    Date of Patent: September 2, 1997
    Assignee: Mount Sinai Hospital Corporation
    Inventors: Steven Gallinger, Nobumichi Hozumi, John C. Roder, Jasbir S. Sandhu, Baruch Shpitz